Search Results - "Tutol, Jasmine N"

Discovery and Characterization of a Naturally Occurring, Turn-On Yellow Fluorescent Protein Sensor for Chloride by Tutol, Jasmine N, Peng, Weicheng, Dodani, Sheel C

“…Fluorescent proteins have been extensively engineered and applied as optical indicators for chloride in a variety of biological contexts. Surprisingly, given…”
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Identification of mNeonGreen as a pH‐Dependent, Turn‐On Fluorescent Protein Sensor for Chloride by Tutol, Jasmine N., Kam, Hiu C., Dodani, Sheel C.

“…Chloride‐sensitive fluorescent proteins generated from laboratory evolution have a characteristic tyrosine residue that interacts with a chloride ion and…”
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Unlocking chloride sensing in the red at physiological pH with a fluorescent rhodopsin-based host by Phelps, Shelby M, Tutol, Jasmine N, Advani, Deeya, Peng, Weicheng, Dodani, Sheel C

“…Chloride is a vital ion for all forms of life. Protein-based fluorescent biosensors can enable researchers to visualize chloride in cells but remain…”
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Engineering the ChlorON Series: Turn-On Fluorescent Protein Sensors for Imaging Labile Chloride in Living Cells by Tutol, Jasmine N., Ong, Whitney S. Y., Phelps, Shelby M., Peng, Weicheng, Goenawan, Helen, Dodani, Sheel C.

“…Beyond its role as the “queen of electrolytes”, chloride can also serve as an allosteric regulator or even a signaling ion. To illuminate this essential anion…”
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Excitation ratiometric chloride sensing in a standalone yellow fluorescent protein is powered by the interplay between proton transfer and conformational reorganization by Chen, Cheng, Tutol, Jasmine N, Tang, Longteng, Zhu, Liangdong, Ong, Whitney S. Y, Dodani, Sheel C, Fang, Chong

“…Natural and laboratory-guided evolution has created a rich diversity of fluorescent protein (FP)-based sensors for chloride (Cl − ). To date, such sensors have…”
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A single point mutation converts a proton-pumping rhodopsin into a red-shifted, turn-on fluorescent sensor for chloride by Tutol, Jasmine N, Lee, Jessica, Chi, Hsichuan, Faizuddin, Farah N, Abeyrathna, Sameera S, Zhou, Qin, Morcos, Faruck, Meloni, Gabriele, Dodani, Sheel C

“…The visualization of chloride in living cells with fluorescent sensors is linked to our ability to design hosts that can overcome the energetic penalty of…”
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Discovery of a monomeric green fluorescent protein sensor for chloride by structure-guided bioinformatics by Peng, Weicheng, Maydew, Caden C, Kam, Hiu, Lynd, Jacob K, Tutol, Jasmine N, Phelps, Shelby M, Abeyrathna, Sameera, Meloni, Gabriele, Dodani, Sheel C

“…Chloride is an essential anion for all forms of life. Beyond electrolyte balance, an increasing body of evidence points to new roles for chloride in normal…”
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Coupling a Live Cell Directed Evolution Assay with Coevolutionary Landscapes to Engineer an Improved Fluorescent Rhodopsin Chloride Sensor by Chi, Hsichuan, Zhou, Qin, Tutol, Jasmine N, Phelps, Shelby M, Lee, Jessica, Kapadia, Paarth, Morcos, Faruck, Dodani, Sheel C

“…Our understanding of chloride in biology has been accelerated through the application of fluorescent protein-based sensors in living cells. These sensors can…”
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A recombinant platform to characterize the role of transmembrane protein hTMEM205 in Pt()-drug resistance and extrusion by Gallenito, Marc J, Qasim, Tahir S, Tutol, Jasmine N, Prakash, Ved, Dodani, Sheel C, Meloni, Gabriele

“…Platinum-coordination complexes are among the most effective chemotherapeutic drugs used in clinics for the treatment of cancer. Despite their efficacy, cancer…”
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An activity-based fluorescent sensor for the detection of the phenol sulfotransferase SULT1A1 in living cells by Baglia, Regina A, Mills, Kira R, Mitra, Koushambi, Tutol, Jasmine N, Ball, Darby, Page, Kierstin M, Kallu, Jyothi, Gottipolu, Sriharika, D'Arcy, Sheena, Nielsen, Steven O, Dodani, Sheel C

“…Human phenol sulfotransferases mediate the transfer of a sulfuryl moiety from the activated sulfate donor PAPS to hydroxy-containing substrates, altering…”
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Front Cover: Identification of mNeonGreen as a pH‐Dependent, Turn‐On Fluorescent Protein Sensor for Chloride (ChemBioChem 14/2019) by Tutol, Jasmine N., Kam, Hiu C., Dodani, Sheel C.

“…mNeonGreen: A bright idea for chloride: Chloride‐sensitive fluorescent proteins generated from natural and laboratory‐guided evolution have a characteristic…”
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