Search Results - "Tuszynski, J"

On the significance of the electrostatic differences between cancer and normal cells: Comment on: “Improving cancer treatments via dynamical biophysical models” by Kuznetsov et al by Tuszynski, J.A.

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An In Silico Investigation of the Molecular Interactions between Volatile Anesthetics and Actin by Truglia, Barbara, Carbone, Nicola, Ghadre, Ibrahim, Vallero, Sara, Zito, Marinella, Zizzi, Eric Adriano, Deriu, Marco Agostino, Tuszynski, J A

“…Volatile anesthetics (VAs) are medicinal chemistry compounds commonly used to enable surgical procedures for patients who undergo painful treatments and can be…”
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Charge-based interactions of antimicrobial peptides and general drugs with lipid bilayers by Ashrafuzzaman, Md, Tseng, C.-Y., Tuszynski, J.A.

“…Membrane-active agents (MAAs), such as antimicrobial peptides (AMPs) and chemotherapy drugs (CDs), induce ion pores/channels inside lipid bilayer membrane, as…”
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A search for the physical basis of the genetic code by Moghadam, S. Arbabi, Klobukowski, M., Tuszynski, J.A.

“…DNA contains the genetic code, which provides complete information about the synthesis of proteins in every living cell. Each gene encodes for a corresponding…”
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Ion pore formation in lipid bilayers and related energetic considerations by Ashrafuzzaman, Md, Tuszynski, J

“…Interactions between membrane proteins (MPs)/antimicrobial peptides (AMPs) and lipids play important roles in the creation and function of membrane transport…”
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Testing amino acid-codon affinity hypothesis using molecular docking by Moghadam, S. Arbabi, Preto, J., Klobukowski, M., Tuszynski, J.A.

“…Genetic code refers to a set of rules that assign trinucleotides called codons to amino acids in the process of protein synthesis. Investigating the genetic…”
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Anisotropic elastic properties of microtubules by TUSZYNSKI, J. A, LUCHKO, T, PORTET, S, DIXON, J. M

“…We review and model the experimental parameters which characterize elastic properties of microtubules. Three macroscopic estimates are made of the anisotropic…”
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Cell death and survival due to cytotoxic exposure modelled as a two-state Ising system by Arbabi Moghadam, S, Rezania, V, Tuszynski, J A

“…Cancer chemotherapy agents are assessed for their therapeutic utility primarily by their ability to cause apoptosis of cancer cells and their potency is given…”
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Quantum metabolism explains the allometric scaling of metabolic rates by Demetrius, Lloyd, Tuszynski, J. A.

“…-dimensional space (…”
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Estimation of the number of biophotons involved in the visual perception of a single-object image: Biophoton intensity can be considerably higher inside cells than outside by Bókkon, I., Salari, V., Tuszynski, J.A., Antal, I.

“…Recently, we have proposed a redox molecular hypothesis about the natural biophysical substrate of visual perception and imagery [1,6]. Namely, the retina…”
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Nonlinear ionic pulses along microtubules by Sekulić, D. L., Satarić, B. M., Tuszynski, J. A., Satarić, M. V.

“…Microtubules are cylindrically shaped cytoskeletal biopolymers that are essential for cell motility, cell division and intracellular trafficking. Here, we…”
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Theorizing how the brain encodes consciousness based on negentropic entanglement by Poznanski, R R, Cacha, L A, Latif, A Z A, Salleh, S H, Ali, J, Yupapin, P, Tuszynski, J A, Tengku, M A

“…The physicality of subjectivity is explained through a theoretical conceptualization of guidance waves informing meaning in negentropically entangled…”
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Metabolic targeting and antagonism of the EGFRvIII/PDK1 axis in temozolomide resistant glioblastoma models by Velpula, K.K, Guda, M.R, Sahu, K, Tuszynski, J, Asuthkar, S, Martin, S.E, Lathia, J.D, Tsung, A.J

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Thermal hysteresis in microtubule assembly/disassembly dynamics: The aging-induced degradation of tubulin dimers by Wu, R., Guzman-Sepulveda, J.R., Kalra, A.P., Tuszynski, J.A., Dogariu, A.

“…The assembly/disassembly of biological macromolecules plays an important role in their biological functionalities. Although the dynamics of tubulin polymers…”
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Regulation of channel function due to physical energetic coupling with a lipid bilayer by Ashrafuzzaman, Md, Tseng, C.-Y., Tuszynski, J.A.

“…•Lipid membrane regulation of membrane protein functions has been addressed.•Energetics behind ion channel-membrane coupling phenomena has been…”
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Analysis of the migration behaviour of single microtubules in electric fields by Stracke, R, Böhm, K.J, Wollweber, L, Tuszynski, J.A, Unger, E

“…By video contrast microscopy, individual microtubules formed from pure tubulin in the presence of taxol were studied in constant electric fields. At nearly…”
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Optomechanical proposal for monitoring microtubule mechanical vibrations by Barzanjeh, Sh, Salari, V, Tuszynski, J A, Cifra, M, Simon, C

“…Microtubules provide the mechanical force required for chromosome separation during mitosis. However, little is known about the dynamic (high-frequency)…”
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Dataset on interactions of membrane active agents with lipid bilayers by Ashrafuzzaman, Md, Tseng, C.-Y., Tuszynski, J.A.

“…We address drug interactions with lipids using in silico simulations and in vitro experiments. The data article provides extended explanations on molecular…”
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Torsional elastic deformations of microtubules within continuous sheet model by Chełminiak, P., Dixon, J. M., Tuszyński, J. A.

“…This paper develops a rigorous analysis of the microtubule elastic deformations in terms of the torsional degrees of freedom using the helix-based cylindrical…”
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Molecular dynamics simulations of tubulin structure and calculations of electrostatic properties of microtubules by Tuszyński, J.A., Brown, J.A., Crawford, E., Carpenter, E.J., Nip, M.L.A., Dixon, J.M., Satarić, M.V.

“…We present the results of molecular dynamics computations based on the atomic resolution structure of tubulin. Values of net charge, charge distribution and…”
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