Search Results - "Tusubira, Deusdedit"

Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer by Preethi, K Auxzilia, Selvakumar, Sushmaa Chandralekha, Ross, Kehinde, Jayaraman, Selvaraj, Tusubira, Deusdedit, Sekar, Durairaj

“…Detecting cancer at an early stage before clinical manifestation could be an effective strategy to decrease cancer mortality. Thus, identifying liquid biopsy…”
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TDP-43 and NEAT long non-coding RNA: Roles in neurodegenerative disease by Sekar, Durairaj, Tusubira, Deusdedit, Ross, Kehinde

“…Understanding and ameliorating neurodegenerative diseases represents a key challenge for supporting the health span of the aging population. Diverse protein…”
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CRISPR/Cas9 and next generation sequencing in the personalized treatment of Cancer by Selvakumar, Sushmaa Chandralekha, Preethi, K Auxzilia, Ross, Kehinde, Tusubira, Deusdedit, Khan, Mohd Wajid Ali, Mani, Panagal, Rao, Tentu Nageswara, Sekar, Durairaj

“…Cancer is caused by a combination of genetic and epigenetic abnormalities. Current cancer therapies are limited due to the complexity of their mechanism,…”
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Corrigendum: TDP-43 and NEAT long non-coding RNA: Roles in neurodegenerative disease by Sekar, Durairaj, Tusubira, Deusdedit, Ross, Kehinde

“…[This corrects the article DOI: 10.3389/fncel.2022.954912.]…”
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Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation by Pettersen, Ina Katrine Nitschke, Tusubira, Deusdedit, Ashrafi, Hanan, Dyrstad, Sissel Elisabeth, Hansen, Lena, Liu, Xiao-Zheng, Nilsson, Linn Iren Hodneland, Løvsletten, Nils Gunnar, Berge, Kjetil, Wergedahl, Hege, Bjørndal, Bodil, Fluge, Øystein, Bruland, Ove, Rustan, Arild Christian, Halberg, Nils, Røsland, Gro Vatne, Berge, Rolf Kristian, Tronstad, Karl Johan

“…Fatty acid oxidation is a central fueling pathway for mitochondrial ATP production. Regulation occurs through multiple nutrient- and energy-sensitive molecular…”
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MicroRNAs in the epigenetic regulation of disease progression in Parkinson’s disease by Selvakumar, Sushmaa Chandralekha, Preethi, K. Auxzilia, Tusubira, Deusdedit, Sekar, Durairaj

“…Parkinson’s disease (PD) is a multifactorial neurodegenerative condition with symptoms such as resting tremor, rigidity, bradykinesia (slowness of moment), and…”
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Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats by Lindquist, Carine, Bjørndal, Bodil, Rossmann, Christine Renate, Tusubira, Deusdedit, Svardal, Asbjørn, Røsland, Gro Vatne, Tronstad, Karl Johan, Hallström, Seth, Berge, Rolf Kristian

“…Hepatic mitochondrial function, APOC-III, and LPL are potential targets for triglyceride (TG)-lowering drugs. After 3 weeks of dietary treatment with the…”
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Dyslipidemia: prevalence and association with precancerous and cancerous lesions of the cervix; a pilot study by Mwangi, Gakii Fridah, Niyonzima, Nixon, Atwine, Raymond, Tusubira, Deusdedit, Mugyenyi, Godfrey R, Ssedyabane, Frank

“…In Sub-Saharan Africa, the prevalence of dyslipidemia is on the rise, with studies showing dyslipidemia as a contributing factor to the progression of…”
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Association between obesity and cervical intraepithelial neoplasia: results from a case control study in south western Uganda by Ssedyabane, Frank, Ngonzi, Joseph, Kajabwangu, Rogers, Najjuma, Josephine Nambi, Tusubira, Deusdedit, Randall, Thomas C

“…Though obesity has been said to be associated with a number of malignancies including cervical cancer, its association with cervical intraepithelial neoplasia…”
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Barriers and facilitators of retention in care after cervical cancer screening: patients' and healthcare providers' perspectives by Owokuhaisa, Judith, Turyakira, Eleanor, Ssedyabane, Frank, Tusubira, Deusdedit, Kajabwangu, Rogers, Musinguzi, Pius, Galiwango, Martin, Randall, Thomas C, Kakongi, Nathan, Castro, Cesar M, Atukunda, Esther C, Maling, Samuel

“…Cervical cancer continues to threaten women's health, especially in low-resource settings. Regular follow-up after screening and treatment is an effective…”
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FOXP3 serum concentration; a likely predictor of CIN and cervical cancer: Secondary analysis from a case control study at a clinic in South western Uganda by Ssedyabane, Frank, Niyonzima, Nixon, Ngonzi, Joseph, Nambi Najjuma, Josephine, Mudondo, Hope, Okeny, Christopher, Nuwashaba, Doreen, Tusubira, Deusdedit

“…•In this study, we determined the association between serum FOXP3 concentration and cervical lesions.•This was a secondary analysis of serum samples from a…”
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Association between serum P16ink4A concentration and CIN and cervical cancer among women attending a cervical cancer clinic in western Uganda: A case control study by Ssedyabane, Frank, Ngonzi, Joseph, Tusubira, Deusdedit, Nambi Najjuma, Josephine, Kajabwangu, Rogers, Okeny, Christopher, Nuwashaba, Doreen, Namuli, Alexcer, Niyonzima, Nixon

“…•We determined the association between serum P16ink4A and cervical lesions.•This was a case control study (90 CIN cases, 90 CC cases and 90 controls).•P16ink4A…”
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A critical review of the limitations of current diagnostic techniques for schistosomiasis by Fasogbon, Ilemobayo Victor, Ondari, Erick Nyakundi, Tusubira, Deusdedit, Ogbonnia, Egwu Chinedu, Ashley, Jon, Sasikumar, Swamiappan, Aja, Patrick Maduabuchi

“…Schistosomiasis is a parasitic disease that is endemic in tropical and subtropical areas. Its diagnosis is crucial for effective treatment and control,…”
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Prevalence, correlates and treatment needs of dental caries in patients attending a diabetic clinic in rural southwestern Uganda: a cross-sectional study by Arubaku, Wilfred, Tusubira, Deusdedit, Ssedyabane, Frank, Chamut, Steffany, Seymour, Brittany Anne, Siedner, Mark J, Niyonzima, Vallence, Nabbanja, Juliet, Kakongi, Nathan, Kwizera, Godfrey, Maling, Samuel

“…Diabetes mellitus is a complex heterogeneous metabolic disorder known to lead to several pathogenic disorders, and has a bidirectional relationship with oral…”
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Comparison of the Nutritional Status of Swiss Albino Mice Fed on Either a Purified or Cereal-Based Diet for 15 weeks by Kinyi, Hellen W., Kato, Charles Drago, Tusubira, Deusdedit, Kiwanuka, Gertrude N.

“…Background. Laboratory animals are commonly fed on cereal-based diets (CBDs) whose nutrient composition is unknown and may confound the metabolic response to…”
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Application of metabolomics to drug discovery and understanding the mechanisms of action of medicinal plants with anti-tuberculosis activity by Tuyiringire, Naasson, Tusubira, Deusdedit, Munyampundu, Jean-Pierre, Tolo, Casim Umba, Muvunyi, Claude M., Ogwang, Patrick Engeu

“…Human tuberculosis (TB) is amongst the oldest and deadliest human bacterial diseases that pose major health, social and economic burden at a global level…”
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Prevalence, correlates and treatment needs of dental caries among people on antiretroviral therapy in Uganda: a cross sectional study by Arubaku, Wilfred, Kwizera, Godfrey, Tusubira, Deusdedit, Kanyesigye, Michael, Chamut, Steffany, Seymour, Brittany Anne, Siedner, Mark J, Niyonzima, Vallence, Najjuma, Josephine N, Maling, Samuel

“…Oral diseases are estimated to affect half of people living with HIV in the western world, and are often marked by pain, discomfort, disfigurement and reduced…”
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High Rate of Loss to Follow-Up Among Patients Undergoing Treatment for Premalignant Cervical Lesions at Mbarara Regional Referral Hospital, Southwestern Uganda: A Retrospective Cohort Study by Kajabwangu, Rogers, Ssedyabane, Frank, Tusubira, Deusdedit, Maling, Samuel, Kakongi, Natthan, Turyakira, Eleanor, Namuli, Alexcer, Galiwango, Martin, Randall, Thomas C

“…Background: For a cervical cancer control program to be effective in reducing the incidence of the disease, there should be high compliance to treatment and…”
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In vitro antimycobacterial activity of medicinal plants Lantana camara, Cryptolepis sanguinolenta, and Zanthoxylum leprieurii by Tuyiringire, Naasson, Taremwa Mugisha, Ivan, Tusubira, Deusdedit, Munyampundu, Jean-Pierre, Mambo Muvunyi, Claude, Vander Heyden, Yvan

“…Imperative need exists to search for new anti-TB drugs that are safer, and more effective against drug-resistant strains. Medicinal plants have been the source…”
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Development of a customized m-Health-based intervention to reduce loss to follow-up among patients undergoing treatment for cervical lesions at a rural referral Hospital, South Western Uganda by Ssedyabane, Frank, Randall, Thomas C., Kajabwangu, Rogers, Namuli, Alexcer, Tusubira, Deusdedit, Kakongi, Nathan, Galiwango, Martin, Maling, Samuel, Turyakira, Eleanor, Atukunda, Esther Cathyln

“…Loss to follow-up (LTFU) in individuals undergoing cervical cancer treatment is a major challenge in many low resource settings. We describe development of a…”
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