Search Results - "Turpin, M P"

Anxiolytic activity of tachykinin NK2 receptor antagonists in the mouse light-dark box by Stratton, S C, Beresford, I J, Harvey, F J, Turpin, M P, Hagan, R M, Tyers, M B

“…The tachykinin NK2 receptor antagonists, GR100679 (0.02-200 micrograms/kg s.c.) and (+/-)-SR489698 (0.05-5.0 micrograms/kg s.c.), dose-dependently increased…”
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Modulation of the rat mesolimbic dopamine pathway by neurokinins by Elliott, P J, Mason, G S, Graham, E A, Turpin, M P, Hagan, R M

“…The locomotor activity (LMA) response induced after infusion of selective neurokinin (NK) agonists into the cell body (A10) and a terminal region of the…”
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Mapping of Dopamine D3 Receptor Binding Site by Pharmacological Characterization of Mutants Expressed in Cho Cells with the Semliki Forest Virus System by Lundstrom, K., Turpin, M. P., Large, C., Robertson, G., Thomas, P., Lewell, X. Q.

“…Abstract Nine mutants and the wild-type human dopamine D3 receptor were expressed at high levels in BHK and CHO cells using the Semliki Forest virus system and…”
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GR159897, a potent non-peptide antagonist at tachykinin NK2 receptors by BERESFORD, I. J. M, SHELDRICK, R. L. G, BALL, D. I, TURPIN, M. P, WALSH, D. M, HAWCOCK, A. B, COLEMAN, R. A, HAGAN, R. M, TYERS, M. B

“…GR159897 ((R)-1-[2-(5-fluoro-1H-indol-3-yl)ethyl]-4-methoxy-4- [(phenylsulfinyl)methyl]piperidine) is a novel, highly potent and selective non-peptide…”
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Proposed schizophrenia-related gene polymorphism: expression of the Ser9Gly mutant human dopamine D3 receptor with the Semliki Forest virus system by Lundstrom, K, Turpin, M P

“…Homozygotes for a BalI polymorphism resulting in the Ser9Gly mutation in the human dopamine D3 receptor gene are suggested to display a twofold higher risk of…”
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Mapping of Dopamine D 3 Receptor Binding Site by Pharmacological Characterization of Mutants Expressed in Cho Cells with the Semliki Forest Virus System by Lundstrom, K., Turpin, M. P., Large, C., Robertson, G., Thomas, P., Lewell, X. Q.

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Novel 6-substituted 2-aminotetralins with potent and selective affinity for the dopamine D3 receptor by Murray, P.J., Helden, R.M., Johnson, M.R., Robertson, G.M., Scopes, D.I.C., Stokes, M., Wadman, S., Whitehead, J.W.F., Hayes, A.G., Kilpatrick, G.J., Large, C., Stubbs, C.M., Turpin, M.P.

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Mapping of dopamine D sub(3) receptor binding site by pharmacological characterization of mutants expressed in CHO cells with the Semliki Forest virus system by Lundstrom, K, Turpin, M P, Large, C, Robertson, G, Thomas, P, Lewell, X-Q

“…Nine mutants and the wild-type human dopamine D sub(3) receptor were expressed at high levels in BHK and CHO cells using the Semliki Forest virus system and…”
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A novel series of arylpiperazines with high affinity and selectivity for the dopamine D 3 receptor by John Murray, P., Harrison, Lee A., Johnson, Martin R., Robertson, Graeme M., Scopes, David I.C., Bull, David R., Graham, Elizabeth A., Hayes, Ann G., Kilpatrick, Gavin J., Daas, Izaak Den, Large, Charles, Sheehan, Michael J., Stubbs, Carole M., Turpin, Michael P.

“…A novel series of arylpiperazines has been synthesised which show high affinity for dopamine D 3 receptors. Several of these compounds exhibit ca. 100 fold…”
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Novel 6-substituted 2-aminotetralins with potent and selective affinity for the dopamine D 3 receptor by Murray, P.J., Helden, R.M., Johnson, M.R., Robertson, G.M., Scopes, D.I.C., Stokes, M., Wadman, S., Whitehead, J.W.F., Hayes, A.G., Kilpatrick, G.J., Large, C., Stubbs, C.M., Turpin, M.P.

“…Starting from (1S,2R)-5-methoxy-1-methyl-2- N, N-dipropylaminotetralin [(+)-UH-232] as a lead structure, a series of novel 6-substituted 2-aminotetralins have…”
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