Search Results - "Turner, Sara M.F"
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Neuropathology in respiratory-related motoneurons in young Pompe ( Gaa−/− ) mice
Published in Respiratory physiology & neurobiology (15-06-2016)“…Highlights • Brainstem and spinal cord neuropathology was studied in young asymptomatic Pompe ( Gaa−/− ) mice. • Overt histopathology and glycogen accumulation…”
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Abrupt changes in pentobarbital sensitivity in preBötzinger complex region, hypoglossal motor nucleus, nucleus tractus solitarius , and cortex during rat transitional period (P10–P15)
Published in Respiratory physiology & neurobiology (01-02-2015)“…Highlights • Pentobarbital sensitivity changed during P10–P15 in rat medullary and cortical slices. • Pentobarbital resistance in preBötC-region neurons…”
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AAV Gene Therapy Utilizing Glycosylation-Independent Lysosomal Targeting Tagged GAA in the Hypoglossal Motor System of Pompe Mice
Published in Molecular therapy. Methods & clinical development (13-12-2019)“…Pompe disease is caused by mutations in the gene encoding the lysosomal glycogen-metabolizing enzyme, acid-alpha glucosidase (GAA). Tongue myofibers and…”
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Hyperbaric Oxygen Therapy after Mid-Cervical Spinal Contusion Injury
Published in Journal of neurotrauma (01-05-2022)“…Hyperbaric oxygen (HBO) therapy is frequently used to treat peripheral wounds or decompression sickness. Evidence suggests that HBO therapy can provide…”
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Anatomy and physiology of phrenic afferent neurons
Published in Journal of neurophysiology (01-12-2017)“…Large-diameter myelinated phrenic afferents discharge in phase with diaphragm contraction, and smaller diameter fibers discharge across the respiratory cycle…”
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Automated Gait Analysis Through Hues and Areas (AGATHA): A Method to Characterize the Spatiotemporal Pattern of Rat Gait
Published in Annals of biomedical engineering (01-03-2017)“…While rodent gait analysis can quantify the behavioral consequences of disease, significant methodological differences exist between analysis platforms and…”
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Comparison of treatment efficacy in the hypoglossal motor system of AAV‐DES‐coGAA and novel vector AAV‐DES‐IGFIIcoGAA in Gaa −/− mice
Published in The FASEB journal (01-04-2017)“…Abstract only Pompe disease is a neuromuscular disorder characterized by a systemic lack of the glycogen metabolizing enzyme acid‐alpha glucosidase. The result…”
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Comparison of Hypoglossal Motoneuron Transgene Expression following Single vs Dual Tongue Injection of AAV9‐CBA‐GFP
Published in The FASEB journal (01-04-2016)“…Abstract only Retrograde transport of viral vectors following intramuscular injection allows for targeted gene delivery to motoneuron pools. Gene delivery to…”
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Power spectral analysis of hypoglossal nerve activity during intermittent hypoxia-induced long-term facilitation in mice
Published in Journal of neurophysiology (01-03-2016)“…Power spectral analyses of electrical signals from respiratory nerves reveal prominent oscillations above the primary rate of breathing. Acute exposure to…”
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Protecting motor networks during perinatal ischemia: the case for delta-opioid receptors
Published in Annals of the New York Academy of Sciences (01-06-2010)“…Perinatal ischemia is a common clinical problem with few successful therapies to prevent neuronal damage. Delta opioid receptor (DOR) activation is a…”
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