Search Results - "Turner, Russell T"

Influence of body weight on bone mass, architecture and turnover by Iwaniec, Urszula T, Turner, Russell T

“…Weight-dependent loading of the skeleton plays an important role in establishing and maintaining bone mass and strength. This review focuses on mechanical…”
Get full text

Peripheral leptin regulates bone formation by Turner, Russell T, Kalra, Satya P, Wong, Carmen P, Philbrick, Kenneth A, Lindenmaier, Laurence B, Boghossian, Stephane, Iwaniec, Urszula T

“…Substantial evidence does not support the prevailing view that leptin, acting through a hypothalamic relay, decreases bone accrual by inhibiting bone…”
Get full text

Ethanol consumption in non-human primates alters plasma markers of bone turnover but not tibia architecture by Zhakubayev, Alibek, Sattgast, Lara H., Lewis, Anne D., Grant, Kathleen A., Turner, Russell T., Iwaniec, Urszula T., Benton, Mary Lauren

“…Ethanol consumption is associated with positive, negative, and neutral effects on the skeletal system. Our previous work using a nonhuman primate model of…”
Get full text

Bone Marrow Adipose Tissue Is Not Required for Reconstitution of the Immune System Following Irradiation in Male Mice by Keune, Jessica A, Wong, Carmen P, Branscum, Adam J, Menn, Scott A, Iwaniec, Urszula T, Turner, Russell T

“…Bone marrow adipose tissue (BMAT) is hypothesized to serve as an expandable/contractible fat depot which functions, in part, to minimize energy requirements…”
Get full text

Long-duration leptin transgene expression in dorsal vagal complex does not alter bone parameters in female Sprague Dawley rats by Turner, Russell T., Branscum, Adam J., Iwaniec, Urszula T.

“…The hypothalamus and dorsal vagal complex (DVC) are both important for integration of signals that regulate energy balance. Increased leptin transgene…”
Get full text

Brown adipose tissue but not tibia exhibits a dramatic response to acute reduction in environmental temperature in growing male mice by Wong, Carmen P., Iwaniec, Urszula T., Turner, Russell T.

“…Mice are typically housed at room temperature (∼22 °C), which is well below their thermoneutral zone and results in cold stress. Chronic cold stress leads to…”
Get full text

Caloric Restriction and Hypothalamic Leptin Gene Therapy Have Differential Effects on Energy Partitioning in Adult Female Rats by Turner, Russell T., Wong, Carmen P., Fosse, Kristina M., Branscum, Adam J., Iwaniec, Urszula T.

“…Dieting is a common but often ineffective long-term strategy for preventing weight gain. Similar to humans, adult rats exhibit progressive weight gain. The…”
Get full text

Effects of Spaceflight on Bone Microarchitecture in the Axial and Appendicular Skeleton in Growing Ovariectomized Rats by Keune, Jessica A., Branscum, Adam J., Iwaniec, Urszula T., Turner, Russell T.

“…This study investigated the effects of a 14-day spaceflight on bone mass, density and microarchitecture in weight bearing (femur and humerus) and non-weight…”
Get full text

Leptin and environmental temperature as determinants of bone marrow adiposity in female mice by Turner, Russell T., Nesser, Kira L., Philbrick, Kenneth A., Wong, Carmen P., Olson, Dawn A., Branscum, Adam J., Iwaniec, Urszula T.

“…Bone marrow adipose tissue (BMAT) levels are higher in distal femur metaphysis of female mice housed at thermoneutral (32°C) than in mice housed at 22°C, as…”
Get full text

MicroRNAs control neurobehavioral development and function in zebrafish by Tal, Tamara L., Franzosa, Jill A., Tilton, Susan C., Philbrick, Kenneth A., Iwaniec, Urszula T., Turner, Russell T., Waters, Katrina M., Tanguay, Robert L.

“…microRNAs (miRNAs) have emerged as regulators of a broad spectrum of neurodevelopmental processes, including brain morphogenesis, neuronal differentiation, and…”
Get full text

Effect of Leptin Deficiency on the Skeletal Response to Hindlimb Unloading in Adult Male Mice by Keune, Jessica A., Branscum, Adam J., Wong, Carmen P., Iwaniec, Urszula T., Turner, Russell T.

“…Based on body weight, morbidly obese leptin-deficient ob/ob mice have less bone than expected, suggesting that leptin plays a role in the skeletal response to…”
Get full text

Effects of hypothalamic leptin gene therapy on osteopetrosis in leptin-deficient mice by Philbrick, Kenneth A, Martin, Stephen A, Colagiovanni, Amy R, Branscum, Adam J, Turner, Russell T, Iwaniec, Urszula T

“…Impaired resorption of cartilage matrix deposited during endochondral ossification is a defining feature of juvenile osteopetrosis. Growing, leptin-deficient…”
Get full text

Dietary licorice root supplementation reduces diet‐induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland by Madak‐Erdogan, Zeynep, Gong, Ping, Zhao, Yiru Chen, Xu, Liwen, Wrobel, Kinga U, Hartman, James A, Wang, Michelle, Cam, Anthony, Iwaniec, Urszula T, Turner, Russell T, Twaddle, Nathan C, Doerge, Daniel R, Khan, Ikhlas A, Katzenellenbogen, John A, Katzenellenbogen, Benita S, Helferich, William G

“…SCOPE: We studied the impact of dietary supplementation with licorice root components on diet‐induced obesity, fat accumulation, and hepatic steatosis in…”
Get full text

Growth hormone regulates the balance between bone formation and bone marrow adiposity by Menagh, Philip J, Turner, Russell T, Jump, Donald B, Wong, Carmen P, Lowry, Malcolm B, Yakar, Shoshana, Rosen, Clifford J, Iwaniec, Urszula T

“…Cancellous bone decreases and bone marrow fat content increases with age. Osteoblasts and adipocytes are derived from a common precursor, and growth hormone…”
Get full text

Effects of Propranolol on Bone, White Adipose Tissue, and Bone Marrow Adipose Tissue in Mice Housed at Room Temperature or Thermoneutral Temperature by Turner, Russell T, Philbrick, Kenneth A, Wong, Carmen P, Gamboa, Amanda R, Branscum, Adam J, Iwaniec, Urszula T

“…Growing female mice housed at room temperature (22°C) weigh the same but differ in body composition compared to mice housed at thermoneutrality (32°C)…”
Get full text

Evidence for increased thermogenesis in female C57BL/6J mice housed aboard the international space station by Wong, Carmen P., Iwaniec, Urszula T., Turner, Russell T.

“…Sixteen-week-old female C57BL/6J mice were sacrificed aboard the International Space Station after 37 days of flight (RR-1 mission) and frozen carcasses…”
Get full text

Validating Causal Diagrams of Human Health Risks for Spaceflight: An Example Using Bone Data from Rodents by Reynolds, Robert J, Scott, Ryan T, Turner, Russell T, Iwaniec, Urszula T, Bouxsein, Mary L, Sanders, Lauren M, Antonsen, Erik L

“…As part of the risk management plan for human system risks at the US National Aeronautics and Space Administration (NASA), the NASA Human Systems Risk Board…”
Get full text

Skeletal Response to Alcohol by Turner, Russell T.

“…: This review briefly assesses the well‐established effects of alcohol consumption on bone and mineral metabolism and addresses areas of controversy that need…”
Get full text

Hypothalamic Leptin Gene Therapy Reduces Bone Marrow Adiposity in ob/ob Mice Fed Regular and High-Fat Diets by Lindenmaier, Laurence B, Philbrick, Kenneth A, Branscum, Adam J, Kalra, Satya P, Turner, Russell T, Iwaniec, Urszula T

“…Low bone mass is often associated with elevated bone marrow adiposity. Since osteoblasts and adipocytes are derived from the same mesenchymal stem cell (MSC)…”
Get full text

Low dose parathyroid hormone maintains normal bone formation in adult male rats during rapid weight loss by Turner, Russell T, Iwaniec, Urszula T

“…Abstract A persistent negative energy balance results in bone loss. It is not clear whether the bone loss associated with chronic negative energy balance can…”
Get full text