Search Results - "Turner, Kenneth"
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GGR Handbook of Rock and Mineral Analysis Chapter 6 (Part 1) Principles and Practice of X‐Ray Fluorescence Spectrometry –1: Fundamentals of XRF and Matrix Corrections
Published in Geostandards and geoanalytical research (01-09-2024)“…This chapter (Principles and Practice of X‐Ray Fluorescence Spectrometry – 1: Fundamentals of XRF and Matrix Corrections) is a contribution to the Geostandards…”
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REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19
Published in The New England journal of medicine (21-01-2021)“…An anti–SARS-CoV-2 antibody cocktail was given to patients within 3 days after PCR confirmation of Covid-19. In patients who were antibody-negative at…”
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REGEN-COV Antibody Combination and Outcomes in Outpatients with Covid-19
Published in The New England journal of medicine (02-12-2021)“…This phase 3, placebo-controlled platform trial evaluated a single infusion of casirivimab and imdevimab (REGEN-COV) at 2400-mg and 1200-mg doses in…”
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Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19
Published in The New England journal of medicine (23-09-2021)“…Household contacts of persons infected with SARS-CoV-2 are at risk for infection. A single subcutaneous injection of two anti–SARS-CoV-2 monoclonal antibodies…”
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At the mercy of myself: A thematic analysis of beliefs about losing control
Published in Psychology and psychotherapy (01-06-2024)“…Purpose Concerns about the likelihood, consequences, and meaning of losing control are commonplace across anxiety‐related disorders. However, several…”
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Effect of Subcutaneous Casirivimab and Imdevimab Antibody Combination vs Placebo on Development of Symptomatic COVID-19 in Early Asymptomatic SARS-CoV-2 Infection: A Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (01-02-2022)“…IMPORTANCE: Easy-to-administer anti–SARS-CoV-2 treatments may be used to prevent progression from asymptomatic infection to symptomatic disease and to reduce…”
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Population Pharmacokinetics of Casirivimab and Imdevimab in Pediatric and Adult Non-Infected Individuals, Pediatric and Adult Ambulatory or Hospitalized Patients or Household Contacts of Patients Infected with SARS-COV-2
Published in Pharmaceutical research (01-10-2024)“…Introduction Casirivimab (CAS) and imdevimab (IMD) are two fully human monoclonal antibodies that bind different epitopes on the receptor binding domain of…”
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Examining protective effects of SARS-CoV-2 neutralizing antibodies after vaccination or monoclonal antibody administration
Published in Nature communications (17-06-2023)“…While new vaccines for SARS-CoV-2 are authorized based on neutralizing antibody (nAb) titer against emerging variants of concern, an analogous pathway does not…”
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Casirivimab and Imdevimab for the Treatment of Hospitalized Patients With COVID-19
Published in The Journal of infectious diseases (28-12-2022)“…The open-label RECOVERY study reported improved survival in hospitalized, SARS-CoV-2 seronegative patients treated with casirivimab and imdevimab (CAS + IMD)…”
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An open-label study to estimate the effect of steady-state erythromycin on the pharmacokinetics, pharmacodynamics, and safety of a single dose of rivaroxaban in subjects with renal impairment and normal renal function
Published in Journal of clinical pharmacology (01-12-2014)“…Two previously conducted rivaroxaban studies showed that, separately, renal impairment (RI) and concomitant administration of erythromycin (P‐glycoprotein and…”
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Efficacy and safety of a single dose of casirivimab and imdevimab for the prevention of COVID-19 over an 8-month period: a randomised, double-blind, placebo-controlled trial
Published in The Lancet infectious diseases (01-10-2022)“…There is an unmet need for COVID-19 prevention in patient populations who have not mounted or are not expected to mount an adequate immune response to complete…”
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Systemic exposure to aflibercept after intravitreal injection in premature neonates with retinopathy of prematurity: results from the FIREFLEYE randomized phase 3 study
Published in Eye (London) (01-06-2024)“…Background There are no data on pharmacokinetics, pharmacodynamics, and immunogenicity of intravitreal aflibercept in preterm infants with retinopathy of…”
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Repeat subcutaneous administration of casirivimab and imdevimab in adults is well-tolerated and prevents the occurrence of COVID-19
Published in International journal of infectious diseases (01-09-2022)“…•Phase 1 study assessed monthly casirivimab+imdevimab (CAS+IMD) in uninfected adults•Repeat monthly CAS+IMD (1200 mg subcutaneously [SC]) was well-tolerated,…”
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Policy conflicts in home automation
Published in Computer networks (Amsterdam, Netherlands : 1999) (20-08-2013)“…The nature of home automation is introduced. It is argued that end users should be able to define how the home system reacts to changing circumstances…”
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Assessing the safety and pharmacokinetics of casirivimab and imdevimab (CAS+IMD) in a cohort of pregnant outpatients with COVID-19: results from an adaptive, multicentre, randomised, double-blind, phase 1/2/3 study
Published in BMJ open (08-10-2024)“…ObjectivePregnant women with COVID-19 are at elevated risk for severe outcomes, but clinical data on management of these patients are limited. Monoclonal…”
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In vitro analysis of the anthelmintic activity of forage chicory (Cichorium intybus L.) sesquiterpene lactones against a predominantly Haemonchus contortus egg population
Published in Veterinary parasitology (25-08-2011)“…The anthelmintic activity of chicory (Cichorium intybus L.) herbage has been attributed to sesquiterpene lactones. Chicory leaves contain significant amounts…”
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Population Pharmacokinetics of Fasinumab in Healthy Volunteers and Patients With Pain Due to Osteoarthritis of the Knee or Hip
Published in Clinical pharmacology in drug development (01-06-2024)“…Osteoarthritis (OA) pain management options are currently limited. Fasinumab, an anti‐nerve growth factor monoclonal antibody, has been investigated in healthy…”
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REGEN-COV ® antibody cocktail bioanalytical strategy: comparison of LC-MRM-MS and immunoassay methods for drug quantification
Published in Bioanalysis (01-12-2021)“…In response to the COVID-19 pandemic, Regeneron developed the anti-SARS-CoV-2 monoclonal antibody cocktail, REGEN-COV (RONAPREVE outside the USA). Drug…”
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COVID-19 prevention with subcutaneous administration of the monoclonal antibodies casirivimab and imdevimab: Subgroup analysis in participants with cardiovascular disease and diabetes
Published in The American heart journal (01-12-2021)“…In a Phase 3 prevention trial, the monoclonal antibody combination casirivimab and imdevimab (REGEN-COVTM) administered subcutaneously (SC) prevented…”
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