Search Results - "Turner, James A"

Performance Improvement and Artificial Intelligence (AI) Emerge to Bridge the Gap for Exceptional Gastroenterology Physician Onboarding by Rudnick, John D., Back, Michael J., Turner, James A., Vezina, Michelle L.

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Meiotic sex chromosome inactivation by Turner, James M A

“…X chromosome inactivation is most commonly studied in the context of female mammalian development, where it performs an essential role in dosage compensation…”
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Advances and challenges in genetic technologies to produce single-sex litters by Douglas, Charlotte, Turner, James M. A

“…There is currently a requirement for single-sex litters for many applications, including agriculture, pest control, and reducing animal culling in line with…”
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CRISPR-Cas9 effectors facilitate generation of single-sex litters and sex-specific phenotypes by Douglas, Charlotte, Maciulyte, Valdone, Zohren, Jasmin, Snell, Daniel M., Mahadevaiah, Shantha K., Ojarikre, Obah A., Ellis, Peter J. I., Turner, James M. A.

“…Animals are essential genetic tools in scientific research and global resources in agriculture. In both arenas, a single sex is often required in surplus. The…”
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IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche by Wamaitha, Sissy E., Grybel, Katarzyna J., Alanis-Lobato, Gregorio, Gerri, Claudia, Ogushi, Sugako, McCarthy, Afshan, Mahadevaiah, Shantha K., Healy, Lyn, Lea, Rebecca A., Molina-Arcas, Miriam, Devito, Liani G., Elder, Kay, Snell, Phil, Christie, Leila, Downward, Julian, Turner, James M. A., Niakan, Kathy K.

“…Our understanding of the signalling pathways regulating early human development is limited, despite their fundamental biological importance. Here, we mine…”
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Four Core Genotypes mice harbour a 3.2MB X-Y translocation that perturbs Tlr7 dosage by Panten, Jasper, Del Prete, Stefania, Cleland, James P., Saunders, Lauren M., van Riet, Job, Schneider, Anja, Ginno, Paul, Schneider, Nina, Koch, Marie-Luise, Chen, Xuqi, Gerstung, Moritz, Stegle, Oliver, Arnold, Arthur P., Turner, James M. A., Heard, Edith, Odom, Duncan T.

“…The Four Core Genotypes (FCG) is a mouse model system used to disentangle the function of sex chromosomes and hormones. We report that a copy of a 3.2 MB…”
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DNA damage response protein TOPBP1 regulates X chromosome silencing in the mammalian germ line by ElInati, Elias, Russell, Helen R., Ojarikre, Obah A., Sangrithi, Mahesh, Hirota, Takayuki, de Rooij, Dirk G., McKinnon, Peter J., Turner, James M. A.

“…Meiotic synapsis and recombination between homologs permits the formation of cross-overs that are essential for generating chromosomally balanced sperm and…”
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Valuing biodiversity enhancement in New Zealand's planted forests: Socioeconomic and spatial determinants of willingness-to-pay by Yao, Richard T., Scarpa, Riccardo, Turner, James A., Barnard, Tim D., Rose, John M., Palma, João H.N., Harrison, Duncan R.

“…Planted forests are increasingly recognised for the provision of habitats for species threatened with extinction. Despite this development, a limited number of…”
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The slugs of Britain and Ireland: undetected and undescribed species increase a well-studied, economically important fauna by more than 20 by Rowson, Ben, Anderson, Roy, Turner, James A, Symondson, William O C

“…The slugs of Britain and Ireland form a well-studied fauna of economic importance. They include many widespread European species that are introduced elsewhere…”
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The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes by ElInati, Elias, Zielinska, Agata P., McCarthy, Afshan, Kubikova, Nada, Maciulyte, Valdone, Mahadevaiah, Shantha, Sangrithi, Mahesh N., Ojarikre, Obah, Wells, Dagan, Niakan, Kathy K., Schuh, Melina, Turner, James M. A.

“…DNA double-strand breaks (DSBs) are toxic to mammalian cells. However, during meiosis, more than 200 DSBs are generated deliberately, to ensure reciprocal…”
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The mouse X chromosome is enriched for multicopy testis genes showing postmeiotic expression by Mueller, Jacob L, Turner, James M A, Mahadevaiah, Shantha K, Park, Peter J, Warburton, Peter E, Page, David C

“…According to the prevailing view, mammalian X chromosomes are enriched in spermatogenesis genes expressed before meiosis and deficient in spermatogenesis genes…”
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Histone H2AFX Links Meiotic Chromosome Asynapsis to Prophase I Oocyte Loss in Mammals by Cloutier, Jeffrey M, Mahadevaiah, Shantha K, ElInati, Elias, Nussenzweig, André, Tóth, Attila, Turner, James M A

“…Chromosome abnormalities are common in the human population, causing germ cell loss at meiotic prophase I and infertility. The mechanisms driving this loss are…”
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Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation by Grant, Jennifer, Mahadevaiah, Shantha K., Khil, Pavel, Sangrithi, Mahesh N., Royo, Hélène, Duckworth, Janine, McCarrey, John R., VandeBerg, John L., Renfree, Marilyn B., Taylor, Willie, Elgar, Greg, Camerini-Otero, R. Daniel, Gilchrist, Mike J., Turner, James M. A.

“…A non-coding RNA termed Rsx , which has properties consistent with a role in X-chromosome inactivation, is identified in the marsupial Monodelphis domestica …”
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Priorities for science to overcome hurdles thwarting the full promise of the ‘digital agriculture’ revolution by Shepherd, Mark, Turner, James A, Small, Bruce, Wheeler, David

“…The world needs to produce more food, more sustainably, on a planet with scarce resources and under changing climate. The advancement of technologies,…”
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Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis by Fukuda, Tomoyuki, Pratto, Florencia, Schimenti, John C, Turner, James M A, Camerini-Otero, R Daniel, Höög, Christer

“…Meiotic recombination and chromosome synapsis between homologous chromosomes are essential for proper chromosome segregation at the first meiotic division…”
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Silencing of X-Linked MicroRNAs by Meiotic Sex Chromosome Inactivation by Royo, Hélène, Seitz, Hervé, ElInati, Elias, Peters, Antoine H F M, Stadler, Michael B, Turner, James M A

“…During the pachytene stage of meiosis in male mammals, the X and Y chromosomes are transcriptionally silenced by Meiotic Sex Chromosome Inactivation (MSCI)…”
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Discovery to Development: Insecticides for Malaria Vector Control by Turner, James A, Ruscoe, Colin N E, Perrior, Trevor R

“…This report provides an outline of a program for the discovery of new public health insecticides for malaria vector control. The status of malaria vector…”
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Genome editing reveals a role for OCT4 in human embryogenesis by Fogarty, Norah M. E., McCarthy, Afshan, Snijders, Kirsten E., Powell, Benjamin E., Kubikova, Nada, Blakeley, Paul, Lea, Rebecca, Elder, Kay, Wamaitha, Sissy E., Kim, Daesik, Maciulyte, Valdone, Kleinjung, Jens, Kim, Jin-Soo, Wells, Dagan, Vallier, Ludovic, Bertero, Alessandro, Turner, James M. A., Niakan, Kathy K.

“…Despite their fundamental biological and clinical importance, the molecular mechanisms that regulate the first cell fate decisions in the human embryo are not…”
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Error-prone ZW pairing and no evidence for meiotic sex chromosome inactivation in the chicken germ line by Guioli, Silvana, Lovell-Badge, Robin, Turner, James M A

“…In the male mouse the X and Y chromosomes pair and recombine within the small pseudoautosomal region. Genes located on the unsynapsed segments of the X and Y…”
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Where to for collaboration in land and water policy development in Aotearoa New Zealand? Guidance for authorising agencies by Kirk, Nicholas, Robson-Williams, Melissa, Bammer, Gabriele, Foote, Jeff, Butcher, Lian, Deans, Neil, Harmsworth, Garth, Hepi, Maria, Lilburne, Linda, Nicholas, Barbara, Small, Bruce, Turner, James A., Young, Justine

“…For the past decade, collaboration has been the preferred method of devising land and water policy in Aotearoa New Zealand to achieve agreed outcomes. However,…”
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