Search Results - "Turner, Emma M"
-
1
Evaluation and initial in vitro and ex vivo characterization of the potential positron emission tomography ligand, BU99008 (2-(4,5-Dihydro-1H-imidazol-2-yl)-1- methyl-1H-indole), for the imidazoline2 binding site
Published in Synapse (New York, N.Y.) (01-06-2012)“…The density of the Imidazoline2 binding site (I2BS) has been shown to change in psychiatric conditions such as depression and addiction, along with…”
Get full text
Journal Article -
2
Selectivity and Anti-Parkinson’s Potential of Thiadiazolidinone RGS4 Inhibitors
Published in ACS chemical neuroscience (17-06-2015)“…Many current therapies target G protein coupled receptors (GPCR), transporters, or ion channels. In addition to directly targeting these proteins, disrupting…”
Get full text
Journal Article -
3
Small Molecule Inhibitors of Regulators of G Protein Signaling (RGS) Proteins
Published in ACS medicinal chemistry letters (09-02-2012)“…Recently, regulators of G protein signaling (RGS) proteins have emerged as potential therapeutic targets since they provide an alternative method of modulating…”
Get full text
Journal Article -
4
Imaging Imidazoline-I^sub 2^ Binding Sites in Porcine Brain Using ^sup 11^C-BU99008
Published in The Journal of nuclear medicine (1978) (01-01-2013)“…Changes in the density of imidazoline-... binding sites have been observed in a range of neurologic disorders including Alzheimer's disease, Huntington's…”
Get full text
Journal Article -
5
Imaging Imidazoline-I 2 Binding Sites in Porcine Brain Using 11 C-BU99008
Published in Journal of Nuclear Medicine (01-01-2013)Get full text
Journal Article -
6
Evaluation and initial in vitro and ex vivo characterization of the potential positron emission tomography ligand, BU99008 (2‐(4,5‐Dihydro‐1 H ‐imidazol‐2‐yl)‐1‐ methyl‐1 H ‐indole), for the imidazoline 2 binding site
Published in Synapse (New York, N.Y.) (01-06-2012)“…The density of the Imidazoline 2 binding site (I 2 BS) has been shown to change in psychiatric conditions such as depression and addiction, along with…”
Get full text
Journal Article -
7
Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins
Published in ACS medicinal chemistry letters (09-02-2012)“…Recently regulators of G protein signalling (RGS) proteins have emerged as potential therapeutic targets since they provide an alternative method of modulating…”
Get full text
Journal Article -
8
Imaging imidazoline-I2 binding sites in porcine brain using 11C-BU99008
Published in The Journal of nuclear medicine (1978) (01-01-2013)“…Changes in the density of imidazoline-I(2) binding sites have been observed in a range of neurologic disorders including Alzheimer's disease, Huntington's…”
Get full text
Journal Article