Search Results - "Turner, Alexandra P"

Deep phenotyping of the lipidomic response in COVID‐19 and non‐COVID‐19 sepsis by Meng, Hu, Sengupta, Arjun, Ricciotti, Emanuela, Mrčela, Antonijo, Mathew, Divij, Mazaleuskaya, Liudmila L., Ghosh, Soumita, Brooks, Thomas G., Turner, Alexandra P., Schanoski, Alessa Soares, Lahens, Nicholas F., Tan, Ai Wen, Woolfork, Ashley, Grant, Greg, Susztak, Katalin, Letizia, Andrew G., Sealfon, Stuart C., Wherry, E. John, Laudanski, Krzysztof, Weljie, Aalim M., Meyer, Nuala J., FitzGerald, Garret A.

“…Background Lipids may influence cellular penetrance by viral pathogens and the immune response that they evoke. We deeply phenotyped the lipidomic response to…”
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Extended distal pancreatectomy for pancreatic adenocarcinoma with splenic vein thrombosis and/or adjacent organ invasion by Roch, Alexandra M., M.D., M.S, Singh, Harjot, M.D, Turner, Alexandra P., M.D, Ceppa, Eugene P., M.D, House, Michael G., M.D, Zyromski, Nicholas J., M.D, Nakeeb, Attila, M.D, Schmidt, Christian Max, M.D., Ph.D., M.B.A

“…Abstract Background Patients with adenocarcinoma of the pancreatic body/tail and associated vascular thrombosis or adjacent organ invasion are suboptimal…”
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Validating a Proteomic Signature of Severe COVID-19 by Cosgriff, Christopher V, Miano, Todd A, Mathew, Divij, Huang, Alexander C, Giannini, Heather M, Kuri-Cervantes, Leticia, Pampena, M Betina, Ittner, Caroline A G, Weisman, Ariel R, Agyekum, Roseline S, Dunn, Thomas G, Oniyide, Oluwatosin, Turner, Alexandra P, D'Andrea, Kurt, Adamski, Sharon, Greenplate, Allison R, Anderson, Brian J, Harhay, Michael O, Jones, Tiffanie K, Reilly, John P, Mangalmurti, Nilam S, Shashaty, Michael G S, Betts, Michael R, Wherry, E John, Meyer, Nuala J

“…COVID-19 is a heterogenous disease. Biomarker-based approaches may identify patients at risk for severe disease, who may be more likely to benefit from…”
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mTOR regulates memory CD8 T-cell differentiation by Ahmed, Rafi, Araki, Koichi, Turner, Alexandra P, Shaffer, Virginia Oliva, Gangappa, Shivaprakash, Keller, Susanne A, Bachmann, Martin F, Larsen, Christian P

“…Memory CD8 T cells are a critical component of protective immunity, and inducing effective memory T-cell responses is a major goal of vaccines against chronic…”
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Association of vancomycin plus piperacillin–tazobactam with early changes in creatinine versus cystatin C in critically ill adults: a prospective cohort study by Miano, Todd A., Hennessy, Sean, Yang, Wei, Dunn, Thomas G., Weisman, Ariel R., Oniyide, Oluwatosin, Agyekum, Roseline S., Turner, Alexandra P., Ittner, Caroline A. G., Anderson, Brian J., Wilson, F. Perry, Townsend, Raymond, Reilly, John P., Giannini, Heather M., Cosgriff, Christopher V., Jones, Tiffanie K., Meyer, Nuala J., Shashaty, Michael G. S.

“…Purpose Although dozens of studies have associated vancomycin + piperacillin–tazobactam with increased acute kidney injury (AKI) risk, it is unclear whether…”
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The Role of Implicit Bias in Surgical Resident Evaluations by Dill-Macky, Arabella, Hsu, Chiu-Hsieh, Neumayer, Leigh A., Nfonsam, Valentine N., Turner, Alexandra P.

“…Implicit bias is a key factor preventing the advancement and retention of women and underrepresented minorities in academic surgery. We examined the role of…”
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Induction immunosuppression in liver transplantation: a review by Turner, Alexandra P, Knechtle, Stuart J

“…Antibody therapy for induction is seldom used in liver transplantation in the United States, but continues to be used in approximately 10% of patients. The…”
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Acute Respiratory Distress Syndrome Mediates the Association between Early Plasma Soluble Receptor for Advanced Glycation End Products Concentrations and Mortality in Sepsis by Jones, Tiffanie K, Reilly, John P, Anderson, Brian J, Miano, Todd A, Dunn, Thomas G, Turner, Alexandra P, Agyekum, Roseline S, Feng, Rui, Ittner, Caroline A G, Shashaty, Michael G S, Meyer, Nuala J

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Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates by Agarwal, Avinash, Russell, Maria, Leopardi, Frank V, Charafeddine, Ali H, Turner, Alexandra P, Song, Mingqing, Kirk, Allan D, Stempora, Linda, Kampen, Robert L, Larsen, Christian P, Weaver, Tim A

“…Memory T cells promote allograft rejection particularly in co-stimulation blockade-based immunosuppressive regimens. Here we show that the CD2-specific fusion…”
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Patients’ Perspectives on Life and Recovery 1 Year After COVID-19 Hospitalization by Chow, Carolyn P., Chesley, Christopher F., Ward, Michaela, Neergaard, Rebecca, Prasad, Taara V., Dress, Erich M., Reagan, Sara, Kalyani, Priyanka, Smyk, Nathan, Turner, Alexandra P., Agyekum, Roseline S., Ittner, Caroline A. G., Sandsmark, Danielle K., Meyer, Nuala J., Harhay, Michael O., Kohn, Rachel, Auriemma, Catherine L.

“…Background Many patients hospitalized for COVID-19 experience prolonged symptoms months after discharge. Little is known abou t patients’ personal experiences…”
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LFA-1-specific therapy prolongs allograft survival in rhesus macaques by Badell, Idelberto R, Russell, Maria C, Thompson, Peter W, Turner, Alexandra P, Weaver, Tim A, Robertson, Jennifer M, Avila, Jose G, Cano, Jose A, Johnson, Brandi E, Song, Mingqing, Leopardi, Frank V, Swygert, Sarah, Strobert, Elizabeth A, Ford, Mandy L, Kirk, Allan D, Larsen, Christian P

“…Outcomes in transplantation have been limited by suboptimal long-term graft survival and toxicities associated with current immunosuppressive approaches. T…”
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Cytometry masked autoencoder: An accurate and interpretable automated immunophenotyper by Kim, Jaesik, Ionita, Matei, Lee, Matthew, McKeague, Michelle L., Pattekar, Ajinkya, Painter, Mark M., Wagenaar, Joost, Truong, Van, Norton, Dylan T., Mathew, Divij, Nam, Yonghyun, Apostolidis, Sokratis A., Clendenin, Cynthia, Orzechowski, Patryk, Jung, Sang-Hyuk, Woerner, Jakob, Ittner, Caroline A.G., Turner, Alexandra P., Esperanza, Mika, Dunn, Thomas G., Mangalmurti, Nilam S., Reilly, John P., Meyer, Nuala J., Calfee, Carolyn S., Liu, Kathleen D., Matthy, Michael A., Swigart, Lamorna Brown, Burnham, Ellen L., McKeehan, Jeffrey, Gandotra, Sheetal, Russel, Derek W., Gibbs, Kevin W., Thomas, Karl W., Barot, Harsh, Greenplate, Allison R., Wherry, E. John, Kim, Dokyoon

“…Single-cell cytometry data are crucial for understanding the role of the immune system in diseases and responses to treatment. However, traditional methods for…”
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Mo1621 Socioeconomic Status and Surgical Outcomes After Regional Pancreatectomy by Schmidt, Heidi, Valsangkar, Nakul, Kilbane, E. Molly, Turner, Alexandra P, House, Michael G, Zyromski, Nicholas J, Nakeeb, Attila, Schmidt, C. Max, Ceppa, Eugene P

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A novel calcineurin inhibitor– and sirolimus-free anti-LFA-1-based therapy enhances allogeneic islet survival and function in nonhuman primates by Badell, Idelberto R., MD, Turner, Alexandra P., MD, Cano, Jose A., BS, Avila, Jose G., MD, PhD, Johnson, Brandi E., BS, Leopardi, Frank V., BS, Swygert, Sarah G., BS, Strobert, Elizabeth A., DVM, Kirk, Allan D., MD, PhD, FACS, Larsen, Christian P., MD, PhD

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Genome-Wide Association Study (GWAS) in Critically Ill Sepsis Patients Identifies Single Nucleotide Polymorphisms (SNPs) Associated with AKI by Multiple Definitions: FR-PO094 by Miano, Todd A., Shashaty, Michael G., Reilly, John P., Jones, Tiffanie, Feng, Rui, Turner, Alexandra P., Dunn, Thomas, Ittner, Caroline, Anderson, Brian J., Christie, Jason, Giannini, Heather, Susztak, Katalin, Meyer, Nuala J.

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Prospective Study of Immune Phenotype and Associated Outcomes in Patients with Leukemia and Acute Respiratory Distress Syndrome by Ronner, Lukas, Giannini, Heather M., Miano, Todd A., Ittner, Caroline A.G., Turner, Alexandra P., Dunn, Thomas G., Agyekum, Roseline S., Dasgupta, Anushka, West, Kirsten, Jones, Tiffanie K., Shashaty, Michael G.S., Reilly, John P., Meyer, Nuala J.

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Sirolimus Enhances the Magnitude and Quality of Viral‐Specific CD8+ T‐Cell Responses to Vaccinia Virus Vaccination in Rhesus Macaques by Turner, A. P., Shaffer, V. O., Araki, K., Martens, C., Turner, P. L., Gangappa, S., Ford, M. L., Ahmed, R., Kirk, A. D., Larsen, C. P.

“…Sirolimus is a potent antiproliferative agent used clinically to prevent renal allograft rejection. However, little is known about the effects of maintenance…”
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