Search Results - "Turnbull, Daniel H"

Mouse MRI shows brain areas relatively larger in males emerge before those larger in females by Qiu, Lily R., Fernandes, Darren J., Szulc-Lerch, Kamila U., Dazai, Jun, Nieman, Brian J., Turnbull, Daniel H., Foster, Jane A., Palmert, Mark R., Lerch, Jason P.

“…Sex differences exist in behaviors, disease and neuropsychiatric disorders. Sexual dimorphisms however, have yet to be studied across the whole brain and…”
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Towards reliable reconstruction of the mouse brain corticothalamic connectivity using diffusion MRI by Arefin, Tanzil Mahmud, Lee, Choong Heon, Liang, Zifei, Rallapalli, Harikrishna, Wadghiri, Youssef Z., Turnbull, Daniel H., Zhang, Jiangyang

“…•A diffusion MRI mouse brain atlas compatible with the allen mouse brain atlas.•Node-to-node mouse thalamocortical structural connectivity using…”
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Cell specificity of Manganese-enhanced MRI signal in the cerebellum by Rallapalli, Harikrishna, Bayin, N. Sumru, Goldman, Hannah, Maric, Dragan, Nieman, Brian J., Koretsky, Alan P., Joyner, Alexandra L., Turnbull, Daniel H.

“…•The Purkinje cell layer is the source of high signal in Manganese-enhanced MRI (MEMRI) of the cerebellum.•Purkinje cells, not Bergmann glia, are responsible…”
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CSF1R inhibition depletes tumor-associated macrophages and attenuates tumor progression in a mouse sonic Hedgehog-Medulloblastoma model by Tan, I-Li, Arifa, Raquel Duque Nascimento, Rallapalli, Harikrishna, Kana, Veronika, Lao, Zhimin, Sanghrajka, Reeti Mayur, Sumru Bayin, N., Tanne, Antoine, Wojcinski, Alexandre, Korshunov, Andrey, Bhardwaj, Nina, Merad, Miriam, Turnbull, Daniel H., Lafaille, Juan J., Joyner, Alexandra L.

“…The immune microenvironment of tumors can play a critical role in promoting or inhibiting tumor progression depending on the context. We present evidence that…”
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Longitudinal MEMRI analysis of brain phenotypes in a mouse model of Niemann-Pick Type C disease by Rallapalli, Harikrishna, Darwin, Benjamin C., Toro-Montoya, Estefania, Lerch, Jason P., Turnbull, Daniel H.

“…Niemann-Pick Type C (NPC) is a rare genetic disorder characterized by progressive cell death in various tissues, particularly in the cerebellar Purkinje cells,…”
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Genetic Effects on Cerebellar Structure Across Mouse Models of Autism Using a Magnetic Resonance Imaging Atlas by Steadman, Patrick E., Ellegood, Jacob, Szulc, Kamila U., Turnbull, Daniel H., Joyner, Alexandra L., Henkelman, R. Mark, Lerch, Jason P.

“…Magnetic resonance imaging (MRI) of autism populations is confounded by the inherent heterogeneity in the individuals' genetics and environment, two factors…”
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Cerebellar folding is initiated by mechanical constraints on a fluid-like layer without a cellular pre-pattern by Lawton, Andrew K, Engstrom, Tyler, Rohrbach, Daniel, Omura, Masaaki, Turnbull, Daniel H, Mamou, Jonathan, Zhang, Teng, Schwarz, J M, Joyner, Alexandra L

“…Models based in differential expansion of elastic material, axonal constraints, directed growth, or multi-phasic combinations have been proposed to explain…”
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4D MEMRI atlas of neonatal FVB/N mouse brain development by Szulc, Kamila U., Lerch, Jason P., Nieman, Brian J., Bartelle, Benjamin B., Friedel, Miriam, Suero-Abreu, Giselle A., Watson, Charles, Joyner, Alexandra L., Turnbull, Daniel H.

“…The widespread use of the mouse as a model system to study brain development has created the need for noninvasive neuroimaging methods that can be applied to…”
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High-Throughput, High-Frequency 3-D Ultrasound for in Utero Analysis of Embryonic Mouse Brain Development by Aristizábal, Orlando, Mamou, Jonathan, Ketterling, Jeffrey A, Turnbull, Daniel H

“…Abstract With the emergence of the mouse as the predominant model system for studying mammalian brain development, in utero imaging methods are urgently…”
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The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum by Cheng, Yulan, Sudarov, Anamaria, Szulc, Kamila U, Sgaier, Sema K, Stephen, Daniel, Turnbull, Daniel H, Joyner, Alexandra L

“…Little is known about the genetic pathways and cellular processes responsible for regional differences in cerebellum foliation, which interestingly are…”
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MRI in mouse developmental biology by Turnbull, Daniel H., Mori, Susumu

“…Mice are used in many studies to determine the role of genetic and molecular factors in mammalian development and human congenital diseases. MRI has emerged as…”
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Cellular MRI contrast via coexpression of transferrin receptor and ferritin by Deans, Abby E., Wadghiri, Youssef Zaim, Bernas, Lisa M., Yu, Xin, Rutt, Brian K., Turnbull, Daniel H.

“…Recently there has been growing interest in the development and use of iron‐based contrast agents for cellular imaging with MRI. In this study we investigated…”
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Large-scale reorganization of the tonotopic map in mouse auditory midbrain revealed by MRI by Yu, Xin, Sanes, Dan H, Aristizabal, Orlando, Wadghiri, Youssef Zaim, Turnbull, Daniel H

“…The cortex is thought to be the primary site of sensory plasticity, particularly during development. Here, we report that large-scale reorganization of the…”
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Detection of Alzheimer's amyloid in transgenic mice using magnetic resonance microimaging by Wadghiri, Youssef Zaim, Sigurdsson, Einar M., Sadowski, Marcin, Elliott, James I., Li, Yongsheng, Scholtzova, Henrieta, Tang, Cheuk Ying, Aguinaldo, Gilbert, Pappolla, Miguel, Duff, Karen, Wisniewski, Thomas, Turnbull, Daniel H.

“…The presence of amyloid‐β (Aβ) plaques in the brain is a hallmark pathological feature of Alzheimer's disease (AD). Transgenic mice overexpressing mutant…”
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Novel Genetic Approach for In Vivo Vascular Imaging in Mice by Bartelle, Benjamin B, Berríos-Otero, César A, Rodriguez, Joe J, Friedland, Anne E, Aristizábal, Orlando, Turnbull, Daniel H

“…RATIONALE:The formation and maintenance of a functional vasculature is essential for normal embryonic development, and genetic changes that affect the…”
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MRI analysis of cerebellar and vestibular developmental phenotypes in Gbx2 conditional knockout mice by Szulc, Kamila U., Nieman, Brian J., Houston, Edward J., Bartelle, Benjamin B., Lerch, Jason P., Joyner, Alexandra L., Turnbull, Daniel H.

“…Purpose Our aim in this study was to apply three‐dimensional MRI methods to analyze early postnatal morphological phenotypes in a Gbx2 conditional knockout…”
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A Mathematical Model of Granule Cell Generation During Mouse Cerebellum Development by Leffler, Shoshana R., Legué, Emilie, Aristizábal, Orlando, Joyner, Alexandra L., Peskin, Charles S., Turnbull, Daniel H.

“…Determining the cellular basis of brain growth is an important problem in developmental neurobiology. In the mammalian brain, the cerebellum is particularly…”
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In Vivo Mn-Enhanced MRI for Early Tumor Detection and Growth Rate Analysis in a Mouse Medulloblastoma Model by Suero-Abreu, Giselle A, Praveen Raju, G, Aristizábal, Orlando, Volkova, Eugenia, Wojcinski, Alexandre, Houston, Edward J, Pham, Diane, Szulc, Kamila U, Colon, Daniel, Joyner, Alexandra L, Turnbull, Daniel H

“…Abstract Mouse models have increased our understanding of the pathogenesis of medulloblastoma (MB), the most common malignant pediatric brain tumor that often…”
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A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice by Sigurdsson, Einar M, Wadghiri, Youssef Z, Mosconi, Lisa, Blind, Jeffrey A, Knudsen, Elin, Asuni, Ayodeji, Scholtzova, Henrieta, Tsui, Wai H, Li, Yongsheng, Sadowski, Martin, Turnbull, Daniel H, de Leon, Mony J, Wisniewski, Thomas

“…Abstract Amyloid plaques are a characteristic feature in Alzheimer's disease (AD). A novel non-toxic contrast agent is presented, Gd-DTPA-K6Aβ1–30, which is…”
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Mn enhancement and respiratory gating for in utero MRI of the embryonic mouse central nervous system by Deans, Abby E., Wadghiri, Youssef Zaim, Berrios-Otero, César A., Turnbull, Daniel H.

“…The mouse is the preferred model organism for genetic studies of mammalian brain development. MRI has potential for in utero studies of mouse brain…”
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