Search Results - "Turluck, Daniel"
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A novel predictive pharmacokinetic/pharmacodynamic model of repolarization prolongation derived from the effects of terfenadine, cisapride and E-4031 in the conscious chronic av node—ablated, His bundle-paced dog
Published in Journal of pharmacological and toxicological methods (01-01-2006)“…Introduction: Terfenadine, cisapride, and E-4031, three drugs that prolong ventricular repolarization, were selected to evaluate the sensitivity of the…”
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Brain microdialysis and PK/PD correlation of pregabalin in rats
Published in European journal of drug metabolism and pharmacokinetics (01-01-2001)“…Pregabalin [PGB, (S)-3-isobutyl GABA, CI-1008] is a derivative of the inhibitory neurotransmitter g-aminobutyric acid (GABA). It has shown anticonvulsant,…”
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Inhibitors of Acyl-CoA:Cholesterol O-Acyltransferase. Synthesis and Pharmacological Activity of (±)-2-Dodecyl-α-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5-acetamide and Structurally Related Tetrazole Amide Derivatives
Published in Journal of medicinal chemistry (07-06-1996)“…A series of tetrazole amide derivatives of (±)-2-dodecyl-α-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5-acetamide (1) was prepared and evaluated for their…”
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α-Substituted Malonester Amides: Tools To Define the Relationship between ACAT Inhibition and Adrenal Toxicity
Published in Journal of medicinal chemistry (26-02-1998)“…We prepared a series of α-substituted malonester amides that were evaluated for their ability to inhibit acyl-CoA:cholesterol O-acyl transferase activity in…”
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Inhibitors of Acyl-CoA:Cholesterol O -Acyltransferase. Synthesis and Pharmacological Activity of (±)-2-Dodecyl-α-phenyl- N -(2,4,6-trimethoxyphenyl)-2 H -tetrazole-5-acetamide and Structurally Related Tetrazole Amide Derivatives
Published in Journal of medicinal chemistry (01-01-1996)Get full text
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