Search Results - "Turk, E."
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1
Nature‐Inspired Design and Application of Lipidic Lyotropic Liquid Crystals
Published in Advanced materials (Weinheim) (01-08-2019)“…Amphiphilic lipids aggregate in aqueous solution into a variety of structural arrangements. Among the plethora of ordered structures that have been reported,…”
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Homing in: Mechanisms of Substrate Targeting by Protein Kinases
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01-05-2018)“…Protein phosphorylation is the most common reversible post-translational modification in eukaryotes. Humans have over 500 protein kinases, of which more than a…”
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3
Miniature chiral beamsplitter based on gyroid photonic crystals
Published in Nature photonics (01-10-2013)“…The linearly polarizing beamsplitter 1 , 2 is a widely used optical component in photonics. It is typically built from a linearly birefringent crystal such as…”
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4
Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales
Published in Advanced materials (Weinheim) (01-03-2023)“…Surface curvature both emerges from, and influences the behavior of, living objects at length scales ranging from cell membranes to single cells to tissues and…”
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Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates
Published in Molecular cell (16-07-2015)“…Many tumors become addicted to autophagy for survival, suggesting inhibition of autophagy as a potential broadly applicable cancer therapy. ULK1/Atg1 is the…”
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6
Minimal surface scaffold designs for tissue engineering
Published in Biomaterials (01-10-2011)“…Abstract Triply-periodic minimal surfaces are shown to be a more versatile source of biomorphic scaffold designs than currently reported in the tissue…”
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7
Automatic brain tissue segmentation in fetal MRI using convolutional neural networks
Published in Magnetic resonance imaging (01-12-2019)“…MR images of fetuses allow clinicians to detect brain abnormalities in an early stage of development. The cornerstone of volumetric and morphologic analysis in…”
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Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase
Published in Molecular cell (06-02-2014)“…Bulk degradation of cytoplasmic material is mediated by a highly conserved intracellular trafficking pathway termed autophagy. This pathway is characterized by…”
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9
Coexistence of both gyroid chiralities in individual butterfly wing scales of Callophrys rubi
Published in Proceedings of the National Academy of Sciences - PNAS (20-10-2015)“…The wing scales of the Green Hairstreak butterfly Callophrys rubi consist of crystalline domains with sizes of a few micrometers, which exhibit a congenitally…”
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10
Minkowski tensors of anisotropic spatial structure
Published in New journal of physics (12-08-2013)“…This paper describes the theoretical foundation of and explicit algorithms for a novel approach to morphology and anisotropy analysis of complex spatial…”
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11
Universal hidden order in amorphous cellular geometries
Published in Nature communications (18-02-2019)“…Partitioning space into cells with certain extreme geometrical properties is a central problem in many fields of science and technology. Here we investigate…”
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12
AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
Published in Molecular cell (25-04-2008)“…AMPK is a highly conserved sensor of cellular energy status that is activated under conditions of low intracellular ATP. AMPK responds to energy stress by…”
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The Arabidopsis ABA-activated kinase OST1 phosphorylates the bZIP transcription factor ABF3 and creates a 14-3-3 binding site involved in its turnover
Published in PloS one (10-11-2010)“…Genetic evidence in Arabidopsis thaliana indicates that members of the Snf1-Related Kinases 2 family (SnRK2) are essential in mediating various stress-adaptive…”
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14
Splitting of the Universality Class of Anomalous Transport in Crowded Media
Published in Physical review letters (12-02-2016)“…We investigate the emergence of subdiffusive transport by obstruction in continuum models for molecular crowding. While the underlying percolation transition…”
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15
An optogenetic-phosphoproteomic study reveals dynamic Akt1 signaling profiles in endothelial cells
Published in Nature communications (26-06-2023)“…The serine/threonine kinase AKT is a central node in cell signaling. While aberrant AKT activation underlies the development of a variety of human diseases,…”
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Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling
Published in Cell (24-09-2015)“…Cancer cells acquire pathological phenotypes through accumulation of mutations that perturb signaling networks. However, global analysis of these events is…”
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The Toxoplasma Pseudokinase ROP5 Forms Complexes with ROP18 and ROP17 Kinases that Synergize to Control Acute Virulence in Mice
Published in Cell host & microbe (14-05-2014)“…Polymorphic rhoptry-secreted kinases (ROPs) are essential virulence factors of Toxoplasma gondii. In particular, the pseudokinase ROP5 is the major determinant…”
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Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases
Published in Molecular cell (05-05-2016)“…Cofilin/actin-depolymerizing factor (ADF) proteins are critical nodes that relay signals from protein kinase cascades to the actin cytoskeleton, in particular…”
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19
Local origin of global contact numbers in frictional ellipsoid packings
Published in Physical review letters (17-04-2015)“…In particulate soft matter systems the average number of contacts Z of a particle is an important predictor of the mechanical properties of the system. Using…”
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An AMPK-Independent Signaling Pathway Downstream of the LKB1 Tumor Suppressor Controls Snail1 and Metastatic Potential
Published in Molecular cell (07-08-2014)“…The serine/threonine kinase LKB1 is a tumor suppressor whose loss is associated with increased metastatic potential. In an effort to define biochemical…”
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