Search Results - "Turk, Amy N."

Combinatorial Therapy With Tamoxifen and Trifluoperazine Effectively Inhibits Malignant Peripheral Nerve Sheath Tumor Growth by Targeting Complementary Signaling Cascades by Brosius, Stephanie N, Turk, Amy N, Byer, Stephanie J, Longo, Jody Fromm, Kappes, John C, Roth, Kevin A, Carroll, Steven L

“…ABSTRACTChemotherapeutic agents effective against malignant peripheral nerve sheath tumors (MPNSTs) are urgently needed. We recently found that tamoxifen…”
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Transgenic Mice Overexpressing Neuregulin-1 Model Neurofibroma-Malignant Peripheral Nerve Sheath Tumor Progression and Implicate Specific Chromosomal Copy Number Variations in Tumorigenesis by Kazmi, Syed J, Byer, Stephanie J, Eckert, Jenell M, Turk, Amy N, Huijbregts, Richard P.H, Brossier, Nicole M, Grizzle, William E, Mikhail, Fady M, Roth, Kevin A, Carroll, Steven L

“…Patients with neurofibromatosis type 1 (NF1) develop benign plexiform neurofibromas that frequently progress to become malignant peripheral nerve sheath tumors…”
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Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis by Brosius, Stephanie N., Turk, Amy N., Byer, Stephanie J., Brossier, Nicole M., Kohli, Latika, Whitmire, Amber, Mikhail, Fady M., Roth, Kevin A., Carroll, Steven L.

“…Malignant peripheral nerve sheath tumors (MPNSTs) are Schwann cell-derived malignancies that arise from plexiform neurofibromas in patients with mutation of…”
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Tamoxifen inhibits malignant peripheral nerve sheath tumor growth in an estrogen receptor-independent manner by Byer, Stephanie J., Eckert, Jenell M., Brossier, Nicole M., Clodfelder-Miller, Buffie J., Turk, Amy N., Carroll, Andrew J., Kappes, John C., Zinn, Kurt R., Prasain, Jeevan K., Carroll, Steven L.

“…Few therapeutic options are available for malignant peripheral nerve sheath tumors (MPNSTs), the most common malignancy associated with neurofibromatosis type…”
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Tamoxifen enhances therapeutic effects of gemcitabine on cholangiocarcinoma tumorigenesis by Jing, Gu, Yuan, Kaiyu, Turk, Amy N, Jhala, Nirag C, Arnoletti, Juan P, Zhang, Kui, McDonald, Jay M, Chen, Yabing

“…Cholangiocarcinoma is a highly malignant tumor with limited therapeutic options. We have previously reported that tamoxifen (TMX) induces apoptosis of…”
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Orthotopic xenografting of human luciferase-tagged malignant peripheral nerve sheath tumor cells for in vivo testing of candidate therapeutic agents by Turk, Amy N, Byer, Stephanie J, Zinn, Kurt R, Carroll, Steven L

“…Although in vitro screens are essential for the initial identification of candidate therapeutic agents, a rigorous assessment of the drug's ability to inhibit…”
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Abstract 4089: Calmodulin antagonists inhibit cholangiocarcinoma tumorigenesis independent of gemcitabine by the activating of caspase 2 by Jing, Gu, Yuan, Kaiyu, Turk, Amy N., McDonald, Jay M., Chen, Yabing

“…Cholangiocarcinoma is a highly malignant tumor with limited therapeutic options. Gemcitabine (GMT) is currently used as a first line chemotherapeutical reagent…”
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Abstract 126: Gemcitabine enhances therapeutic effect of tamoxifen on cholangiocarcinoma by Jing, Gu, Turk, Amy N., Sun, Yong, Pawar, Pritish, Chen, Yabing, McDonald, Jay M.

“…Gemcitabine enhances therapeutic effect of tamoxifen on cholangiocarcinoma Gu Jing, Amy N Turk, Yong Sun, Pritish Pawar, Yabing Chen, Jay M McDonald…”
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Orthotopic Xenografting of Human Luciferase-Tagged Malignant Peripheral Nerve Sheath Tumor Cells for in vivo Testing of Candidate Therapeutic Agents by Turk, Amy N., Byer, Stephanie J., Zinn, Kurt R., Carroll, Steven L.

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