Search Results - "Turicek, David"

CAR T-cell detection scoping review: an essential biomarker in critical need of standardization by Turicek, David P, Giordani, Victoria M, Moraly, Josquin, Taylor, Naomi, Shah, Nirali N

“…The expansion and persistence of chimeric antigen receptor (CAR) T-cells in patients are associated with response, toxicity, and long-term efficacy. As such,…”
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The epigenetic trajectory of type 1 regulatory T cells by Turicek, David P, Wan, Xiaoxiao

“…The epigenome of T follicular helper cells prepares them for conversion into type 1 regulatory T cells…”
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CXCR4 allows T cell acute lymphoblastic leukemia to escape from JAK1/2 and BCL2 inhibition through CNS infiltration by Walker, Kirsti L., Rinella, Sean P., Hess, Nicholas J., Turicek, David P., Kabakov, Sabrina A., Zhu, Fen, Bouchlaka, Myriam N., Olson, Sydney L., Cho, Monica M., Quamine, Aicha E., Feils, Arika S., Gavcovich, Tara B., Rui, Lixin, Capitini, Christian M.

“…Targeting the JAK/STAT and BCL2 pathways in patients with relapsed/refractory T cell acute lymphoblastic leukemia (T-ALL) may provide an alternative approach…”
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Inflammatory CD4/CD8 double-positive human T cells arise from reactive CD8 T cells and are sufficient to mediate GVHD pathology by Hess, Nicholas J, Turicek, David P, Riendeau, Jeremiah, McIlwain, Sean J, Contreras Guzman, Emmanuel, Nadiminti, Kalyan, Hudson, Amy, Callander, Natalie S, Skala, Melissa C, Gumperz, Jenny E, Hematti, Peiman, Capitini, Christian M

“…An important paradigm in allogeneic hematopoietic cell transplantations (allo-HCTs) is the prevention of graft-versus-host disease (GVHD) while preserving the…”
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1471 The role of cholesterol handling in gamma delta T cell cytotoxicity against highly immune suppressive pancreas ductal adenocarcinoma by Ebben, Johnathan, Turicek, David, Hossan, Md Shahadat, Stram, Austin, Lin, Ethan, Hess, Nicholas J, Mayhew, Zachary, Kinney, Melissa, Capitini, Christian, Kratz, Jeremy

“…BackgroundPancreas ductal adenocarcinoma (PDAC) is highly resistant to most therapies, including immunotherapy. PDAC create highly immunosuppressive tumor…”
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Differentiation of a CD4/CD8αβ Double Positive T Cell Population from the CD8 Pool Is Both Predictive and Sufficient to Mediate Graft-Vs-Host Disease by Hess, Nicholas J., Turicek, David, Hudson, Amy, Hematti, Peiman, Gumperz, Jenny, Capitini, Christian M.

“…Acute graft-vs-host disease (aGVHD) and cancer relapse remain the primary complications following an allogeneic hematopoietic stem cell transplantation…”
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Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-Like Syndrome by Hines, Melissa R., Knight, Tristan E., McNerney, Kevin O., Leick, Mark B., Jain, Tania, Ahmed, Sairah, Frigault, Matthew J., Hill, Joshua A., Jain, Michael D., Johnson, William T., Lin, Yi, Mahadeo, Kris M., Maron, Gabriela M., Marsh, Rebecca A., Neelapu, Sattva S., Nikiforow, Sarah, Ombrello, Amanda K., Shah, Nirav N., Talleur, Aimee C., Turicek, David, Vatsayan, Anant, Wong, Sandy W., Maus, Marcela V., Komanduri, Krishna V., Berliner, Nancy, Henter, Jan-Inge, Perales, Miguel-Angel, Frey, Noelle V., Teachey, David T., Frank, Matthew J., Shah, Nirali N.

“…•Hemophagocytic lymphohistiocytosis (HLH)-like toxicities occur after CAR T-cells•This is now termed immune effector cell (IEC) associated HLH-like syndrome…”
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