Search Results - "Turhanen, Petri A"
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Synthesis of the biologically important dideuterium-labelled adenosine triphosphate analogue ApppI( d 2 )
Published in Beilstein journal of organic chemistry (14-10-2022)“…The chemical synthesis of the dideuterium-labelled ATP analogue 1-adenosin-5’-yl-3-(3-methylbut-3-en-1,1- d 2 -1-ol) triphosphoric acid diester (ApppI( d 2 ))…”
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Advanced material and approach for metal ions removal from aqueous solutions
Published in Scientific reports (11-03-2015)“…A Novel approach to remove metals from aqueous solutions has been developed. The method is based on a resin free, solid, non-toxic, microcrystalline…”
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6-Bromo-1-hydroxyhexane-1,1-bisphosphonic Acid Monosodium Salt
Published in MolBank (01-10-2022)“…The synthesis of 6-bromo-1-hydroxyhexane-1,1-bisphosphonic acid monosodium salt has been described in detail and characterized by 1H, 13C, 31P NMR spectroscopy…”
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Editorial: Phosphonate chemistry in drug design and development, Volume II
Published in Frontiers in chemistry (23-11-2022)Get full text
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Editorial: Phosphonate Chemistry in Drug Design and Development
Published in Frontiers in chemistry (30-04-2021)Get full text
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3-(3-Bromophenyl)-7-acetoxycoumarin
Published in MolBank (01-12-2022)“…In natural product synthesis, the procurement of easily accessible starting materials is crucial. Chromenones and their subclass, coumarins, are a wide family…”
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Synthesis of a Biologically Important Adenosine Triphosphate Analogue, ApppD
Published in ACS omega (30-06-2017)“…The chemical synthesis of a adenosine triphosphate analogue, 1-adenosin-5′-yl 3-(3-methylbut-2-enyl) triphosphoric acid diester (ApppD), is described. ApppD is…”
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Correction to “Synthesis of a Biologically Important Adenosine Triphosphate Analogue, ApppD”
Published in ACS omega (31-08-2017)“…[This corrects the article DOI: 10.1021/acsomega.7b00531.]…”
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(E)‑Di-iodination of Alkynes Using Dried Dowex H+/NaI Approach
Published in ACS omega (10-09-2019)“…We investigated the usefulness of the dried Dowex H+/NaI approach for the selective di-iodination of alkynes. The Dowex H+/NaI approach selectively produces…”
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Green and Efficient Esterification Method Using Dried Dowex H+/NaI Approach
Published in ACS omega (31-05-2019)“…The usefulness of dried Dowex H+ cation-exchange resin with or without sodium iodide (NaI) as a catalyst system for different kinds of esterifications using…”
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Two strategies for the synthesis of the biologically important ATP analogue ApppI, at a multi-milligram scale
Published in Beilstein journal of organic chemistry (13-11-2015)“…Two strategies for the synthesis of the ATP (adenosine triphosphate) analogue ApppI [1-adenosin-5'-yl 3-(3-methylbut-3-enyl)triphosphoric acid diester] (1) are…”
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Synthesis of medronic acid monoesters and their purification by high-performance countercurrent chromatography or by hydroxyapatite
Published in Beilstein journal of organic chemistry (07-10-2016)“…We achieved the synthesis of important medronic acid monoalkyl esters via the dealkylation of mixed trimethyl monoalkyl esters of medronic acid. Two methods…”
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Simple and User-Friendly Methodology for Crystal Water Determination by Quantitative Proton NMR Spectroscopy in Deuterium Oxide
Published in Analytical chemistry (Washington) (21-11-2023)“…In drug research and development, knowledge of the precise structure of an active ingredient is crucial. However, it is equally important to know the water…”
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Semi-preparative high-performance countercurrent chromatography method for the purification of chemically synthesized ATP analogue, ApppI
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-09-2017)“…[Display omitted] An efficient high-performance countercurrent chromatography (HPCCC) based method has been developed for the purification of chemically…”
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Preparation of mixed trialkyl alkylcarbonate derivatives of etidronic acid via an unusual route
Published in Beilstein journal of organic chemistry (20-11-2012)“…A method to prepare four (3a-d) trialkyl alkylcarbonate esters of etidronate from P,P'-dimethyl etidronate and alkyl chloroformate was developed by utilizing…”
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Real-Time On-Site Multielement Analysis of Environmental Waters with a Portable X‑ray Fluorescence (pXRF) System
Published in Analytical chemistry (Washington) (30-08-2022)“…Strict regulations are in place to control the effluents of mining sites and other industries. Heavy metal contamination of aquatic systems caused by leakages…”
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Synthesis of Triple-Bond-Containing 1‑Hydroxy-1,1-bisphosphonic Acid Derivatives To Be Used as Precursors in “Click” Chemistry: Two Examples
Published in Journal of organic chemistry (03-07-2014)“…The synthesis of novel (ω-alkynyl-1-hydroxy-1,1-diyl)bisphosphonic acid tetramethyl esters (1a–c), their P,P′-dimethyl esters (2a–c), and two trimethyl ester…”
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A Novel Strategy for the Preparation of Naturally Occurring Phosphocitrate and Its Partially Esterified Derivatives
Published in Journal of organic chemistry (16-02-2007)“…A novel method for the synthesis of phosphocitrate (1, PC) starting from triethyl ester of citric acid and MeOPCl2 is described. The method is based on…”
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Structural Diversity in Antiosteolytic Bisphosphonates: Deciphering Structure–Activity Trends in Ultra Long Controlled Release Phenomena
Published in ACS applied bio materials (18-12-2023)“…Bisphosphonate (BP)-based treatments have been extensively prescribed for bone-related conditions, particularly for osteoporosis. Their low bioavailability…”
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Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions
Published in Beilstein journal of organic chemistry (21-01-2008)“…Unexpected degradation of the P-C-P bridge from novel bisphosphonate derivative 1a and known etidronate trimethyl ester (1b) has been observed under mild…”
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