Search Results - "Turecki, G."

Neuropathology of suicide: recent findings and future directions by Lutz, P-E, Mechawar, N, Turecki, G

“…Suicide is a major public health concern and a leading cause of death in most societies. Suicidal behaviour is complex and heterogeneous, likely resulting from…”
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Astrocytic abnormalities and global DNA methylation patterns in depression and suicide by Nagy, C, Suderman, M, Yang, J, Szyf, M, Mechawar, N, Ernst, C, Turecki, G

“…Astrocytes are glial cells specific to the central nervous system and involved in numerous brain functions, including regulation of synaptic transmission and…”
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DNA methylation and childhood maltreatment: From animal models to human studies by Lutz, P.-E, Turecki, G

“…Highlights • Childhood maltreatment is among the strongest predictors of psychiatric pathology. • DNA methylation mediates life-long neurobiological effects of…”
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Glial fibrillary acidic protein is differentially expressed across cortical and subcortical regions in healthy brains and downregulated in the thalamus and caudate nucleus of depressed suicides by Torres-Platas, S G, Nagy, C, Wakid, M, Turecki, G, Mechawar, N

“…There is mounting evidence to suggest aberrant astrocytic function in depression and suicide. Independent studies have reported astrocytic abnormalities in…”
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BECon: a tool for interpreting DNA methylation findings from blood in the context of brain by Edgar, R D, Jones, M J, Meaney, M J, Turecki, G, Kobor, M S

“…Tissue differences are one of the largest contributors to variability in the human DNA methylome. Despite the tissue-specific nature of DNA methylation, the…”
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A role for activity‐dependent epigenetics in the development and treatment of major depressive disorder by Nagy, C., Vaillancourt, K., Turecki, G.

“…Chronic stressors, during developmental sensitive periods and beyond, contribute to the risk of developing psychiatric conditions, including major depressive…”
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Personality traits as correlates of suicidal ideation, suicide attempts, and suicide completions: a systematic review by Brezo, J., Paris, J., Turecki, G.

“…Objective:  Involvement of personality traits in susceptibility to suicidality has been the subject of research since the 1950s. Because of the diversity of…”
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S.08.02 miRNA predictors and correlates of antidepressant response by Turecki, G

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Cognitive inhibition in depression and suicidal behavior: a neuroimaging study by Richard-Devantoy, S, Ding, Y, Lepage, M, Turecki, G, Jollant, F

“…Cognitive inhibition deficits have previously been found in suicide attempters. This study examined the neural basis for these deficits in depressed patients…”
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Epigenetic Changes in the Suicidal Brain by Turecki, G

“…Suicide and related behaviors are complex phenomena associated with different risk factors. While most individuals who display suicidal behavior do not have a…”
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Associations among oxytocin receptor gene (OXTR) DNA methylation in adulthood, exposure to early life adversity, and childhood trajectories of anxiousness by Gouin, J. P., Zhou, Q. Q., Booij, L., Boivin, M., Côté, S. M., Hébert, M., Ouellet-Morin, I., Szyf, M., Tremblay, R. E., Turecki, G., Vitaro, F.

“…Recent models propose deoxyribonucleic acid methylation of key neuro-regulatory genes as a molecular mechanism underlying the increased risk of mental disorder…”
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Child abuse associates with an imbalance of oligodendrocyte-lineage cells in ventromedial prefrontal white matter by Tanti, A, Kim, J J, Wakid, M, Davoli, M-A, Turecki, G, Mechawar, N

“…Child abuse (CA) is a major risk factor for depression, and strongly associates with suicidal behavior during adulthood. Neuroimaging studies have reported…”
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Epigenetic regulation of BDNF expression according to antidepressant response by Lopez, J P, Mamdani, F, Labonte, B, Beaulieu, M-M, Yang, J P, Berlim, M T, Ernst, C, Turecki, G

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Polyamines and suicide risk by Turecki, G

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Methylomic profiling of cortex samples from completed suicide cases implicates a role for PSORS1C3 in major depression and suicide by Murphy, T M, Crawford, B, Dempster, E L, Hannon, E, Burrage, J, Turecki, G, Kaminsky, Z, Mill, J

“…Major depressive disorder (MDD) represents a major social and economic health issue and constitutes a major risk factor for suicide. The molecular pathology of…”
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A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior by ANGUELOVA, M, BENKELFAT, C, TURECKI, G

“…The different serotonin (5-HT) receptors, including the serotonin transporter (5-HTT), are excellent candidate genes for suicide and suicidal behavior, and…”
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VGF function in depression and antidepressant efficacy by Jiang, C, Lin, W-J, Sadahiro, M, Labonté, B, Menard, C, Pfau, M L, Tamminga, C A, Turecki, G, Nestler, E J, Russo, S J, Salton, S R

“…Brain-derived neurotrophic factor (BDNF) is a critical effector of depression-like behaviors and antidepressant responses. Here, we show that VGF…”
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Impulsive-aggressive behaviours and completed suicide across the life cycle: a predisposition for younger age of suicide by McGirr, A, Renaud, J, Bureau, A, Seguin, M, Lesage, A, Turecki, G

“…It is unclear whether the association between impulsive-aggressive behaviours and suicide exists across different ages. Via psychological autopsy, we examined…”
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Altered brain processing of decision-making in healthy first-degree biological relatives of suicide completers by Ding, Y, Pereira, F, Hoehne, A, Beaulieu, M-M, Lepage, M, Turecki, G, Jollant, F

“…Suicidal behavior is heritable, with the transmission of risk being related to the transmission of vulnerability traits. Previous studies suggest that risky…”
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Deficit of cognitive inhibition in depressed elderly: A neurocognitive marker of suicidal risk by Richard-Devantoy, S, Jollant, F, Kefi, Z, Turecki, G, J.P.Olié, Annweiler, C, Beauchet, O, Le Gall, D

“…Abstract Background Cognitive deficits, in relation to ventral and dorsal prefrontal cortex dysfunctions, have been associated with a higher risk of suicidal…”
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