Search Results - "Turcsányi, Peter"

Neutrophils in chronic lymphocytic leukemia are permanently activated and have functional defects by Manukyan, Gayane, Papajik, Tomas, Gajdos, Petr, Mikulkova, Zuzana, Urbanova, Renata, Gabcova, Gabriela, Kudelka, Milos, Turcsányi, Peter, Ryznerova, Pavlina, Prochazka, Vit, Kriegova, Eva

“…A growing body of studies highlights involvement of neutrophils in cancer development and progression. Our aim was to assess the phenotypic and functional…”
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External validation of International Prognostic Score for asymptomatic early stage chronic lymphocytic leukaemia and proposal of an alternative score by Smolej, Lukáš, Turcsányi, Peter, Kubová, Zuzana, Zuchnická, Jana, Mihályová, Jana, Šimkovič, Martin, Vodárek, Pavel, Krčméryová, Mária, Móciková, Heidi, Brejcha, Martin, Špaček, Martin

“…Summary Most patients with chronic lymphocytic leukaemia (CLL) are nowadays diagnosed without any symptoms and do not require therapy. A prognostic score…”
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Assessment of two different methods of calculating a heating demand by Turcsányi, Peter, Sedláková, Anna

“…Phenomenon of today′s era is lowering overall energy performance and greenhouse gas emissions. European Union and its members came from an “uncontrollable”…”
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Numbers of CD8+PD-1+ and CD4+PD-1+ Cells in Peripheral Blood of Patients with Chronic Lymphocytic Leukemia Are Independent of Binet Stage and Are Significantly Higher Compared to Healthy Volunteers by Novák, Martin, Procházka, Vit, Turcsányi, Peter, Papajík, Tomáš

“…The programmed cell death pathway is involved in functional impairment of cytotoxic CD8+ T cells in chronic viral infection and in tumor immune evasion. The…”
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Resistance-Associated Mutations in Chronic Lymphocytic Leukemia Patients Treated With Novel Agents by Sedlarikova, Lenka, Petrackova, Anna, Papajik, Tomas, Turcsanyi, Peter, Kriegova, Eva

“…Inhibitors of B-cell receptor signaling, ibrutinib and idelalisib, and BCL-2 antagonist, venetoclax, have become the mainstay of treatment for chronic…”
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Idelalisib plus rituximab versus ibrutinib in the treatment of relapsed/refractory chronic lymphocytic leukaemia: A real‐world analysis from the Chronic Lymphocytic Leukemia Patients Registry (CLLEAR) by Špaček, Martin, Smolej, Lukáš, Šimkovič, Martin, Nekvindová, Lucie, Křístková, Zlatuše, Brychtová, Yvona, Panovská, Anna, Mašlejová, Stanislava, Bezděková, Lucie, Écsiová, Dominika, Vodárek, Pavel, Zuchnická, Jana, Mihályová, Jana, Urbanová, Renata, Turcsányi, Peter, Lysák, Daniel, Novák, Jan, Brejcha, Martin, Líkařová, Tereza, Vodička, Prokop, Baranová, Jana, Trněný, Marek, Doubek, Michael

“…Summary Idelalisib (idela), a phosphatidylinositol 3‐kinase inhibitor, and ibrutinib, a Bruton tyrosine kinase inhibitor, were the first oral targeted agents…”
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COVID-19 in patients with chronic lymphocytic leukemia: a multicenter analysis by the Czech CLL study group by Šimkovič, Martin, Turcsányi, Peter, Špaček, Martin, Mihályová, Jana, Ryznerová, Pavlína, Maco, Mária, Vodárek, Pavel, Écsiová, Dominika, Poul, Hynek, Móciková, Heidi, Zuchnická, Jana, Panovská, Anna, Lekaa, Mohammad, Oršulová, Martina, Prchlíková, Adéla, Stejskal, Lukáš, Mašlejová, Stanislava, Brychtová, Yvona, Bezděková, Lucie, Papajík, Tomáš, Lysák, Daniel, Trněný, Marek, Smolej, Lukáš, Doubek, Michael

“…Patients with chronic lymphocytic leukemia (CLL) have a high risk of poor outcomes related to coronavirus disease 2019 (COVID-19). This multicenter cohort…”
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Deciphering the complex circulating immune cell microenvironment in chronic lymphocytic leukaemia using patient similarity networks by Mikulkova, Zuzana, Manukyan, Gayane, Turcsanyi, Peter, Kudelka, Milos, Urbanova, Renata, Savara, Jakub, Ochodkova, Eliska, Brychtova, Yvona, Molinsky, Jan, Simkovic, Martin, Starostka, David, Novak, Jan, Janca, Ondrej, Dihel, Martin, Ryznerova, Pavlina, Mohammad, Lekaa, Papajik, Tomas, Kriegova, Eva

“…The tissue microenvironment in chronic lymphocytic leukaemia (CLL) plays a key role in the pathogenesis of CLL, but the complex blood microenvironment in CLL…”
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High CXCR3 on Leukemic Cells Distinguishes IgHVmut from IgHVunmut in Chronic Lymphocytic Leukemia: Evidence from CD5high and CD5low Clones by Kriegova, Eva, Turcsanyi, Peter, Savara, Jakub, Kraiczova, Veronika Smotkova, Urbanova, Renata, Mikulkova, Zuzana, Papajík, T., Manukyan, Gayane, Kudelka, Milos

“…Despite the shared pattern of surface antigens, neoplastic cells in chronic lymphocytic leukemia (CLL) are highly heterogeneous in CD5 expression, a marker…”
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2-[18F]fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography examination in patients with chronic lymphocytic leukemia may reveal Richter transformation by Papajík, Tomáš, Myslive ek, Miroslav, Urbanová, Renata, Buriánková, Eva, Kapitá ová, Zuzana, Procházka, Vít, Turcsányi, Peter, Formánek, Radim, Henzlová, Lenka, Flodr, Patrik, Jarošová, Marie, Indrák, Karel

“…Abstract The significance of positron emission tomography/computed tomography (PET/CT) in chronic lymphocytic leukemia (CLL) has not yet been systematically…”
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Spontaneous splenic rupture in a patient with acute promyelocytic leukaemia during induction chemotherapy by Kuba, Adam, Szotkowski, Tomas, Rohon, Peter, Faber, Edgar, Turcsanyi, Peter, Hubacek, Jaromir, Holzerova, Milena, Prasil, Vojtech, Jarosova, Marie, Indrak, Karel

“…Acute promyelocytic leukaemia (APL) is a subtype of acute myeloid leukaemia with high curability rates. However, it is often accompanied by severe coagulopathy…”
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Revisiting Richter transformation in the era of novel CLL agents by Petrackova, Anna, Turcsanyi, Peter, Papajik, Tomas, Kriegova, Eva

“…Richter transformation (RT) is the development of aggressive lymphoma – most frequently diffuse large B-cell lymphoma (DLBCL) and rarely Hodgkin lymphoma (HL)…”
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Rare germline ATM variants of uncertain significance in chronic lymphocytic leukaemia and other cancers by Petrackova, Anna, Savara, Jakub, Turcsanyi, Peter, Gajdos, Petr, Papajik, Tomas, Kriegova, Eva

“…Summary Germline pathogenic ATM (ataxia‐telangiectasia mutated) variants are associated with the risk of multiple cancers; however, genetic testing reveals a…”
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Second Line Treatment with Bruton Tyrosine Kinase Inhibitor (BTKi) or Bcl-2 Inhibitor (Bcl-2i) in Patients with Chronic Lymphocytic Leukemia (CLL): Primary Analysis of the Czech Study Group for CLL (CSCLL) by Mihalyova, Jana, Panovska, Anna, Simkovic, Martin, Turcsanyi, Peter, Spacek, Martin, Brejcha, Martin, Lysak, Daniel, Mocikova, Heidi, Pavlova, Sarka, Chrapava, Marika, Zuchnicka, Jana, Brychtova, Yvona, Vodarek, Pavel, Urbanova, Renata, Likarova, Tereza, Malcikova, Jitka, Jurkova, Tereza, Lancova, Klara, Bezdekova, Lucie, Papajik, Tomas, Baranova, Jana, Arpas, Tomas, Pospisilova, Sarka, Smolej, Lukas, Doubek, Michael

“…Introduction: Venetoclax in combination with rituximab (VenR) along with either ibrutinib or acalabrutinib monotherapy represent the most common regimens…”
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Improving risk-stratification of patients with chronic lymphocytic leukemia using multivariate patient similarity networks by Turcsanyi, Peter, Kriegova, Eva, Kudelka, Milos, Radvansky, Martin, Kruzova, Lenka, Urbanova, Renata, Schneiderova, Petra, Urbankova, Helena, Papajik, Tomas

“…•Patient similarity network (PSN) is a new approach for patient stratification.•PSN clusters patients based on their similarities in various features.•PSN…”
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Next-Generation Optical Mapping Reveals Numerous Previously Unrecognizable Structural Variants in Chronic Lymphocytic Leukemia by Fillerova, Regina, Petrackova, Anna, Papajik, Tomas, Turcsanyi, Peter, Behalek, Marek, Gajdos, Petr, Ryznerova, Pavlina, Kruzova, Lenka, Urbankova, Helena, Minarik, Jiri, Kriegova, Eva

“…Introduction: Chronic lymphocytic leukemia (CLL) is the most common form of leukemia in adults in western countries. Although a number of genetic aberrations…”
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Towards a Better Characterisation of Leukemic Cells in Chronic Lymphocytic Leukaemia: Cell-Size Heterogeneity Reflects Their Activation Status and Migratory Abilities by Manukyan, Gayane, Mikulkova, Zuzana, Turcsanyi, Peter, Savara, Jakub, Trajerová, Markéta, Kubova, Zuzana, Papajik, Tomas, Kriegova, Eva

“…Chronic lymphocytic leukaemia (CLL) is a genetically, morphologically and phenotypically heterogeneous chronic disease with clinical variability between…”
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Complex karyotype as a predictor of high-risk chronic lymphocytic leukemia: A single center experience over 12 years by Kruzova, Lenka, Schneiderova, Petra, Holzerova, Milena, Vatolikova, Michaela, Divoka, Martina, Turcsanyi, Peter, Urbanova, Renata, Kudelka, Milos, Radvansky, Martin, Kriegova, Eva, Papajik, Tomas, Urbankova, Helena

“…•Complex karyotype affects clinical and treatment decision-making in the diagnosis of chronic lymphocytic leukemia.•Complex karyotype is a marker of poor…”
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Dynamic changes in HLA-DR expression during short-term and long-term ibrutinib treatment in patients with chronic lymphocytic leukemia by Manukyan, Gayane, Turcsanyi, Peter, Mikulkova, Zuzana, Gabcova, Gabriela, Urbanova, Renata, Gajdos, Petr, Smotkova Kraiczova, Veronika, Zehnalova, Sarka, Papajik, Tomas, Kriegova, Eva

“…•Ibrutinib influences the expression of HLA-DR on CLL cells.•Ibrutinib gradually increases HLA-DR levels on circulating monocyte subsets.•Immunomodulatory…”
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High CXCR3 on Leukemic Cells Distinguishes IgHV mut from IgHV unmut in Chronic Lymphocytic Leukemia: Evidence from CD5 high and CD5 low Clones by Manukyan, Gayane, Papajik, Tomas, Mikulkova, Zuzana, Urbanova, Renata, Kraiczova, Veronika Smotkova, Savara, Jakub, Kudelka, Milos, Turcsanyi, Peter, Kriegova, Eva

“…Despite the shared pattern of surface antigens, neoplastic cells in chronic lymphocytic leukemia (CLL) are highly heterogeneous in CD5 expression, a marker…”
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