Search Results - "Turcotte, Émilie"

The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors by Watson, Mark, Roulston, Anne, Bélec, Laurent, Billot, Xavier, Marcellus, Richard, Bédard, Dominique, Bernier, Cynthia, Branchaud, Stéphane, Chan, Helen, Dairi, Kenza, Gilbert, Karine, Goulet, Daniel, Gratton, Michel-Olivier, Isakau, Henady, Jang, Anne, Khadir, Abdelkrim, Koch, Elizabeth, Lavoie, Manon, Lawless, Michael, Nguyen, Mai, Paquette, Denis, Turcotte, Émilie, Berger, Alvin, Mitchell, Matthew, Shore, Gordon C., Beauparlant, Pierre

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Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777 by Beauparlant, Pierre, Bédard, Dominique, Bernier, Cynthia, Chan, Helen, Gilbert, Karine, Goulet, Daniel, Gratton, Michel-Olivier, Lavoie, Manon, Roulston, Anne, Turcotte, Émilie, Watson, Mark

“…GMX1778 was recently shown to function as a potent inhibitor of nicotinamide phosphoribosyl transferase. To translate the discovery of GMX1778 mechanism of…”
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Abstract LB-33: Pre-clinical evaluation of AB-16B5, a monoclonal antibody specific for tumor-associated sCLU, demonstrates therapeutic potential as an inhibitor of EMT in prostate, pancreatic and lung cancer by Tremblay, Gilles B., Viau, Elisabeth, Malouin, Mireille, Turcotte, Émilie, Fortin, Annie, Filion, Mario

“…Abstract Secreted clusterin (sCLU) exhibits elevated expression in several cancer indications. sCLU plays a pro-survival role in tumors and, more recently, it…”
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