Search Results - "Turco, D. Del"
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Low-dose irradiation prior to bone marrow transplantation results in ATM activation and increased lethality in Atm-deficient mice
Published in Bone marrow transplantation (Basingstoke) (01-04-2016)“…Ataxia telangiectasia is a genetic instability syndrome characterized by neurodegeneration, immunodeficiency, severe bronchial complications, hypersensitivity…”
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Thalamic involvement in a spinocerebellar ataxia type 2 (SCA2) and a spinocerebellar ataxia type 3 (SCA3) patient, and its clinical relevance
Published in Brain (London, England : 1878) (01-10-2003)“…In spite of the considerable progress in clinical and molecular research, knowledge regarding brain damage in spinocerebellar ataxia type 2 (SCA2) and type 3…”
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Degeneration of the central vestibular system in spinocerebellar ataxia type 3 (SCA3) patients and its possible clinical significance
Published in Neuropathology and applied neurobiology (01-08-2004)“…Although the vestibular complex represents an important component of the neural circuits crucial for the maintenance of truncal and postural stability, and it…”
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Extended pathoanatomical studies point to a consistent affection of the thalamus in spinocerebellar ataxia type 2
Published in Neuropathology and applied neurobiology (01-04-2005)“…The involvement of the thalamus during the course of the currently known polyglutamine diseases is still a matter of debate. While it is well‐known that this…”
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The intralaminar nuclei assigned to the medial pain system and other components of this system are early and progressively affected by the Alzheimer's disease-related cytoskeletal pathology
Published in Journal of chemical neuroanatomy (01-05-2002)“…The intralaminar nuclei of the human thalamus are integrated into the ascending reticular activating system and into limbic, oculomotor and somatomotor loops…”
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Pathoanatomy of Cerebellar Degeneration in Spinocerebellar Ataxia Type 2 (SCA2) and Type 3 (SCA3)
Published in Cerebellum (London, England) (01-09-2012)“…The cerebellum is one of the well-known targets of the pathological processes underlying spinocerebellar ataxia type 2 (SCA2) and type 3 (SCA3). Despite its…”
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Bone marrow transplantation improves the outcome of Atm-deficient mice through the migration of ATM-competent cells
Published in Human molecular genetics (01-02-2013)“…Ataxia telangiectasia (A-T) is a highly pleiotropic disorder. Patients suffer from progressive neurodegeneration, severe bronchial complications,…”
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Erratum: Low-dose irradiation prior to bone marrow transplantation results in ATM activation and increased lethality in Atm-deficient mice
Published in Bone marrow transplantation (Basingstoke) (06-04-2016)“…Correction to: Bone Marrow Transplantation (2016) 51, 560–567; doi:10.1038/bmt.2015.334; published online 11 January 2016 Since the online publication of this…”
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Guidelines for the pathoanatomical examination of the lower brain stem in ingestive and swallowing disorders and its application to a dysphagic spinocerebellar ataxia type 3 patient
Published in Neuropathology and applied neurobiology (01-02-2003)“…U. Rüb, E. R. Brunt, D. Del Turco, R. A. I. de Vos, K. Gierga, H. Paulson and H. Braak (2003) Neuropathology and Applied Neurobiology 29, 1–13 Guildelines for…”
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NADPH Oxidase-4 Maintains Neuropathic Pain after Peripheral Nerve Injury
Published in The Journal of neuroscience (25-07-2012)Get full text
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Damage to the reticulotegmental nucleus of the pons in spinocerebellar ataxia type 1, 2, and 3
Published in Neurology (12-10-2004)“…The reticulotegmental nucleus of the pons (RTTG) is among the precerebellar nuclei of the human brainstem. Although it represents an important component of the…”
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Accumulation of phosphorylated IκBα and activated IKK in nodes of Ranvier
Published in Neuropathology and applied neurobiology (01-06-2008)“…Aims: Nuclear factor‐kappaB (NF‐κB) is an ubiquitously expressed transcription factor that modulates inducible gene transcription crucial for the regulation of…”
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Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1
Published in Science (American Association for the Advancement of Science) (21-05-2004)“…Parkinson's disease (PD) is a neurodegenerative disorder characterized by degeneration of dopaminergic neurons in the substantia nigra. We previously mapped a…”
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Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation
Published in Molecular and cellular neuroscience (01-10-2003)“…Alpha-synuclein was implicated in Parkinson's disease when missense mutations in the α-synuclein gene were found in autosomal dominant Parkinson's disease and…”
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Induction of Brain-Derived Neurotrophic Factor in Plaque-Associated Glial Cells of Aged APP23 Transgenic Mice
Published in The Journal of neuroscience (10-03-2004)“…Brain-derived neurotrophic factor (BDNF) is a versatile neurotrophic factor that has been implicated in cell survival, cell differentiation, axonal growth, and…”
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Reduced Inflammatory Hyperalgesia with Preservation of Acute Thermal Nociception in Mice Lacking cGMP-Dependent Protein Kinase I
Published in Proceedings of the National Academy of Sciences - PNAS (02-03-2004)“…cGMP-dependent protein kinase I (PKG-I) has been suggested to contribute to the facilitation of nociceptive transmission in the spinal cord presumably by…”
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Dentate Granule Cells in Reeler Mutants and VLDLR and ApoER2 Knockout Mice
Published in Experimental neurology (01-07-2002)“…We have studied the organization and cellular differentiation of dentate granule cells and their axons, the mossy fibers, in reeler mutant mice lacking reelin…”
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Lamina-specific distribution of synaptopodin, an actin-associated molecule essential for the spine apparatus, in identified principal cell dendrites of the mouse hippocampus
Published in Journal of comparative neurology (1911) (04-07-2005)“…Synaptopodin is an actin‐associated molecule found in a subset of telencephalic spines. It is an essential component of the spine apparatus, a Ca2+‐storing…”
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Laser microdissection of immunolabeled astrocytes allows quantification of astrocytic gene expression
Published in Journal of neuroscience methods (30-09-2004)“…Astrocytes represent the major glial cell population within the central nervous system. In order to elucidate the function of astrocytes under physiological…”
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