Search Results - "Turbiak, Anjanette J."

Use of Enterally Delivered Angiotensin II Type Ia Receptor Antagonists to Reduce the Severity of Colitis by Okawada, Manabu, Koga, Hiroyuki, Larsen, Scott D., Showalter, Hollis D., Turbiak, Anjanette J., Jin, Xiaohong, Lucas, Peter C., Lipka, Elke, Hillfinger, John, Kim, Jae Seung, Teitelbaum, Daniel H.

“…Background Renin-angiotensin system blockade reduces inflammation in several organ systems. Having found a fourfold increase in angiotensin II type Ia receptor…”
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Structure-Based Design of Novel Benzoxazinorifamycins with Potent Binding Affinity to Wild-Type and Rifampin-Resistant Mutant Mycobacterium tuberculosis RNA Polymerases by Gill, Sumandeep K, Xu, Hao, Kirchhoff, Paul D, Cierpicki, Tomasz, Turbiak, Anjanette J, Wan, Baojie, Zhang, Nan, Peng, Kuan-Wei, Franzblau, Scott G, Garcia, George A, Showalter, H. D. Hollis

“…By utilization of three-dimensional structure information of rifamycins bound to RNA polymerase (RNAP) and the human pregnane X receptor (hPXR), representative…”
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Investigation of 3-aryl-pyrimido[5,4-e][1,2,4]triazine-5,7-diones as small molecule antagonists of β-catenin/TCF transcription by Zeller, Jörg, Turbiak, Anjanette J., Powelson, Ian A., Lee, Surin, Sun, Duxin, Showalter, H.D. Hollis, Fearon, Eric R.

“…Nearly all colorectal cancers (CRCs) and varied subsets of other cancers have somatic mutations leading to β-catenin stabilization and increased β-catenin/TCF…”
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A novel synthesis of 3-(substituted)pyrimido[4,5- c]pyridazine-5,7(1 H,6 H)-diones by Turbiak, Anjanette J., Kampf, Jeff W., Hollis Showalter, H.D.

“…An improved synthesis of 3-(substituted)pyrimido[4,5- c]pyridazine-5,7(1 H,6 H)-diones, a known subclass of 4-deazatoxoflavins, is reported. The approach…”
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A novel synthesis of N1-(substituted)-pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-diones by Turbiak, Anjanette J., Showalter, H.D. Hollis

“…A new synthesis of N 1 -(substituted)-pyrimido[5,4- e ]-1,2,4-triazine-5,7(1 H ,6 H )-diones, which are analogues of the natural product toxoflavin, is…”
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Novel Peptide Ligands of RGS4 from a Focused One-Bead, One-Compound Library by Roof, Rebecca A, Sobczyk-Kojiro, Katarzyna, Turbiak, Anjanette J, Roman, David L, Pogozheva, Irina D, Blazer, Levi L, Neubig, Richard R, Mosberg, Henry I

“…Regulators of G protein signaling accelerate GTP hydrolysis by Gα subunits and profoundly inhibit signaling by G protein-coupled receptors. The distinct…”
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A novel synthesis of N(1)-(substituted)-pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-diones by Turbiak, Anjanette J, Showalter, H D Hollis

“…A new synthesis of N(1)-(substituted)-pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-diones, which are analogues of the natural product toxoflavin, is reported…”
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A novel synthesis of N 1-(substituted)-pyrimido[5,4- e]-1,2,4-triazine-5,7(1 H,6 H)-diones by Turbiak, Anjanette J., Showalter, H.D. Hollis

“…A new synthesis of N 1-(substituted)-pyrimido[5,4- e]-1,2,4-triazine-5,7(1 H,6 H)-diones, which are analogues of the natural product toxoflavin, is reported…”
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Wnt-Pathway Directed Compound Targets Blast Crisis and Chronic Phase CML Leukemia Stem Progenitors by Peterson, Luke F, Turbiak, Anjanette J, Giannola, Diane M, Donato, Nicholas, Showalter, Hollis H.D., Fearon, Eric R, Talpaz, Moshe

“…Abstract 2168 Poster Board II-145 The deregulated tyrosine kinase associated with t(9;22) fusion protein BCR-ABL is efficiently targeted by tyrosine kinase…”
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The synthesis and exploration of potential new antagonists of the Wnt signaling pathway: New leads to treat colon cancer? Or, not quite? by Turbiak, Anjanette J

“…Colorectal cancer continues to be a major health concern with over 150,000 new cases diagnosed each year in the United States alone. Nonetheless, the mutations…”
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The synthesis and exploration of potential new antagonists of the Wnt signaling pathway: New leads to treat colon cancer? Or, not quite? by Turbiak, Anjanette J

“…Colorectal cancer continues to be a major health concern with over 150,000 new cases diagnosed each year in the United States alone. Nonetheless, the mutations…”
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