Search Results - "Turani, Ornella"
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Caenorhabditis elegans muscle Cys-loop receptors as novel targets of terpenoids with potential anthelmintic activity
Published in PLoS neglected tropical diseases (01-11-2019)“…The anthelmintic treatment of nematode infections remains the pillar of worm control in both human and veterinary medicine. Since control is threatened by the…”
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Regulation of nicotinic acetylcholine receptors by post-translational modifications
Published in Pharmacological research (01-04-2023)“…Nicotinic acetylcholine receptors (nAChRs) comprise a family of pentameric ligand-gated ion channels widely distributed in the central and peripheric nervous…”
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The diverse family of Cys-loop receptors in Caenorhabditis elegans: insights from electrophysiological studies
Published in Biophysical reviews (01-08-2023)“…Cys-loop receptors integrate a large family of pentameric ligand-gated ion channels that mediate fast ionotropic responses in vertebrates and invertebrates…”
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A New Antagonist of Caenorhabditis elegans Glutamate-Activated Chloride Channels With Anthelmintic Activity
Published in Frontiers in neuroscience (19-08-2020)“…Nematode parasitosis causes significant mortality and morbidity in humans and considerable losses in livestock and domestic animals. The acquisition of…”
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Activation of Caenorhabditis elegans Levamisole-Sensitive and Mammalian Nicotinic Receptors by the Antiparasitic Bephenium
Published in Molecular pharmacology (01-11-2018)“…Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels involved in neuromuscular transmission. In nematodes, muscle nAChRs are targets of…”
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Rhythms in lipid droplet content driven by a metabolic oscillator are conserved throughout evolution
Published in Cellular and molecular life sciences : CMLS (01-12-2024)“…The biological clock in eukaryotes controls daily rhythms in physiology and behavior. It displays a complex organization that involves the molecular…”
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Potent Anthelmintic Activity of Chalcones Synthesized by an Effective Green Approach
Published in ChemMedChem (02-07-2024)“…There is currently an urgent need for new anthelmintic agents due to increasing resistance to the limited available drugs. The chalcone scaffold is a…”
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