Search Results - "Tuppurainen, K."

Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis by LAIHO, P, KOKKO, A, SCHWARTZ, S, ARANGO, D, MÄKINEN, M. J, AALTONEN, L. A, VANHARANTA, S, SALOVAARA, R, SAMMALKORPI, H, JARVINEN, H, MECKLIN, J.-P, KARTTUNEN, T. J, TUPPURAINEN, K, DAVALOS, V

“…Serrated colorectal carcinomas (CRCs) are morphologically different from conventional CRCs and have been proposed to follow a distinct pathway of CRC…”
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Chemical inhibition of PCDD/F formation in incineration processes by Ruokojärvi, Päivi H, Asikainen, Arja H, Tuppurainen, Kari A, Ruuskanen, Juhani

“…This review summarises results of our pilot-scale experiments to find suitable inhibitors for preventing the formation of polychlorinated dibenzo- p-dioxins…”
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No evidence of somatic aryl hydrocarbon receptor interacting protein mutations in sporadic endocrine neoplasia by Raitila, A, Georgitsi, M, Karhu, A, Tuppurainen, K, Mäkinen, M J, Birkenkamp-Demtröder, K, Salmenkivi, K, Ørntoft, T F, Arola, J, Launonen, V, Vahteristo, P, Aaltonen, L A

“…Germline mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene were recently observed in patients with pituitary adenoma predisposition…”
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Effect of urea on fly ash PCDD/F concentrations in different particle sizes by Ruokojärvi, P, Aatamila, M, Tuppurainen, K, Ruuskanen, J

“…The effect of urea as an inhibitor for reducing polychlorinated dibenzo- p-dioxin and dibenzofuran (PCDD/F) concentrations in flue gases was studied in a pilot…”
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EEVA (Electronic Eigenvalue): A New QSAR/QSPR Descriptor for Electronic Substituent Effects Based on Molecular Orbital Energies by Tuppurainen, K.

“…A new descriptor of molecular structure for use in the derivation of predictive QSAR and QSPR models. EEVA, is described. EEVA (Electronic Eigen Value) is a…”
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Cryotherapy for eyelid and periocular basal cell carcinomas : outcome in 166 cases over an 8-year period by TUPPURAINEN, K

“…Basal cell carcinoma (BCC) is the most common of all malignant tumours and often appears on the periocular skin. In the present study, patients with 166 eyelid…”
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Performance of (consensus) kNN QSAR for predicting estrogenic activity in a large diverse set of organic compounds by Asikainen, A.H., Ruuskanen, J., Tuppurainen, K.A.

“…A novel method (in the context of quantitative structure-activity relationship (QSAR)) based on the k nearest neighbour (kNN) principle, has recently been…”
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Aryl hydrocarbon receptor interacting protein mutations seem not to associate with familial non-medullary thyroid cancer by Raitila, A., Georgitsi, M., Bonora, E., Vargiolu, M., Tuppurainen, K., Mäkinen, M. J., Vierimaa, O., Salmela, P. I., Launonen, V., Vahteristo, P., Aaltonen, L. A., Romeo, G., Karhu, Auli

“…Background : Over 95% of all thyroid malignancies are non-medullary thyroid carcinomas (NMTC). Familial NMTC are more aggressive and mortality is higher as…”
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A Plausible Mechanism for the Mutagenic Activity (Salmonella typhimurium TA100) of MX Compounds: A Formation of CG-CG+-CG Radical Cation by One-electron Reduction by Tuppurainen, K.

“…Combining our previous QSAR work with recent high-level quantum mechanical calculations, a plausible mechanism for the mutagenic activity of halogenated…”
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Performance of multicomponent self-organizing regression (MCSOR) in QSAR, QSPR, and multivariate calibration: comparison with partial least-squares (PLS) and validation with large external data sets by Tuppurainen, K., Korhonen, S.-P., Ruuskanen, J.

“…A novel method for underdetermined regression problems, multicomponent self-organizing regression (MCSOR), has been recently introduced. Here, its performance…”
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Alternative QSAR models for selected estradiol and cytochrome P450 ligands: comparison between classical, spectroscopic, CoMFA and GRID/GOLPE methods by Asikainen, A. H., Ruuskanen, J., Tuppurainen, K. A.

“…The performance of the spectroscopic EVA (eigenvalue) and EEVA (electronic eigenvalue) methods was tested with data sets applying coumarin 7-hydroxylation…”
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The essential role of BRAF and KRAS mutations in colorectal serrated adenocarcinoma by Pukkila, L, Tuppurainen, K, Karttunen, T.J, Mäkinen, M.J

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Characterisation of the chemical and biological properties of molecules with QSAR/QSPR and chemical grouping, and its application to a group of alkyl ethers by Niska, H., Tuppurainen, K., Skön, J.-P., Mallett, A.K., Kolehmainen, M.

“…This study presents a QSAR/QSPR modelling and chemical grouping (read-across) approach to provide information on the biological properties of a group of…”
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Improving the performance of SOMFA by use of standard multivariate methods by Korhonen, S.-P., Tuppurainen, K., Laatikainen, R., Peräkylä, M.

“…Self-Organizing Molecular Field Analysis (SOMFA) comes with a built-in regression methodology, the Self-Organizing Regression (SOR), instead of relying on…”
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RWD109 The Burden of R/R DLBCL in Finland: PFS of The First-Line Immunochemotherapy and HCRU of The Patients Diagnosed in 2015–2017 in The Hospital District of Southwest Finland by Koski, L, Tuominen, S, Uusi-Rauva, K, Blom, T, Tuppurainen, K, Alanne, E

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Zinc removal in anaerobic sulphate-reducing liquid substrate process by Tuppurainen, K.O, Väisänen, A.O, Rintala, J.A

“…Zinc and sulphate removal from synthetic wastewater was investigated by using four laboratory parallel upflow-mode reactors (referred as R1 to R4; R1 contained…”
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The modulation of protein synthesis by T3 in Caco-2 colorectal cancer cells – the role of nuclear targeting of TR receptors by Kantola, T, Tuppurainen, K, Hörkkö, T, Karttunen, T.J, Eskelinen, S, Mäkinen, M.J

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Effect of catalysts and chlorine source on the formation of organic chlorinated compounds by Halonen, I., Tarhanen, J., Ruokojärvi, P., Tuppurainen, K., Ruuskanen, J.

“…Two series of catalyzed incineration tests were performed in a 32 kW laboratory pilot plant to study the effect of metal catalysts on the formation of…”
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Sulphate-Reducing Laboratory-Scale High-Rate Anaerobic Reactors for Treatment of Metal- and Sulphate-Containing Mine Wastewater by Tuppurainen, K. O., Väisänen, A. O., Rintala, J. A.

“…Upflow anaerobic sludge blanket (UASB) reactors were used in this study to evaluate the feasibility of the sulphate-reducing, anaerobic high-rate process to…”
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Methods for imputation of missing values in air quality data sets by Junninen, Heikki, Niska, Harri, Tuppurainen, Kari, Ruuskanen, Juhani, Kolehmainen, Mikko

“…Methods for data imputation applicable to air quality data sets were evaluated in the context of univariate (linear, spline and nearest neighbour…”
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