Search Results - "Tupper, Joanna"

From bench to bedside for gene-directed enzyme prodrug therapy of cancer by Dachs, Gabi U., Tupper, Joanna, Tozer, Gillian M.

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From bench to bedside for gene-directed enzyme prodrug therapy of cancer by Dachs, Gabi U, Tupper, Joanna, Tozer, Gillian M

“…Gene therapy of cancer offers the possibility of a targeted treatment that destroys tumors and metastases, but not normal tissues. In gene-directed enzyme…”
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Nociceptin and the ORL‐1 ligand [Phe 1 ψ (CH 2 ‐NH)Gly 2 ]nociceptin(1‐13)NH 2 exert anti‐opioid effects in the Freund's adjuvant‐induced arthritic rat model of chronic pain by Bertorelli, Rosalia, Corradini, Laura, Rafiq, Kamran, Tupper, Joanna, Calò, Girolamo, Ongini, Ennio

“…Stimulation of the opioid receptor‐like1 (ORL‐1) receptor by nociceptin (NC) produces hyperalgesia and reverses the antinociceptive effects induced by opioids…”
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Nociceptin and the ORL‐1 ligand [Phe1ψ (CH2‐NH)Gly2]nociceptin(1‐13)NH2 exert anti‐opioid effects in the Freund's adjuvant‐induced arthritic rat model of chronic pain by Bertorelli, Rosalia, Corradini, Laura, Rafiq, Kamran, Tupper, Joanna, Calò, Girolamo, Ongini, Ennio

“…Stimulation of the opioid receptor‐like1 (ORL‐1) receptor by nociceptin (NC) produces hyperalgesia and reverses the antinociceptive effects induced by opioids…”
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Analysis of the horseradish peroxidase indole-3-acetic acid combination in a three-dimensional tumor model by Tupper, Joanna, Greco, Olga, Tozer, Gillian M, Dachs, Gabi U

“…Horseradish peroxidase has previously been shown to catalyze the conversion of indole-3-acetic acid (IAA) to a potent cytotoxin in a gene therapy setting. A…”
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Use of horseradish peroxidase for gene directed enzyme prodrug therapy by Tupper, Joanna

“…Gene directed enzyme prodrug therapy (GDEPT) is a form of targeted cancer therapy, where an enzyme is used to create a cytotoxin from a prodrug specifically…”
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