Search Results - "Tuomisto, Johanna"
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The complexity of T cell–mediated penicillin hypersensitivity reactions
Published in Allergy (Copenhagen) (01-01-2021)“…Penicillin refers to a group of beta‐lactam antibiotics that are the first‐line treatment for a range of infections. However, they also possess the ability to…”
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Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4 + regulatory T cells by regulating IL2RA
Published in Proceedings of the National Academy of Sciences - PNAS (04-06-2024)“…Regulatory T cells (Tregs) are central in controlling immune responses, and dysregulation of their function can lead to autoimmune disorders or cancer. Despite…”
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The allopurinol metabolite, oxypurinol, drives oligoclonal expansions of drug-reactive T cells in resolved hypersensitivity cases and drug-naïve healthy donors
Published in Allergy (Copenhagen) (01-11-2023)“…Allopurinol (ALP) is a successful drug used in the treatment of gout. However, this drug has been implicated in hypersensitivity reactions that can cause…”
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Transcriptional Repressor HIC1 Contributes to Suppressive Function of Human Induced Regulatory T Cells
Published in Cell reports (Cambridge) (20-02-2018)“…Regulatory T (Treg) cells are critical in regulating the immune response. In vitro induced Treg (iTreg) cells have significant potential in clinical medicine…”
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