Search Results - "Tuomela, Tea"

Nuclear genetic background influences the phenotype of the Drosophila tko25t mitochondrial protein-synthesis mutant by Jacobs, Howard T, Tuomela, Tea, Lillsunde, Päivi

“…Abstract The Drosophila tko25t point mutation in the gene encoding mitoribosomal protein S12 produces a complex phenotype of multiple respiratory chain…”
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Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila by Vesala, Laura, Basikhina, Yuliya, Tuomela, Tea, Nurminen, Anssi, Siukola, Emilia, Vale, Pedro F, Salminen, Tiina S

“…Mitochondria participate in various cellular processes including energy metabolism, apoptosis, autophagy, production of reactive oxygen species, stress…”
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Polyadenylation and degradation of structurally abnormal mitochondrial tRNAs in human cells by Toompuu, Marina, Tuomela, Tea, Laine, Pia, Paulin, Lars, Dufour, Eric, Jacobs, Howard T

“…Abstract RNA 3′ polyadenylation is known to serve diverse purposes in biology, in particular, regulating mRNA stability and translation. Here we determined…”
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Mitochondrial Dysfunction Plus High-Sugar Diet Provokes a Metabolic Crisis That Inhibits Growth by Kemppainen, Esko, George, Jack, Garipler, Görkem, Tuomela, Tea, Kiviranta, Essi, Soga, Tomoyoshi, Dunn, Cory D, Jacobs, Howard T

“…The Drosophila mutant tko25t exhibits a deficiency of mitochondrial protein synthesis, leading to a global insufficiency of respiration and oxidative…”
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Expression of the Ciona intestinalis Alternative Oxidase (AOX) in Drosophila Complements Defects in Mitochondrial Oxidative Phosphorylation by Fernandez-Ayala, Daniel J.M., Sanz, Alberto, Vartiainen, Suvi, Kemppainen, Kia K., Babusiak, Marek, Mustalahti, Eero, Costa, Rodolfo, Tuomela, Tea, Zeviani, Massimo, Chung, Jongkyeong, O'Dell, Kevin M.C., Rustin, Pierre, Jacobs, Howard T.

“…Defects in mitochondrial OXPHOS are associated with diverse and mostly intractable human disorders. The single-subunit alternative oxidase (AOX) found in many…”
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Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction by Sanz, Alberto, Soikkeli, Mikko, Portero-Otín, Manuel, Wilson, Angela, Kemppainen, Esko, McIlroy, George, Ellilä, Simo, Kemppainen, Kia K, Tuomela, Tea, Lakanmaa, Matti, Kiviranta, Essi, Stefanatos, Rhoda, Dufour, Eric, Hutz, Bettina, Naudí, Alba, Jové, Mariona, Zeb, Akbar, Vartiainen, Suvi, Matsuno-Yagi, Akemi, Yagi, Takao, Rustin, Pierre, Pamplona, Reinald, Jacobs, Howard T

“…Mutations in mitochondrial oxidative phosphorylation complex I are associated with multiple pathologies, and complex I has been proposed as a crucial regulator…”
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Mitochondrial dysfunction generates a growth-restraining signal linked to pyruvate in Drosophila larvae by George, Jack, Tuomela, Tea, Kemppainen, Esko, Nurminen, Antti, Braun, Samuel, Yalgin, Cagri, Jacobs, Howard T.

“…The Drosophila bang-sensitive mutant tko 25t , manifesting a global deficiency in oxidative phosphorylation due to a mitochondrial protein synthesis defect,…”
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Correction: Mitochondrial Dysfunction Plus High-Sugar Diet Provokes a Metabolic Crisis That Inhibits Growth by Kemppainen, Esko, George, Jack, Garipler, Görkem, Tuomela, Tea, Kiviranta, Essi, Soga, Tomoyoshi, Dunn, Cory D, Jacobs, Howard T

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Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease by Vartiainen, Suvi, Chen, Shanjun, George, Jack, Tuomela, Tea, Luoto, Kaisa R, O'Dell, Kevin M C, Jacobs, Howard T

“…A point mutation in the Drosophila gene that codes for the major adult isoform of adenine nuclear translocase (ANT) represents a model for human diseases that…”
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A naturally occurring mitochondrial genome variant confers broad protection from infection in Drosophila by Salminen, Tiina S., Vesala, Laura, Basikhina, Yuliya, Kutzer, Megan, Tuomela, Tea, Lucas, Ryan, Monteith, Katy, Prakash, Arun, Tietz, Tilman, Vale, Pedro F.

“…The role of mitochondria in immunity is increasingly recognized, but it is unclear how variation in mitochondrial DNA (mtDNA) contributes to variable infection…”
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Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency by Kemppainen, Kia K, Rinne, Juho, Sriram, Ashwin, Lakanmaa, Matti, Zeb, Akbar, Tuomela, Tea, Popplestone, Anna, Singh, Satpal, Sanz, Alberto, Rustin, Pierre, Jacobs, Howard T

“…Mitochondrial dysfunction is a significant factor in human disease, ranging from systemic disorders of childhood to cardiomyopathy, ischaemia and…”
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Ciona intestinalis NADH dehydrogenase NDX confers stress-resistance and extended lifespan on Drosophila by Gospodaryov, Dmytro V., Lushchak, Oleh V., Rovenko, Bohdana M., Perkhulyn, Natalia V., Gerards, Mike, Tuomela, Tea, Jacobs, Howard T.

“…An assembled cDNA coding for the putative single-subunit NADH dehydrogenase (NDX) of Ciona intestinalis was introduced into Drosophila melanogaster. The…”
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Alternative oxidase confers nutritional limitation on Drosophila development by Saari, Sina, Kemppainen, Esko, Tuomela, Tea, Oliveira, Marcos T., Dufour, Eric, Jacobs, Howard T.

“…The mitochondrial alternative oxidase, AOX, present in most eukaryotes apart from vertebrates and insects, catalyzes the direct oxidation of ubiquinol by…”
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β carbonic anhydrase is required for female fertility in Drosophila melanogaster by Syrjänen, Leo, Valanne, Susanna, Kuuslahti, Marianne, Tuomela, Tea, Sriram, Ashwin, Sanz, Alberto, Jacobs, Howard T, Rämet, Mika, Parkkila, Seppo

“…BACKGROUND: Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous enzymes that catalyze the reversible hydration reaction of carbon dioxide. CAs are present as…”
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carbonic anhydrase is required for female fertility in Drosophila melanogaster by Syrjänen, Leo, Valanne, Susanna, Kuuslahti, Marianne, Tuomela, Tea, Sriram, Ashwin, Sanz, Alberto, Jacobs, Howard T, Rämet, Mika, Parkkila, Seppo

“…Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous enzymes that catalyze the reversible hydration reaction of carbon dioxide. CAs are present as six…”
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S14.9 Testing the mitochondrial free radical theory of aging in Drosophila melanogaster by Sanz, Alberto, Babusiakova, Emilia, Tuomela, Tea, Mustalahti, Eero, Fernandez-Ayala, Daniel J.M., Jacobs, Howy

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S12.34 The alternative oxidase as a tool to study mitochondrial function and to correct mitochondrial pathologies by Sanz, Alberto, Mustalahti, Eero, Babusiakova, Emilia, Tuomela, Tea, Vartianen, Suvi, Fernandez-Ayala, Daniel J.M., Jacobs, Howy

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