Search Results - "Tuomanen, E. I."

IgG1+ B‐cell immunity predates IgE responses in epicutaneous sensitization to foods by Jiménez‐Saiz, R., Ellenbogen, Y., Koenig, J. F. E., Gordon, M. E., Walker, T. D., Rosace, D., Spill, P., Bruton, K., Kong, J., Monteiro, K., Wen, J., Tuomanen, E. I., Kolbeck, R., Chu, D. K., Waserman, S., Jordana, M.

“…Background The generation of IgE‐mediated food allergy in humans is silent and only diagnosed upon manifestation of clinical symptoms. While experimental…”
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Responsiveness to a pandemic alert: use of reverse genetics for rapid development of influenza vaccines by Webby, RJ, Perez, DR, Coleman, JS, Guan, Y, Knight, JH, Govorkova, EA, McClain-Moss, LR, Peiris, JS, Rehg, JE, Tuomanen, EI, Webster, RG

“…In response to the emergence of severe infection capable of rapid global spread, WHO will issue a pandemic alert. Such alerts are rare; however, on Feb 19,…”
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Reprogramming the Host Response in Bacterial Meningitis: How Best To Improve Outcome? by VAN DER FLIER, M, GEELEN, S. P. M, KLMPEN, J. L. L, HOEPELMAN, I. M, TUOMANEN, E. I

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Pneumococcal trafficking across the blood-brain barrier. Molecular analysis of a novel bidirectional pathway by Ring, A, Weiser, J N, Tuomanen, E I

“…Although Streptococcus pneumoniae is a major cause of meningitis in humans, the mechanisms underlying its traversal from the circulation across the blood-brain…”
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Role of Novel Choline Binding Proteins in Virulence of Streptococcus pneumoniae by GOSINK, Khoosheh K, MANN, Elizabeth R, GUGLIELMO, Chris, TUOMANEN, Elaine I, MASURE, H. Robert

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Neuroprotection by a caspase inhibitor in acute bacterial meningitis by Tuomanen, E.I, Braun, J.S, Novak, R, Herzog, K.-H, Bodner, S.M, Cleveland, J.L

“…Half of the survivors of bacterial meningitis experience motor deficits, seizures, hearing loss or cognitive impairment, despite adequate bacterial killing by…”
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Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor by Cundell, Diana R, Gerard, Norma P, Gerard, Craig, Idanpaan-Heikkila, Ilona, Tuomanen, Elaine I

“…The Gram-positive bacterium Streptococcus pneumoniae is a major cause of pneumonia, sepsis and meningitis. Although the invasive disease is severe, some 40% of…”
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The pneumococcus: epidemiology, microbiology, and pathogenesis by Henriques-Normark, Birgitta, Tuomanen, Elaine I

“…The pneumococcus is the classic Gram-positive extracellular pathogen. The medical burden of diseases it causes is amongst the greatest in the world. Intense…”
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Relationship between colonial morphology and adherence of Streptococcus pneumoniae by CUNDELL, D. R, WEISER, J. N, SHEN, J, YOUNG, A, TUOMANEN, E. I

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Apoptosis-Inducing Factor Mediates Microglial and Neuronal Apoptosis Caused by Pneumococcus by Braun, Johann S., Novak, Rodger, Murray, Peter J., Eischen, Christine M., Susin, Santos A., Kroemer, Guido, Halle, Annett, Weber, Joerg R., Tuomanen, Elaine I., Cleveland, John L.

“…Streptococcus pneumoniae is the major cause of bacterial meningitis and it damages the hippocampus by inducing neuronal apoptosis. The blocking of caspases…”
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Consequences of microbial attachment: directing host cell functions with adhesins by HOEPELMAN, A. I. M, TUOMANEN, E. I

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Reduction of inflammation, tissue damage, and mortality in bacterial meningitis in rabbits treated with monoclonal antibodies against adhesion-promoting receptors of leukocytes by TUOMANEN, E. I, SAUKKONEN, K, SANDE, S, CIOFFE, C, WRIGHT, S. D

“…We tested if specific inhibition of recruitment of leukocytes across the blood brain barrier from the vascular compartment to the cerebrospinal fluid (CSF)…”
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Adherence of Streptococcus pneumoniae to immobilized fibronectin by VAN DER FLIER, M, NOK CHHUN, WIZEMANN, T. M, MIN, J, MCCARTHY, J. B, TUOMANEN, E. I

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Relationship between phase variation in colony morphology, intrastrain variation in cell wall physiology, and nasopharyngeal colonization by Streptococcus pneumoniae by WEISER, J. N, MARKIEWICZ, Z, TUOMANEN, E. I, WANI, J. H, O'BRIEN, A

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Identification of a carbohydrate recognition domain in filamentous hemagglutinin from Bordetella pertussis by PRASAD, S. M, YIBING YIN, RODZINSKI, E, TUOMANEN, E. I, MASURE, H. R

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The biology of pneumococcal infection by TUOMANEN, E. I

“…For 100 y, the study of the molecular mechanism of pneumococcal infection has richly rewarded biomedical science and pediatrics. More recently, a framework has…”
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Tissue-Specific Contributions of Pneumococcal Virulence Factors to Pathogenesis by Orihuela, Carlos J., Gao, Geli, Francis, Kevin P., Yu, Jun, Tuomanen, Elaine I.

“…We assessed the ability of Streptococcus pneumoniae mutants deficient in either choline binding protein A (CbpA), pneumolysin (Pln), pyruvate oxidase (SpxB),…”
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Pertussis Toxin has Eukaryotic-Like Carbohydrate Recognition Domains by Saukkonen, Kirsi, Burnette, W. Neal, Mar, Vernon L., Masure, H. Robert, Tuomanen, Elaine I.

“…Bordetella pertussis is bound to glycoconjugates on human cilia and macrophages by multiple adhesins, including pertussis toxin. The cellular recognition…”
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Role of carbohydrate recognition domains of pertussis toxin in adherence of Bordetella pertussis to human macrophages by VAN'T WOUT, J, BURNETTE, W. N, MAR, V. L, ROZDZINSKI, E, WRIGHT, S. D, TUOMANEN, E. I

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The Molecular Basis of Pneumococcal Infection: A Hypothesis by Cundell, Diana, Masnre, H. Robert, Tuomanen, Elaine I.

“…Newinsight has been gained into the mechanisms underlying the tissue tropism and inflammation of pneumococcal infection. Virulence has been linked to a…”
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