Search Results - "Tuohy, Kieran M"

The gut microbiota and host health: a new clinical frontier by Marchesi, Julian R, Adams, David H, Fava, Francesca, Hermes, Gerben D A, Hirschfield, Gideon M, Hold, Georgina, Quraishi, Mohammed Nabil, Kinross, James, Smidt, Hauke, Tuohy, Kieran M, Thomas, Linda V, Zoetendal, Erwin G, Hart, Ailsa

“…Over the last 10-15 years, our understanding of the composition and functions of the human gut microbiota has increased exponentially. To a large extent, this…”
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Low-grade inflammation, diet composition and health: current research evidence and its translation by Minihane, Anne M., Vinoy, Sophie, Russell, Wendy R., Baka, Athanasia, Roche, Helen M., Tuohy, Kieran M., Teeling, Jessica L., Blaak, Ellen E., Fenech, Michael, Vauzour, David, McArdle, Harry J., Kremer, Bas H. A., Sterkman, Luc, Vafeiadou, Katerina, Benedetti, Massimo Massi, Williams, Christine M., Calder, Philip C.

“…The importance of chronic low-grade inflammation in the pathology of numerous age-related chronic conditions is now clear. An unresolved inflammatory response…”
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Two apples a day lower serum cholesterol and improve cardiometabolic biomarkers in mildly hypercholesterolemic adults: a randomized, controlled, crossover trial by Koutsos, Athanasios, Riccadonna, Samantha, Ulaszewska, Maria M, Franceschi, Pietro, Trošt, Kajetan, Galvin, Amanda, Braune, Tanya, Fava, Francesca, Perenzoni, Daniele, Mattivi, Fulvio, Tuohy, Kieran M, Lovegrove, Julie A

“…Apples are rich in bioactive polyphenols and fiber. Evidence suggests that consumption of apples or their bioactive components is associated with beneficial…”
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‘The way to a man's heart is through his gut microbiota’ – dietary pro- and prebiotics for the management of cardiovascular risk by Tuohy, Kieran M., Fava, Francesca, Viola, Roberto

“…The human gut microbiota has been identified as a possible novel CVD risk factor. This review aims to summarise recent insights connecting human gut microbiome…”
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Apples and cardiovascular health--is the gut microbiota a core consideration? by Koutsos, Athanasios, Tuohy, Kieran M, Lovegrove, Julie A

“…There is now considerable scientific evidence that a diet rich in fruits and vegetables can improve human health and protect against chronic diseases. However,…”
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Towards microbial fermentation metabolites as markers for health benefits of prebiotics by Verbeke, Kristin A., Boobis, Alan R., Chiodini, Alessandro, Edwards, Christine A., Franck, Anne, Kleerebezem, Michiel, Nauta, Arjen, Raes, Jeroen, van Tol, Eric A. F., Tuohy, Kieran M.

“…Available evidence on the bioactive, nutritional and putative detrimental properties of gut microbial metabolites has been evaluated to support a more…”
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The Prebiotic Effects of Oats on Blood Lipids, Gut Microbiota, and Short-Chain Fatty Acids in Mildly Hypercholesterolemic Subjects Compared With Rice: A Randomized, Controlled Trial by Xu, Dengfeng, Feng, Meiyuan, Chu, YiFang, Wang, Shaokang, Shete, Varsha, Tuohy, Kieran M, Liu, Feng, Zhou, Xirui, Kamil, Alison, Pan, Da, Liu, Hechun, Yang, Xian, Yang, Chao, Zhu, Baoli, Lv, Na, Xiong, Qian, Wang, Xin, Sun, Jianqin, Sun, Guiju, Yang, Yuexin

“…Phytochemicals derived from oats are reported to possess a beneficial effect on modulating dyslipidemia, specifically on lowering total and LDL cholesterol…”
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Obesity and the gut microbiota: does up-regulating colonic fermentation protect against obesity and metabolic disease? by Conterno, Lorenza, Fava, Francesca, Viola, Roberto, Tuohy, Kieran M

“…Obesity is now considered a major public health concern globally as it predisposes to a number of chronic human diseases. Most developed countries have…”
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The effect of high-polyphenol Mediterranean diet on visceral adiposity: the DIRECT PLUS randomized controlled trial by Zelicha, Hila, Kloting, Nora, Kaplan, Alon, Yaskolka Meir, Anat, Rinott, Ehud, Tsaban, Gal, Chassidim, Yoash, Bluher, Matthias, Ceglarek, Uta, Isermann, Berend, Stumvoll, Michael, Quayson, Rita Nana, von Bergen, Martin, Engelmann, Beatrice, Rolle-Kampczyk, Ulrike E., Haange, Sven-Bastiaan, Tuohy, Kieran M., Diotallevi, Camilla, Shelef, Ilan, Hu, Frank B., Stampfer, Meir J., Shai, Iris

“…Abstract Background Mediterranean (MED) diet is a rich source of polyphenols, which benefit adiposity by several mechanisms. We explored the effect of the…”
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Whole-grain wheat breakfast cereal has a prebiotic effect on the human gut microbiota: a double-blind, placebo-controlled, crossover study by Costabile, Adele, Klinder, Annett, Fava, Francesca, Napolitano, Aurora, Fogliano, Vincenzo, Leonard, Clare, Gibson, Glenn R., Tuohy, Kieran M.

“…Epidemiological studies have shown an inverse association between dietary intake of whole grains and the risk of chronic disease. This may be related to the…”
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Gut microbial metabolism of bile acids modifies the effect of Mediterranean diet interventions on cardiometabolic risk in a randomized controlled trial by Gao, Peipei, Rinott, Ehud, Dong, Danyue, Mei, Zhendong, Wang, Fenglei, Liu, Yuxi, Kamer, Omer, Yaskolka Meir, Anat, Tuohy, Kieran M., Blüher, Matthias, Stumvoll, Michael, Stampfer, Meir J., Shai, Iris, Wang, Dong D.

“…Bile acids (BAs) undergo extensive microbial metabolism in the gut and exert hormone-like functions on physiological processes underlying metabolic risk…”
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Differential induction of apoptosis in human colonic carcinoma cells (Caco-2) by Atopobium, and commensal, probiotic and enteropathogenic bacteria: Mediation by the mitochondrial pathway by Altonsy, Mohammed O., Andrews, Simon C., Tuohy, Kieran M.

“…The induction of apoptosis in mammalian cells by bacteria is well reported. This process may assist infection by pathogens whereas for non-pathogens apoptosis…”
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Differential effects of two fermentable carbohydrates on central appetite regulation and body composition by Arora, Tulika, Loo, Ruey Leng, Anastasovska, Jelena, Gibson, Glenn R, Tuohy, Kieran M, Sharma, Raj Kumar, Swann, Jonathan R, Deaville, Eddie R, Sleeth, Michele L, Thomas, E Louise, Holmes, Elaine, Bell, Jimmy D, Frost, Gary

“…Obesity is rising at an alarming rate globally. Different fermentable carbohydrates have been shown to reduce obesity. The aim of the present study was to…”
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Production of conjugated linoleic acid (CLA): effect of inulin on microbial composition and CLA concentration in a human intestinal model by Carafa, Ilaria, Masuero, Domenico, Vrhovsek, Urska, Bittante, Giovanni, Franciosi, Elena, Tuohy, Kieran M.

“…Conjugated linoleic acids (CLAs) show a number of putative health-promoting activities including anti-carcinogenic, anti-adipogenic, anti-diabetogenic,…”
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Ex vivo fecal fermentation of human ileal fluid collected after raspberry consumption modifies (poly)phenolics and modulates genoprotective effects in colonic epithelial cells by Dobani, Sara, Latimer, Cheryl, McDougall, Gordon J., Allwood, J. William, Pereira-Caro, Gema, Moreno-Rojas, José Manuel, Ternan, Nigel G., Pourshahidi, L. Kirsty, Lawther, Roger, Tuohy, Kieran M., Del Rio, Daniele, O'Connor, Gloria, Rowland, Ian, Almutairi, Tahani Mazyad, Crozier, Alan, Gill, Chris I.R.

“…Diets rich in fruit and vegetables are associated with a decreased incidence of colorectal cancer (CRC) due, in part, to the bioactive (poly)phenolic…”
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Connecting the immune system, systemic chronic inflammation and the gut microbiome: The role of sex by Rizzetto, Lisa, Fava, Francesca, Tuohy, Kieran M., Selmi, Carlo

“…Unresolved low grade systemic inflammation represents the underlying pathological mechanism driving immune and metabolic pathways involved in autoimmune…”
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Effects of Resistant Starch Type III Polymorphs on Human Colon Microbiota and Short Chain Fatty Acids in Human Gut Models by Lesmes, Uri, Beards, Emma J, Gibson, Glenn R, Tuohy, Kieran M, Shimoni, Eyal

“…This study probed the possible effects of type III resistant starch (RS) crystalline polymorphism on RS fermentability by human gut microbiota and the short…”
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Using probiotics and prebiotics to improve gut health by Tuohy, Kieran M, Probert, Hollie M, Smejkal, Chris W, Gibson, Glann R

“…Recent molecular-based investigations have confirmed the species diversity and metabolic complexity of the human gut microbiota. It is also increasingly clear…”
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Metabolism of Maillard reaction products by the human gut microbiota - implications for health by Tuohy, Kieran M., Hinton, Davinia J. S., Davies, Sarah J., Crabbe, M. James C., Gibson, Glenn R., Ames, Jennifer M.

“…The human colonic microbiota imparts metabolic versatility on the colon, interacts at many levels in healthy intestinal and systemic metabolism, and plays…”
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In vitro fermentation characteristics of whole grain wheat flakes and the effect of toasting on prebiotic potential by Connolly, Michael L, Lovegrove, Julie A, Tuohy, Kieran M

“…Population studies have shown a positive correlation between diets rich in whole grains and a reduced risk of developing metabolic diseases, like diabetes,…”
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