Search Results - "Tunon, Arnulfo"

Blood brain barrier disruption in cerebral malaria: Beyond endothelial cell activation by Tunon-Ortiz, Arnulfo, Lamb, Tracey J

“…Despite Plasmodium parasites being blood restricted, the BBB becomes disrupted when the brain microvascular endothelial cells (BMECs) lining the…”
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Kynurenine pathway metabolic balance influences microglia activity: Targeting kynurenine monooxygenase to dampen neuroinflammation by Garrison, Allison M., Parrott, Jennifer M., Tuñon, Arnulfo, Delgado, Jennifer, Redus, Laney, O’Connor, Jason C.

“…•KMO inhibition attenutates specific elements of microglia activation.•Primary KMO -/- microglia recapitulate pharmacologic inhibition of KMO.•Kynurenine…”
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Author response to: Modulating kynurenine monooxygenase in microglia: The need for further characterization by Garrison, Allison M., Parrott, Jennifer M., Tunon, Arnulfo, Delgado, Jennifer, Redus, Laney, O’Connor, Jason C.

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Role of Astrocyte Activation in Experimental Cerebral Malaria by Tunon-Ortiz, Arnulfo B.N., King, Thayer P., Mimche, Patrice N., Lamb, Tracey J.

“…Cerebral malaria (CM) is a severe complication of Plasmodium falciparum (Pf) with a high lethality rate. Key features at the cellular and molecular level are…”
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