Search Results - "Tunn, Ruth"
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Incidence and outcomes of vasa praevia in the United Kingdom
Published in NIHR open research (2024)“…Vasa praevia is an obstetric condition in which the fetal vessels run through the membrane over the internal cervical os, unprotected by the placenta or…”
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An update to SPIRIT and CONSORT reporting guidelines to enhance transparency in randomized trials
Published in Nature Medicine (01-09-2022)“…Results from clinical trials can be deemed trustworthy only if they are properly conducted and their methods are fully reported. The SPIRIT and CONSORT…”
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Methods used to develop the SPIRIT 2024 and CONSORT 2024 Statements
Published in Journal of clinical epidemiology (01-05-2024)“…To describe, and explain the rationale for, the methods used and decisions made during development of the updated SPIRIT 2024 and CONSORT 2024 reporting…”
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4
TPC1 Has Two Variant Isoforms, and Their Removal Has Different Effects on Endo-Lysosomal Functions Compared to Loss of TPC2
Published in Molecular and cellular biology (01-11-2014)“…Organelle ion homeostasis within the endo-lysosomal system is critical for physiological functions. Two-pore channels (TPCs) are cation channels that reside in…”
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5
Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells
Published in The Journal of biological chemistry (28-08-2015)“…Pancreatic β cells are electrically excitable and respond to elevated glucose concentrations with bursts of Ca2+ action potentials due to the activation of…”
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6
Absence of Intracellular Ion Channels TPC1 and TPC2 Leads to Mature-Onset Obesity in Male Mice, Due to Impaired Lipid Availability for Thermogenesis in Brown Adipose Tissue
Published in Endocrinology (Philadelphia) (01-03-2015)“…Intracellular calcium-permeable channels have been implicated in thermogenic function of murine brown and brite/beige adipocytes, respectively transient…”
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Expression of two-pore channels in mammalian primary cells and tissues, and their role in adipose tissue formation and function
Published 01-01-2012“…Two-pore channels (TPCs, gene name Tpcn) have recently been identified as endolysosomal cation channels modulated by the potent calcium (Ca2+) releasing…”
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Dissertation