Search Results - "Tumor biology"

Progress in the treatment of advanced gastric cancer by Song, Zheyu, Wu, Yuanyu, Yang, Jiebing, Yang, Dingquan, Fang, Xuedong

“…Gastric cancer is one of the most common malignant tumors in the digestive system. Surgery is currently considered to be the only radical treatment. As…”
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Role of interleukin-6 in cancer progression and therapeutic resistance by Kumari, Neeraj, Dwarakanath, B. S., Das, Asmita, Bhatt, Anant Narayan

“…In the last several decades, the number of people dying from cancer-related deaths has not reduced significantly despite phenomenal advances in the…”
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Major apoptotic mechanisms and genes involved in apoptosis by Kiraz, Yağmur, Adan, Aysun, Kartal Yandim, Melis, Baran, Yusuf

“…As much as the cellular viability is important for the living organisms, the elimination of unnecessary or damaged cells has the opposite necessity for the…”
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Plasma long noncoding RNA protected by exosomes as a potential stable biomarker for gastric cancer by Li, Qier, Shao, Yongfu, Zhang, Xinjun, Zheng, Tuo, Miao, Min, Qin, Lijun, Wang, Bojun, Ye, Guoliang, Xiao, Bingxiu, Guo, Junming

“…Long intergenic non-protein-coding RNA 152 (LINC00152) is one of the long noncoding RNAs (lncRNAs) abnormally expressed in gastric cancer tissues. However, its…”
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Collagen as a double-edged sword in tumor progression by Fang, Min, Yuan, Jingping, Peng, Chunwei, Li, Yan

“…It has been recognized that cancer is not merely a disease of tumor cells, but a disease of imbalance, in which stromal cells and tumor microenvironment play…”
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MALAT1 promotes the proliferation and metastasis of osteosarcoma cells by activating the PI3K/Akt pathway by Dong, Yongqiang, Liang, Guojun, Yuan, Bo, Yang, Chaoqun, Gao, Rui, Zhou, Xuhui

“…Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), one of the first found cancer-associated long noncoding RNAs (lncRNAs), involves in the…”
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Molecular targets of curcumin for cancer therapy: an updated review by Kasi, Pandima Devi, Tamilselvam, Rajavel, Skalicka-Woźniak, Krystyna, Nabavi, Seyed Fazel, Daglia, Maria, Bishayee, Anupam, Pazoki-toroudi, Hamidreza, Nabavi, Seyed Mohammad

“…In recent years, natural edible products have been found to be important therapeutic agents for the treatment of chronic human diseases including cancer,…”
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The role of oxidative stress on breast cancer development and therapy by Hecht, Fabio, Pessoa, Carolina F., Gentile, Luciana B., Rosenthal, Doris, Carvalho, Denise P., Fortunato, Rodrigo S.

“…Reactive oxygen species (ROS) are produced by both enzymatic and non-enzymatic systems within eukaryotic cells and play important roles in cellular physiology…”
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Downregulated long noncoding RNA MEG3 is associated with poor prognosis and promotes cell proliferation in gastric cancer by Sun, Ming, Xia, Rui, Jin, Feiyan, Xu, Tongpeng, Liu, Zhijun, De, Wei, Liu, Xianghua

“…Long noncoding RNAs (lncRNAs) have emerged recently as major players in governing fundamental biological processes, and many of which are altered in expression…”
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LncRNAs: key players and novel insights into cervical cancer by Peng, Li, Yuan, Xiaoqing, Jiang, Binyuan, Tang, Zaili, Li, Guan-Cheng

“…Cervical cancer contributed the second highest number of deaths in female cancers, exceeded only by breast cancer, carrying high risks of morbidity and…”
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H19 promotes pancreatic cancer metastasis by derepressing let-7’s suppression on its target HMGA2-mediated EMT by Ma, Chenchao, Nong, Kate, Zhu, Hongda, Wang, Weiwei, Huang, Xinyu, Yuan, Zhou, Ai, Kaixing

“…The long noncoding RNA (lncRNA) H19 has been recently characterized as an oncogenic lncRNA in some tumors. However, the role of H19 in pancreatic ductal…”
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Exosomes derived from gastric cancer cells activate NF-κB pathway in macrophages to promote cancer progression by Wu, Lijun, Zhang, Xu, Zhang, Bin, Shi, Hui, Yuan, Xiao, Sun, Yaoxiang, Pan, Zhaoji, Qian, Hui, Xu, Wenrong

“…Exosomes are nano-sized membrane vesicles secreted by both normal and cancer cells. Emerging evidence indicates that cancer cells derived exosomes contribute…”
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Long noncoding RNA: an emerging paradigm of cancer research by Qiu, Man-Tang, Hu, Jing-Wen, Yin, Rong, Xu, Lin

“…Recent studies have demonstrated the importance of non-protein coding part of human genome in carcinogenesis and metastasis. Among numerous kinds of…”
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Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets by Hadler-Olsen, Elin, Winberg, Jan-Olof, Uhlin-Hansen, Lars

“…Biomarkers are used as tools in cancer diagnostics and in treatment stratification. In most cancers, there are increased levels of one or several members of…”
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The emerging role of targeting cancer metabolism for cancer therapy by Farhadi, Pegah, Yarani, Reza, Dokaneheifard, Sadat, Mansouri, Kamran

“…Glucose, as the main consuming nutrient of the body, faces different destinies in cancer cells. Glycolysis, oxidative phosphorylation, and pentose phosphate…”
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LncRNA HOTAIR promotes cisplatin resistance in gastric cancer by targeting miR-126 to activate the PI3K/AKT/MRP1 genes by Yan, Jin, Dang, Yini, Liu, Shiyu, Zhang, Yifeng, Zhang, Guoxin

“…Altered expression of long noncoding RNAs (lncRNAs) has shown to associate with human cancer development and progression and drug resistance. LncRNA HOX…”
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Upregulation of long non-coding RNA MALAT1 correlates with tumor progression and poor prognosis in clear cell renal cell carcinoma by Zhang, Hai-min, Yang, Feng-qiang, Chen, Shao-Jun, Che, Jianping, Zheng, Jun-hua

“…Long noncoding RNAs (lncRNAs) have been investigated as a new class of regulators of cellular processes, such as cell growth, apoptosis, and carcinogenesis…”
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C-Myc-activated long noncoding RNA CCAT1 promotes colon cancer cell proliferation and invasion by He, Xiaolu, Tan, Xueming, Wang, Xiang, Jin, Heiying, Liu, Li, Ma, Limei, Yu, Hong, Fan, Zhining

“…Recently, more and more evidence are rapidly accumulating that long noncoding RNAs (lncRNAs) are involved in human tumorigenesis and misregulated in many…”
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The M2 phenotype of tumor-associated macrophages in the stroma confers a poor prognosis in pancreatic cancer by Hu, Hai, Hang, Jun-Jie, Han, Ting, Zhuo, Meng, Jiao, Feng, Wang, Li-Wei

“…Macrophages play a critical role in the initiation and progression of various solid tumors. However, their prognostic significance in pancreatic ductal…”
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Association of well-characterized lung cancer lncRNA polymorphisms with lung cancer susceptibility and platinum-based chemotherapy response by Gong, Wei-Jing, Yin, Ji-Ye, Li, Xiang-Ping, Fang, Chao, Xiao, Di, Zhang, Wei, Zhou, Hong-Hao, Li, Xi, Liu, Zhao-Qian

“…Long non-coding RNAs (lncRNAs) play important roles in carcinogenesis and drug efficacy. Platinum-based chemotherapy is first-line treatment for lung cancer…”
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