Search Results - "Tumiati, Laura"
-
1
Increases in Serum Autoantibodies After Left Ventricular Assist Device Implantation
Published in Journal of cardiac failure (01-04-2019)“…Left ventricular assist devices (LVADs) can serve as a bridge to transplant or destination therapy for patients with advanced heart failure. Implantation of…”
Get full text
Journal Article -
2
10-Year Experience with HLA-G in Heart Transplantation
Published in Human immunology (01-08-2018)“…The Human Leukocyte Antigen-G (HLA-G) is a MHC-class Ib molecule with robust immunomodulatory properties; in transplant, it inhibits cytotoxic activity of…”
Get full text
Journal Article -
3
Recipient hypertonic saline infusion prevents cardiac allograft dysfunction
Published in The Journal of thoracic and cardiovascular surgery (01-02-2019)“…Hypertonic saline (HTS) has potent immune and vascular effects. We assessed recipient pretreatment with HTS on allograft function in a porcine model of heart…”
Get full text
Journal Article -
4
Generation of Antigen Microarrays to Screen for Autoantibodies in Heart Failure and Heart Transplantation
Published in PloS one (11-03-2016)“…Autoantibodies directed against endogenous proteins including contractile proteins and endothelial antigens are frequently detected in patients with heart…”
Get full text
Journal Article -
5
Increased cyclic guanosine monophosphate levels and continuous-flow left-ventricular assist devices: Implications for gastrointestinal bleeding
Published in The Journal of thoracic and cardiovascular surgery (01-01-2016)“…Abstract Objectives We examine the hypothesis that cyclic guanosine monophosphate (cGMP) levels are elevated in recipients of continuous-flow left ventricular…”
Get full text
Journal Article -
6
Progressive Aortic Dilation Is Regulated by miR-17–Associated miRNAs
Published in Journal of the American College of Cardiology (28-06-2016)“…Abstract Background Patients with a bicuspid aortic valve (BAV) are at increased risk for progressive aortic dilation associated with extracellular matrix…”
Get full text
Journal Article -
7
Effects of everolimus and HLA‐G on cellular proliferation and neutrophil adhesion in an in vitro model of cardiac allograft vasculopathy
Published in American journal of transplantation (01-12-2018)“…Human leukocyte antigen‐G (HLA‐G) expression is modulated by immunosuppressant use and is associated with lower incidence of graft rejection and cardiac…”
Get full text
Journal Article -
8
New Developments in HLA-G in Cardiac Transplantation
Published in Human immunology (01-09-2016)“…Abstract Human Leukocyte Antigen-G (HLA-G) is a non-classical class 1b protein, whose gene is located on chromosome 6 (6p21.31). HLA-G inhibits the immune…”
Get full text
Journal Article -
9
Longitudinal Assessment of Inflammation in Recipients of Continuous-Flow Left Ventricular Assist Devices
Published in Canadian journal of cardiology (01-03-2015)“…Abstract Background The long-term effects of continuous-flow left ventricular assist device (CF-LVAD) support on trends of inflammatory markers over time are…”
Get full text
Journal Article -
10
Elevated endothelin-1 levels impair nitric oxide homeostasis through a PKC-dependent pathway
Published in Circulation (New York, N.Y.) (04-07-2006)“…Endothelin-1 (ET-1) plays an important role in the maintenance of vascular tone and pathological states such as ischemia/reperfusion (I/R) injury, coronary…”
Get full text
Conference Proceeding Journal Article -
11
Improved heart function with myogenesis and angiogenesis after autologous porcine bone marrow stromal cell transplantation
Published in The Journal of thoracic and cardiovascular surgery (01-06-2002)“…Objective: The study evaluated the utility of transplanting bone marrow stromal cells in a porcine myocardial infarction model. Methods: A myocardial…”
Get full text
Journal Article -
12
-
13
Markers of Inflammation in Recipients of Continuous-Flow Left Ventricular Assist Devices
Published in ASAIO journal (1992) (01-11-2014)“…Although the newer continuous-flow left ventricular assist devices (CF-LVADs) provide clinical advantages over the pulsatile pumps, the effects of low…”
Get full text
Journal Article -
14
Epidermal Growth Factor-Like Domain 7 Suppresses Intercellular Adhesion Molecule 1 Expression in Response to Hypoxia/Reoxygenation Injury in Human Coronary Artery Endothelial Cells
Published in Circulation (New York, N.Y.) (14-09-2010)“…Epidermal growth factor-like domain 7 (Egfl7) is a chemoattractant for endothelial cells, and its expression is restricted to endothelial cells…”
Get full text
Journal Article -
15
Role of endothelin-1 and nitric oxide bioavailability in transplant-related vascular injury : Comparative effects of rapamycin and cyclosporine
Published in Circulation (New York, N.Y.) (04-07-2006)“…Cyclosporine (CyA) is associated with many side effects, including endothelial dysfunction and transplant vasculopathy (TxV). We previously demonstrated that…”
Get full text
Conference Proceeding Journal Article -
16
Progesterone induces human leukocyte antigen-g expression in vascular endothelial and smooth muscle cells
Published in Circulation (New York, N.Y.) (30-09-2008)“…Human leukocyte antigen-G (HLA-G) expression in heart transplant patients has been negatively associated with acute cellular rejection and cardiac allograft…”
Get full text
Journal Article -
17
Epidermal Growth Factor―Like Domain 7 Is a Novel Inhibitor of Neutrophil Adhesion to Coronary Artery Endothelial Cells Injured by Calcineurin Inhibition
Published in Circulation (New York, N.Y.) (13-09-2011)“…We investigated the effect of epidermal growth factor-like domain 7 (Egfl7) on nuclear factor-κB activation, intercellular adhesion molecule-1 expression, and…”
Get full text
Conference Proceeding Journal Article -
18
Endothelin-1 antagonism and nitric oxide augmentation prevents cyclosporine-induced vasomotor impairment
Published in The Journal of heart and lung transplantation (2011)“…Background We previously demonstrated that cyclosporine (CyA) impairs endothelial function as a result of alterations in nitric oxide (NO) and endothelin-1…”
Get full text
Journal Article -
19
Donor Pretreatment With Hypertonic Saline Attenuates Primary Allograft Dysfunction: A Pilot Study in a Porcine Model
Published in Circulation (New York, N.Y.) (15-09-2009)“…Hypertonic saline (HTS) has been previously demonstrated to have immune modulatory and vascular protective effects. We assessed the effect of donor…”
Get full text
Conference Proceeding Journal Article -
20
Tacrolimus preserves vasomotor function and maintains vascular homeostasis
Published in The Journal of heart and lung transplantation (01-05-2011)“…Background Post-transplant immunosuppression is associated with endothelial dysfunction that may lead to vasculopathy. We have previously demonstrated that…”
Get full text
Journal Article