Search Results - "Tumiati, L C"

Insulin stimulates pyruvate dehydrogenase and protects human ventricular cardiomyocytes from simulated ischemia by Rao, Vivek, Merante, Frank, Weisel, Richard D., Shirai, Toshizumi, Ikonomidis, John S., Cohen, Gideon, Tumiati, Laura C., Shiono, Noritsugu, Li, Ren-Ke, Mickle, Donald A., Robinson, Brian H.

“…Impaired myocardial metabolism after cardioplegic arrest results in persistent anaerobic lactate production. Insulin may protect the heart from ischemia and…”
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Preconditioning human cardiomyocytes and endothelial cells by Shirai, Toshizumi, Rao, Vivek, Weisel, Richard D., Ikonomidis, John S., Li, Ren-Ke, Tumiati, Laura C., Merante, Frank, Mickle, Donald A.

“…Background: The effects of simulated “ischemia” and “reperfusion” were evaluated in cell cultures of human ventricular cardiomyocytes and human saphenous vein…”
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Effect of oxygen tension and cardiovascular operations on the myocardial antioxidant enzyme activities in patients with tetralogy of Fallot and aorta-coronary bypass by Teoh, K H, Mickle, D A, Weisel, R D, Li, R K, Tumiati, L C, Coles, J G, Williams, W G

“…Since the chronically cyanotic myocardium appears to be more susceptible to reperfusion injury after cardiac operations than the noncyanotic myocardium, we…”
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Human pediatric and adult ventricular cardiomyocytes in culture: assessment of phenotypic changes with passaging by Li, Ren-Ke, Mickle, Donald A.G., Weisel, Richard D., Carson, Susan, Omar, Sue A., Tumiati, Laura C., Wilson, Gregory J., Williams, William G.

“…Objectives: The purpose of this study was to assess morphologically and biochemically the phenotypic changes which occur in vitro with passaging of human…”
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Myocardial free-radical injury after cardioplegia by Weisel, R D, Mickle, D A, Finkle, C D, Tumiati, L C, Madonik, M M, Ivanov, J, Burton, G W, Ingold, K U

“…Although cold blood cardioplegia provides excellent myocardial protection for elective coronary bypass surgery, myocardial metabolic recovery is delayed…”
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Which techniques of cardioplegia prevent ischemia? by Yau, Terrence M., Ikonomidis, John S., Weisel, Richard D., Mickle, Donald A.G., Hayashida, Nobuhiko, Ivanov, Joan, Carson, Susan, Mohabeer, Molly K., Tumiati, Laura C.

“…One hundred seven patients undergoing coronary artery bypass grafting were randomized to receive warm antegrade (n = 21), warm retrograde (n = 22), cold…”
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Prolonged hypothermic cardiac storage for transplantation. The effects on myocardial metabolism and mitochondrial function by See, Y P, Weisel, R D, Mickle, D A, Teoh, K H, Wilson, G J, Tumiati, L C, Mohabeer, M K, Madonik, M M, Axford-Gatley, R A, Salter, D R

“…Cardiac storage for transplantation is currently limited to 6 hours. To better understand the metabolic changes that occur during hypothermic (4 degrees C)…”
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Effect of oxygen tension on the anti-oxidant enzyme activities of tetralogy of Fallot ventricular myocytes by Li, R K, Mickle, D A, Weisel, R D, Tumiati, L C, Jackowski, G, Wu, T W, Williams, W G

“…Since the chronically cyanotic tetralogy of Fallot (TOF) myocardium is more sensitive to reperfusion injury after cardiac surgery than the adult myocardium, we…”
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Adequate distribution of warm cardioplegic solution by Hayashida, Nobuhiko, Ikonomidis, John S., Weisel, Richard D., Shirai, Toshizumi, Ivanov, Joan, Carson, Susan, Mohabeer, Molly K., Tumiati, Laura C., Mickle, Donald A.G.

“…Seventy-five patients undergoing coronary artery bypass grafting were randomized to receive warm antegrade ( N = 25), warm retrograde ( N = 25), or a…”
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Prolonged hypothermic cardiac storage with University of Wisconsin solution. An assessment with human cell cultures by Fremes, S E, Li, R K, Weisel, R D, Mickle, D A, Tumiati, L C

“…Hypothermic storage of cardiac allografts is routinely used for transplantation but is associated with an increased mortality when ischemic times are greater…”
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Preconditioning human ventricular cardiomyocytes with brief periods of simulated ischaemia by Ikonomidis, J S, Tumiati, L C, Weisel, R D, Mickle, D A, Li, R K

“…The aim was to test for "ischaemic" preconditioning in monolayer cultures of quiescent human ventricular cardiomyocytes. Stabilised cardiomyocytes (n = 8…”
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Cardiac storage with University of Wisconsin solution and a nucleoside-transport blocker by Fremes, Stephen E., Furukawa, Robert D., Zhang, Ji, Li, Ren-Ke, Tumiati, Laura C., Weisel, Richard D., Mickle, Donald A.G.

“…Findings from previous investigations conducted at this institution and others have suggested that University of Wisconsin solution (UWS) is preferable for the…”
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Delayed Myocardial Metabolic Recovery After Blood Cardioplegia by Weisel, Richard D., Mickle, Donald A.G., Finkle, Carolyn D., Tumiati, Laura C., Madonik, M. Mindy, Ivanov, Joan

“…Previous studies have demonstrated that both myocardial metabolism and ventricular function were depressed after blood cardioplegic arrest for elective…”
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Comparison of two experimental models for assessment of cardiac preservation by Fremes, Stephen E., Furukawa, Robert D., Li, Ren-Ke, Weisel, Richard D., Mickle, Donald A.G., Tumiati, Laura C.

“…Previous studies from this institution using human cell cultures have suggested that University of Wisconsin solution is preferred for prolonged hypothermic…”
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The characterization and purification of a human transcription factor modulating the glutathione peroxidase gene in response to oxygen tension by Merante, Frank, Altamentova, Svetlana M, Mickle, Donald A G, Weisel, Richard D, Thatcher, Bradley J, Martin, Brian M, Marshall, John G, Tumiati, Laura C, Cowan, Douglas B, Li, Ren-Ke

“…An oxygen responsive transcription factor regulating human glutathione peroxidase gene (GPx) through two oxygen responsive elements (ORE I and ORE2) has been…”
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The limits of cardiac preservation with University of Wisconsin solution by Fremes, Stephen E., Li, Ren-Ke, Weisel, Richard D., Mickle, Donald A.G., Furukawa, Robert D., Tumiati, Laura C.

“…Previous studies from this institution have suggested that University of Wisconsin solution is preferred for prolonged cardiac storage and preserves…”
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Prolonged preservation with University of Wisconsin Solution by Fremes, S E, Furukawa, R D, Li, R K, Weisel, R D, Mickle, D A, Tumiati, L C

“…Previous studies from this institution using human cell cultures have suggested that University of Wisconsin Solution may be preferred for prolonged cardiac…”
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The optimal cardioplegic temperature by Hayashida, Nobuhiko, Ikonomidis, John S., Weisel, Richard D., Shirai, Toshizumi, Ivanov, Joan, Carson, Susan M., Mohabeer, Molly K., Tumiati, Laura C., Mickle, Donald A.G.

“…Seventy-two patients undergoing coronary artery bypass grafting were randomized to receive cold (8 °C) antegrade or retrograde, tepid (29 °C) antegrade or…”
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Optimal myocardial preconditioning in a human model of ischemia and reperfusion by Cohen, G, Shirai, T, Weisel, R D, Rao, V, Merante, F, Tumiati, L C, Mohabeer, M K, Borger, M A, Li, R K, Mickle, D A

“…Adenosine (ADE) may mediate the protective effects of preconditioning (PC). However, human data are lacking, and the optimal method of ADE administration and…”
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Tepid antegrade and retrograde cardioplegia by Hayashida, Nobuhiko, Weisel, Richard D., Shirai, Toshizumi, Ikonomidis, John S., Ivanov, Joan, Carson, Susan M., Mohabeer, Molly K., Tumiati, Laura C., Mickle, Donald A.G.

“…To determine the optimal temperature for the combination of antegrade and retrograde cardioplegia, 42 patients undergoing coronary artery bypass grafting were…”
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