Search Results - "Tumedei, Maria"
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1
Are fine‐needle aspiration biopsy‐derived cell blocks a useful surrogate for tissue samples in breast cancer?
Published in Histopathology (01-11-2018)“…Aims The diagnosis of breast cancer (BC) is based on clinical examination in combination with imaging, and confirmed by pathological assessment of core needle…”
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2
Three-dimensional collagen-based scaffold model to study the microenvironment and drug-resistance mechanisms of oropharyngeal squamous cell carcinomas
Published in Cancer biology & medicine (01-05-2021)“…Squamous cell carcinoma (SCC) represents the most common histotype of all head and neck malignancies and includes oropharyngeal squamous cell carcinoma (OSCC),…”
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3
PSMA expression: a potential ally for the pathologist in prostate cancer diagnosis
Published in Scientific reports (09-03-2018)“…Prostate cancer (PCa) patients are risk-stratified on the basis of clinical stage and PSA level at diagnosis and the Gleason Score (GS) in prostate biopsy…”
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4
Pancreatic Cancer and Cellular Senescence: Tumor Microenvironment under the Spotlight
Published in International journal of molecular sciences (27-12-2021)“…Pancreatic ductal adenocarcinoma (PDAC) has one of the most dismal prognoses of all cancers due to its late manifestation and resistance to current therapies…”
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5
Ki67 and PR in Patients Treated with CDK4/6 Inhibitors: A Real-World Experience
Published in Diagnostics (Basel) (08-08-2020)“…CDK4/6 inhibitors (CDK4/6i) are recommended in patients with estrogen receptor (ER)-positive, HER2-negative advanced breast cancer (ABC). Up to now, no…”
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6
Role of Telomerase in Cervical Lesions as Prognostic Marker: A Comparison Between Immunohistochemistry and Fluorescence In Situ Hybridization
Published in Journal of lower genital tract disease (01-01-2017)“…Amplification of human telomerase is known to be associated with cervical tumorigenesis, although its role in tumor progression of cervical lesions is still…”
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7
Early Gastric Cancer: identification of molecular markers able to distinguish submucosa-penetrating lesions with different prognosis
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-03-2021)“…Background Early Gastric Cancer (EGC) reaches 25% of the gastric cancers surgically treated in some areas of Northeastern Italy and is usually characterized by…”
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8
Data Science for Health Image Alignment: A User-Friendly Open-Source ImageJ/Fiji Plugin for Aligning Multimodality/Immunohistochemistry/Immunofluorescence 2D Microscopy Images
Published in Sensors (Basel, Switzerland) (01-01-2024)“…Most of the time, the deep analysis of a biological sample requires the acquisition of images at different time points, using different modalities and/or…”
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9
Androgen receptor in breast cancer: The “5W” questions
Published in Frontiers in endocrinology (Lausanne) (30-08-2022)“…Androgen receptor (AR) is expressed in 60-70% of breast cancers (BCs) and the availability of anti-AR compounds, currently used for treating prostate cancer,…”
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10
Promoter methylation of tumor suppressor genes in pre-neoplastic lesions; potential marker of disease recurrence
Published in Journal of experimental & clinical cancer research (05-08-2014)“…Epigenetic alterations of specific genes have been reported to be related to colorectal cancer (CRC) transformation and would also appear to be involved in the…”
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11
Easily detectable cytomorphological features to evaluate during ROSE for rapid lung cancer diagnosis: from cytology to histology
Published in Oncotarget (14-02-2017)“…In lung cancer patients, the only available diagnostic material often comes from biopsy or from cytological samples obtained by fine needle aspiration (FNA)…”
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12
Spotlight on PSMA as a new theranostic biomarker for bladder cancer
Published in Scientific reports (07-05-2021)“…Bladder cancer (BCa) patients are diagnosed by cytology and cystoscopy. However, these diagnostic tests bear some limitations. We sought for reliable…”
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13
Follicular Lymphoma Microenvironment Traits Associated with Event-Free Survival
Published in International journal of molecular sciences (01-06-2023)“…The majority of patients with Follicular Lymphoma (FL) experience subsequent phases of remission and relapse, making the disease "virtually" incurable. To…”
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14
ACE2 and TMPRSS2 Potential Involvement in Genetic Susceptibility to SARS-COV-2 in Cancer Patients
Published in Cell transplantation (01-01-2020)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. One open question is whether genetics could influence the severity…”
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15
Androgen receptor in advanced breast cancer: is it useful to predict the efficacy of anti-estrogen therapy?
Published in BMC cancer (27-03-2018)“…Androgen receptor (AR) is widely expressed in breast cancer (BC) but its role in estrogen receptor (ER)-positive tumors is still controversial. The AR/ER ratio…”
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16
Tumor resident microbiota and response to therapies: An insight on tissue bacterial microbiota
Published in Frontiers in cell and developmental biology (04-01-2023)“…The role of the intestinal microbiota in the promotion, progression, and response to therapies is gaining importance, but recent studies confirm the presence…”
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17
Tumor-Infiltrating Lymphocytes (TILs) and Risk of a Second Breast Event After a Ductal Carcinoma in situ
Published in Frontiers in oncology (19-08-2020)“…Women with a diagnosis of ductal carcinoma in situ (DCIS) have a high risk of developing a second breast event (SBE). The immune system might play a role in…”
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Spotlight on Ki67 as a prognostic marker in early breast cancer: all that glitters may not be gold
Published in Diagnostic pathology (11-09-2020)“…Kang and colleagues evaluated on a case series of 1848 breast cancer (BC) patients operated for a first primary ER positive HER2 negative BC if Ki67 expression…”
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19
Cell-Free DNA Variant Sequencing Using CTC-Depleted Blood for Comprehensive Liquid Biopsy Testing in Metastatic Breast Cancer
Published in Cell transplantation (01-01-2020)“…Keup and colleagues provide liquid biopsy preliminary results by sequencing variants in circulating tumor cells (CTCs) and cell-free deoxyribonucleic acid…”
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20
Why the complications of COVID-19 patients differ in elderly and young cancer patients
Published in Translational oncology (01-12-2022)“…Zhang et al. reported the impact of different risk factors and comorbidities in COVID-19 lethality. The authors observed that the odds of dying by COVID-19 in…”
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