Search Results - "Tulu, U Serdar"
-
1
Visualizing Intracellular Organelle and Cytoskeletal Interactions at Nanoscale Resolution on Millisecond Timescales
Published in Cell (15-11-2018)“…In eukaryotic cells, organelles and the cytoskeleton undergo highly dynamic yet organized interactions capable of orchestrating complex cellular functions…”
Get full text
Journal Article -
2
Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions
Published in Science (American Association for the Advancement of Science) (09-03-2012)“…Apical constriction changes cell shapes, driving critical morphogenetic events, including gastrulation in diverse organisms and neural tube closure in…”
Get full text
Journal Article -
3
An osteopenic/osteoporotic phenotype delays alveolar bone repair
Published in Bone (New York, N.Y.) (01-07-2018)“…Aging is associated with a function decline in tissue homeostasis and tissue repair. Aging is also associated with an increased incidence in osteopenia and…”
Get full text
Journal Article -
4
Superresolution microscopy reveals actomyosin dynamics in medioapical arrays
Published in Molecular biology of the cell (15-09-2022)“…Superresolution microscopy produced images of individual actin and myosin filaments and their three-dimensional distribution in medioapical arrays of cells in…”
Get full text
Journal Article -
5
Kinetochore Dynein Is Required for Chromosome Motion and Congression Independent of the Spindle Checkpoint
Published in Current biology (05-06-2007)“…During mitosis, the motor molecule cytoplasmic dynein plays key direct and indirect roles in organizing microtubules (MTs) into a functional spindle. At this…”
Get full text
Journal Article -
6
Molecular Requirements for Kinetochore-Associated Microtubule Formation in Mammalian Cells
Published in Current biology (07-03-2006)“…In centrosome-containing cells, microtubules nucleated at centrosomes are thought to play a major role in spindle assembly [1]. In addition, microtubule…”
Get full text
Journal Article -
7
Centrosome Maturation: Measurement of Microtubule Nucleation throughout the Cell Cycle by Using GFP-Tagged EB1
Published in Proceedings of the National Academy of Sciences - PNAS (10-02-2004)“…Understanding how cells regulate microtubule nucleation during the cell cycle has been limited by the inability to directly observe nucleation from the…”
Get full text
Journal Article -
8
Reorganization of the Microtubule Array in Prophase/Prometaphase Requires Cytoplasmic Dynein-Dependent Microtubule Transport
Published in The Journal of cell biology (16-09-2002)“…When mammalian somatic cells enter mitosis, a fundamental reorganization of the Mt cytoskeleton occurs that is characterized by the loss of the extensive…”
Get full text
Journal Article -
9
Quantification of microtubule nucleation, growth and dynamics in wound-edge cells
Published in Journal of cell science (15-09-2005)“…Mammalian cells develop a polarized morphology and migrate directionally into a wound in a monolayer culture. To understand how microtubules contribute to…”
Get full text
Journal Article -
10
Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution
Published in Science (American Association for the Advancement of Science) (24-10-2014)“…Although fluorescence microscopy provides a crucial window into the physiology of living specimens, many biological processes are too fragile, are too small,…”
Get full text
Journal Article -
11
Human Tendon–Derived Collagen Hydrogel Significantly Improves Biomechanical Properties of the Tendon-Bone Interface in a Chronic Rotator Cuff Injury Model
Published in The Journal of hand surgery (American ed.) (01-10-2019)“…Poor healing of the tendon-bone interface (TBI) after rotator cuff (RTC) tears leads to high rates of recurrent tear following repair. Previously, we…”
Get full text
Journal Article -
12
Complete canthi removal reveals that forces from the amnioserosa alone are sufficient to drive dorsal closure in Drosophila
Published in Molecular biology of the cell (05-11-2014)“…Drosophila's dorsal closure provides an excellent model system with which to analyze biomechanical processes during morphogenesis. During native closure, the…”
Get full text
Journal Article -
13
A Novel Osteotomy Preparation Technique to Preserve Implant Site Viability and Enhance Osteogenesis
Published in Journal of clinical medicine (01-02-2019)“…The preservation of bone viability at an osteotomy site is a critical variable for subsequent implant osseointegration. Recent biomechanical studies evaluating…”
Get full text
Journal Article -
14
Photoactivatable Green Fluorescent Protein-Tubulin
Published in Methods in Cell Biology (2010)“…Direct observations of live cells expressing fluorescently tagged tubulin have led to important advances in our understanding of mitosis. A limitation of this…”
Get full text
Book Chapter Journal Article -
15
Stable expression of fluorescently tagged proteins for studies of mitosis in mammalian cells
Published in Nature methods (01-12-2005)Get full text
Journal Article -
16
Actomyosin purse strings: Renewable resources that make morphogenesis robust and resilient
Published in HFSP Journal (01-08-2008)“…Dorsal closure in Drosophila is a model system for cell sheet morphogenesis and wound healing. During closure two sheets of lateral epidermis move dorsally to…”
Get full text
Journal Article -
17
Super-resolution microscopy reveals actomyosin dynamics in medioapical arrays
Published in Molecular biology of the cell (11-05-2022)“…Arrays of actin filaments (F-actin) near the apical surface of epithelial cells (medioapical arrays) contribute to apical constriction and morphogenesis…”
Get full text
Journal Article -
18
Triggering a Cell Shape Change by Exploiting Pre-Existing Actomyosin Contractions
Published in Science (American Association for the Advancement of Science) (09-02-2012)“…Apical constriction changes cell shapes, driving critical morphogenetic events including gastrulation in diverse organisms and neural tube closure in…”
Get full text
Journal Article