Search Results - "Tully, Ellen"

A high-throughput and open-source platform for embryo phenomics by Tills, Oliver, Spicer, John I, Grimmer, Andrew, Marini, Simone, Jie, Vun Wen, Tully, Ellen, Rundle, Simon D

“…Phenomics has the potential to facilitate significant advances in biology but requires the development of high-throughput technologies capable of generating…”
Get full text

Inhibiting Fatty Acid Synthase for Chemoprevention of Chemically Induced Lung Tumors by ORITA, Hajime, COULTER, Jonathan, TULLY, Ellen, KUHAJDA, Francis P, GABRIELSON, Edward

“…Purpose: Fatty acid synthase (FAS) is overexpressed in lung cancer, and we have investigated the potential use of FAS inhibitors for chemoprevention of lung…”
Get full text

Increased Expression of Mitotic Checkpoint Genes in Breast Cancer Cells with Chromosomal Instability by BIBO YUAN, YI XU, WOO, Ju-Hyung, YUNYUE WANG, YOUNG KYUNG BAE, YOON, Dae-Sung, WERSTO, Robert P, TULLY, Ellen, WILSBACH, Kathleen, GABRIELSON, Edward

“…Purpose: Most breast cancers have chromosomal instability that seems related to defective mitotic spindle checkpoints. Because the molecular basis of this…”
Get full text

Selective Inhibition of Fatty Acid Synthase for Lung Cancer Treatment by ORITA, Hajime, COULTER, Jonathan, LEMMON, Colleen, TULLY, Ellen, VADLAMUDI, Aravinda, MEDGHALCHI, Susan M, KUHAJDA, Francis P, GABRIELSON, Edward

“…Purpose: Fatty acid synthase (FAS) is overexpressed in many human cancers and is considered to be a promising target for therapy. However, in vitro use of…”
Get full text

Coix seed extract, A commonly used treatment for cancer in china, inhibits NFκB and protein kinase C signaling by Woo, Ju-Hyung, Dapeng, Li, Orita, Hajime, Coulter, Jonathan, Tully, Ellen, Kwon, Taeg Kyu, Xu, Shi, Gabrielson, Edward

“…A pharmaceutical grade extract of Coix lachryma-jobi seeds is currently the most commonly used treatment for cancer in China. Although clinical data supports…”
Get full text

Noninvasive Monitoring of Allogeneic Stem Cell Delivery with Dual-Modality Imaging-Visible Microcapsules in a Rabbit Model of Peripheral Arterial Disease by Wacker, Frank, Bulte, Jeff W. M., Kraitchman, Dara L., Ehtiati, Tina, Solaiyappan, Meiyappan, Shea, Steven M., Tully, Ellen, Xie, Yibin, Kedziorek, Dorota A., Weiss, Clifford R., Fu, Yingli, Gabrielson, Kathleen L.

“…Stem cell therapies, although promising for treating peripheral arterial disease (PAD), often suffer from low engraftment rates and the inability to confirm…”
Get full text

High levels of fatty acid synthase expression in esophageal cancers represent a potential target for therapy by Orita, Hajime, Coulter, Jonathan, Tully, Ellen, Abe, Masaaki, Montgomery, Elizabeth, Alvarez, Hector, Sato, Koichi, Hino, Okio, Kajiyama, Yoshiaki, Tsurumaru, Masahiko, Gabrielson, Edward

“…Fatty acid synthase (FAS) is overexpressed in many human cancers and is considered to be a promising target for therapy. To investigate the expression of this…”
Get full text

Heterogeneous expression of PD-L1 in pulmonary squamous cell carcinoma and adenocarcinoma: implications for assessment by small biopsy by Gniadek, Thomas J, Li, Qing Kay, Tully, Ellen, Chatterjee, Samit, Nimmagadda, Sridhar, Gabrielson, Edward

“…Predicting response to checkpoint blockade therapy for lung cancer has largely focused on measuring programmed death-ligand 1 (PD-L1) expression on tumor…”
Get full text

Biguanide drugs enhance cytotoxic effects of cisplatin by depleting aspartate and NAD+ in sensitive cancer cells by Tully, Ellen, Bharti, Santosh, Woo, Juhyung, Bhujwalla, Zaver, Gabrielson, Edward

“…Biguanide drugs (metformin and phenformin) have drawn interest for potential cancer treatments, and laboratory studies show that some cancer cells are…”
Get full text

Nrf2 signaling and autophagy are complementary in protecting breast cancer cells during glucose deprivation by Walker, Alyssa, Singh, Anju, Tully, Ellen, Woo, Juhyung, Le, Anne, Nguyen, Tu, Biswal, Shyam, Sharma, Dipali, Gabrielson, Edward

“…Autophagy can serve as a mechanism for survival of cells during nutrient deprivation by recycling cellular macromolecules and organelles transiently to provide…”
Get full text

Peptide-based PET quantifies target engagement of PD-L1 therapeutics by Kumar, Dhiraj, Lisok, Ala, Dahmane, Elyes, McCoy, Matthew, Shelake, Sagar, Chatterjee, Samit, Allaj, Viola, Sysa-Shah, Polina, Wharram, Bryan, Lesniak, Wojciech G, Tully, Ellen, Gabrielson, Edward, Jaffee, Elizabeth M, Poirier, John T, Rudin, Charles M, Gobburu, Jogarao Vs, Pomper, Martin G, Nimmagadda, Sridhar

“…Immune checkpoint therapies have shown tremendous promise in cancer therapy. However, tools to assess their target engagement, and hence the ability to predict…”
Get full text

Temozolomide Sensitizes ARID1A-Mutated Cancers to PARP Inhibitors by Yu, Zheng-Cheng, Li, Tianhe, Tully, Ellen, Huang, Peng, Chen, Chih-Ning, Oberdoerffer, Philipp, Gaillard, Stephanie, Shih, Ie-Ming, Wang, Tian-Li

“…ARID1A is a subunit of SWI/SNF chromatin remodeling complexes and is mutated in many types of human cancers, especially those derived from endometrial…”
Get full text

Prognostic Impact of Phosphorylated Discoidin Domain Receptor-1 in Esophageal Cancer by Sugimoto, Kiichi, Ito, Tomoaki, Woo, Juhyung, Tully, Ellen, Sato, Koichi, Orita, Hajime, Brock, Malcolm V., Gabrielson, Edward

“…Esophageal squamous cell carcinoma (ESCC) is common in East Asia and also is often deadly. We sought to determine whether measuring the discoidin domain…”
Get full text

LabEmbryoCam: An opensource phenotyping system for developing aquatic animals by Ibbini, Ziad, Bruning, Maria, Allili, Sakina, Holmes, Luke A, Tully, Ellen, McCoy, Jamie, Larsen, Benjamin, Wilson, Tony, Ludford, Guy, Barrett-Kelly, Jack, Spicer, John I., Tills, Oliver

Get full text

Abstract 5928: Discoidin domain receptor-1 (DDR1) is an independent prognostic marker of poor prognosis in esophageal squamous cell carcinoma by Sugimoto, Kiichi, Ito, Tomoaki, Orita, Hajime, Sato, Koichi, Sakamoto, Kazuhiro, Sakurada, Mutsumi, Kushida, Tomoyuki, Maekawa, Hiroshi, Tully, Ellen, Woo, Juhyung, Gabrielson, Edward

“…Abstract Introduction: Esophageal squamous cell carcinoma (ESCC), which is the most common type of esophageal cancer, is one of the most common cancers in…”
Get full text

Nuclear Factor-κB (NF-κB) Mediates a Protective Response in Cancer Cells Treated with Inhibitors of Fatty Acid Synthase by Lemmon, Colleen R.M., Woo, Ju-Hyung, Tully, Ellen, Wilsbach, Kathleen, Gabrielson, Edward

“…The efficacy of drugs used to treat cancer can be significantly attenuated by adaptive responses of neoplastic cells to drug-induced stress. To determine how…”
Get full text

Abstract 5457: High levels of fatty acid synthase expression in esophageal cancers represent a potential target for therapy by Orita, Hajime, Coulter, Jonathan, Tully, Ellen, Montgomery, Elizabeth, Abe, Masaaki, Maekawa, Hiroshi, Sato, Kouichi, Tsurumaru, Masahiko, Hino, Okio, Gabrielson, Edward

“…Abstract Fatty acid synthase (FAS) is overexpressed in many human cancers and is considered to be a promising target for therapy. To investigate the expression…”
Get full text

Nuclear factor-kappaB (NF-kappaB) mediates a protective response in cancer cells treated with inhibitors of fatty acid synthase by Lemmon, Colleen R M, Woo, Ju-Hyung, Tully, Ellen, Wilsbach, Kathleen, Gabrielson, Edward

“…The efficacy of drugs used to treat cancer can be significantly attenuated by adaptive responses of neoplastic cells to drug-induced stress. To determine how…”
Get full text

Induction of spermidine/spermine N 1-acetyltransferase in breast cancer tissues treated with the polyamine analogue N 1,N 11-diethylnorspermine by Gabrielson, Edward, Tully, Ellen, Hacker, Amy, Pegg, Anthony E., Davidson, Nancy E., Casero, Robert A.

Get full text

Induction of spermidine/spermine N1-acetyltransferase in breast cancer tissues treated with the polyamine analogue N1, N11-diethyinorspermine by GABRIELSON, Edward, TULLY, Ellen, HACKER, Amy, PEGG, Anthony E, DAVIDSON, Nancy E, CASERO, Robert A

Get full text