Search Results - "Tullman, Jennifer"

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  1. 1

    Recovery of an HMWP/hmwBP (pUL48/pUL47) complex from virions of human cytomegalovirus: subunit interactions, oligomer composition, and deubiquitylase activity by Tullman, Jennifer A, Harmon, Mary-Elizabeth, Delannoy, Michael, Gibson, Wade

    Published in Journal of virology (01-08-2014)
    “…We report that the human cytomegalovirus (HCMV) high-molecular-weight tegument protein (HMWP, pUL48; 253 kDa) and the HMWP-binding protein (hmwBP, pUL47; 110…”
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    Journal Article
  2. 2

    Strategies for Development of a Next-Generation Protein Sequencing Platform by Callahan, Nicholas, Tullman, Jennifer, Kelman, Zvi, Marino, John

    “…Proteomic analysis can be a critical bottleneck in cellular characterization. The current paradigm relies primarily on mass spectrometry of peptides and…”
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    Journal Article
  3. 3

    A single amino acid substitution alters ClpS2 binding specificity by Bergonzo, Christina, Dharmadhikari, Kunal, Samuels, Emily, Christensen, Makenzie, Tullman, Jennifer

    “…ClpS2 is a small protein under development as a probe for selectively recognizing N‐terminal amino acids of N‐degron peptide fragments. To understand the…”
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    Journal Article
  4. 4

    A ClpS-based N-terminal amino acid binding reagent with improved thermostability and selectivity by Tullman, Jennifer, Christensen, Makenzie, Kelman, Zvi, Marino, John P.

    Published in Biochemical engineering journal (15-02-2020)
    “…•Engineering thermostable into ClpS protein variants for biotechnology applications.•Thermostable ClpS variants retain original N-terminal amino acid…”
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    Journal Article
  5. 5

    Leveraging nature’s biomolecular designs in next-generation protein sequencing reagent development by Tullman, Jennifer, Marino, John P., Kelman, Zvi

    Published in Applied microbiology and biotechnology (01-09-2020)
    “…Next-generation approaches for protein sequencing are now emerging that could have the potential to revolutionize the field in proteomics. One such sequencing…”
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    Journal Article
  6. 6

    Engineering ClpS for selective and enhanced N-terminal amino acid binding by Tullman, Jennifer, Callahan, Nicholas, Ellington, Benjamin, Kelman, Zvi, Marino, John P.

    Published in Applied microbiology and biotechnology (01-03-2019)
    “…One of the central challenges in the development of single-molecule protein sequencing technologies is achieving high-fidelity sequential recognition and…”
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    Journal Article
  7. 7

    Real-time dynamic single-molecule protein sequencing on an integrated semiconductor device by Reed, Brian D, Meyer, Michael J, Abramzon, Valentin, Ad, Omer, Adcock, Pat, Ahmad, Faisal R, Alppay, Gün, Ball, James A, Beach, James, Belhachemi, Dominique, Bellofiore, Anthony, Bellos, Michael, Beltrán, Juan Felipe, Betts, Andrew, Bhuiya, Mohammad Wadud, Blacklock, Kristin, Boer, Robert, Boisvert, David, Brault, Norman D, Buxbaum, Aaron, Caprio, Steve, Choi, Changhoon, Christian, Thomas D, Clancy, Robert, Clark, Joseph, Connolly, Thomas, Croce, Kathren Fink, Cullen, Richard, Davey, Mel, Davidson, Jack, Elshenawy, Mohamed M, Ferrigno, Michael, Frier, Daniel, Gudipati, Saketh, Hamill, Stephanie, He, Zhaoyu, Hosali, Sharath, Huang, Haidong, Huang, Le, Kabiri, Ali, Kriger, Gennadiy, Lathrop, Brittany, Li, An, Lim, Peter, Liu, Stephen, Luo, Feixiang, Lv, Caixia, Ma, Xiaoxiao, McCormack, Evan, Millham, Michele, Nani, Roger, Pandey, Manjula, Parillo, John, Patel, Gayatri, Pike, Douglas H, Preston, Kyle, Pichard-Kostuch, Adeline, Rearick, Kyle, Rearick, Todd, Ribezzi-Crivellari, Marco, Schmid, Gerard, Schultz, Jonathan, Shi, Xinghua, Singh, Badri, Srivastava, Nikita, Stewman, Shannon F, Thurston, T R, Trioli, Philip, Tullman, Jennifer, Wang, Xin, Wang, Yen-Chih, Webster, Eric A G, Zhang, Zhizhuo, Zuniga, Jorge, Patel, Smita S, Griffiths, Andrew D, van Oijen, Antoine M, McKenna, Michael, Dyer, Matthew D, Rothberg, Jonathan M

    “…Studies of the proteome would benefit greatly from methods to directly sequence and digitally quantify proteins and detect posttranslational modifications with…”
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    Journal Article
  8. 8

    Enzymatic protein switches built from paralogous input domains by Tullman, Jennifer, Nicholes, Nathan, Dumont, Matt R., Ribeiro, Lucas F., Ostermeier, Marc

    Published in Biotechnology and bioengineering (01-04-2016)
    “…ABSTRACT Protein switches have a variety of potential applications in biotechnology and medicine that motivate efforts to accelerate their development…”
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    Journal Article
  9. 9

    Protein switches identified from diverse insertion libraries created using S1 nuclease digestion of supercoiled-form plasmid DNA by Tullman, Jennifer, Guntas, Gurkan, Dumont, Matthew, Ostermeier, Marc

    Published in Biotechnology and bioengineering (01-11-2011)
    “…We demonstrate that S1 nuclease converts supercoiled plasmid DNA to unit‐length, linear dsDNA through the creation of a single, double‐stranded break in a…”
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    Journal Article
  10. 10

    Protein switch engineering by domain insertion by Kanwar, Manu, Wright, R Clay, Date, Amol, Tullman, Jennifer, Ostermeier, Marc

    Published in Methods in enzymology (2013)
    “…The switch-like regulation of protein activity by molecular signals is abundant in native proteins. The ability to engineer proteins with novel regulation has…”
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    Journal Article
  11. 11

    Design rules for protein switch construction and the creation of periplasmic binding protein-beta-lactamase switches by Tullman, Jennifer

    Published 01-01-2011
    “…Protein engineering techniques can be used to create novel allosterically regulated enzymes by fusing two naturally occurring proteins so that the activity of…”
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    Dissertation
  12. 12
  13. 13

    A xylose-stimulated xylanase-xylose binding protein chimera created by random nonhomologous recombination by Ribeiro, Lucas Ferreira, Tullman, Jennifer, Nicholes, Nathan, Silva, Sérgio Ruschi Bergamachi, Vieira, Davi Serradella, Ostermeier, Marc, Ward, Richard John

    Published in Biotechnology for biofuels (06-06-2016)
    “…Saccharification of lignocellulosic material by xylanases and other glycoside hydrolases is generally conducted at high concentrations of the final reaction…”
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    Journal Article
  14. 14

    Design rules for protein switch construction and the creation of periplasmic binding protein-beta-lactamase switches by Tullman, Jennifer

    “…Protein engineering techniques can be used to create novel allosterically regulated enzymes by fusing two naturally occurring proteins so that the activity of…”
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    Dissertation
  15. 15

    Insertion of a xylanase in xylose binding protein results in a xylose-stimulated xylanase by Ribeiro, Lucas Ferreira, Nicholes, Nathan, Tullman, Jennifer, Ribeiro, Liliane Fraga Costa, Fuzo, Carlos Alessandro, Vieira, Davi Serradella, Furtado, Gilvan Pessoa, Ostermeier, Marc, Ward, Richard John

    Published in Biotechnology for biofuels (15-08-2015)
    “…Product inhibition can reduce catalytic performance of enzymes used for biofuel production. Different mechanisms can cause this inhibition and, in most cases,…”
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    Journal Article