Search Results - "Tullio, Pascal De"

Codon-specific translation reprogramming promotes resistance to targeted therapy by Rapino, Francesca, Delaunay, Sylvain, Rambow, Florian, Zhou, Zhaoli, Tharun, Lars, De Tullio, Pascal, Sin, Olga, Shostak, Kateryna, Schmitz, Sebastian, Piepers, Jolanda, Ghesquière, Bart, Karim, Latifa, Charloteaux, Benoit, Jamart, Diane, Florin, Alexandra, Lambert, Charles, Rorive, Andrée, Jerusalem, Guy, Leucci, Eleonora, Dewaele, Michael, Vooijs, Marc, Leidel, Sebastian A., Georges, Michel, Voz, Marianne, Peers, Bernard, Büttner, Reinhard, Marine, Jean-Christophe, Chariot, Alain, Close, Pierre

“…Reprogramming of mRNA translation has a key role in cancer development and drug resistance 1 . However, the molecular mechanisms that are involved in this…”
Get full text

Blocking Lipid Synthesis Overcomes Tumor Regrowth and Metastasis after Antiangiogenic Therapy Withdrawal by Sounni, Nor Eddine, Cimino, Jonathan, Blacher, Silvia, Primac, Irina, Truong, Alice, Mazzucchelli, Gabriel, Paye, Alexandra, Calligaris, David, Debois, Delphine, De Tullio, Pascal, Mari, Bernard, De Pauw, Edwin, Noel, Agnes

“…The molecular mechanisms responsible for the failure of antiangiogenic therapies and how tumors adapt to these therapies are unclear. Here, we applied…”
Get full text

Radiotherapy-Activated Cancer-Associated Fibroblasts Promote Tumor Progression through Paracrine IGF1R Activation by Tommelein, Joke, De Vlieghere, Elly, Verset, Laurine, Melsens, Elodie, Leenders, Justine, Descamps, Benedicte, Debucquoy, Annelies, Vanhove, Christian, Pauwels, Patrick, Gespach, Christian P, Vral, Anne, De Boeck, Astrid, Haustermans, Karin, de Tullio, Pascal, Ceelen, Wim, Demetter, Pieter, Boterberg, Tom, Bracke, Marc, De Wever, Olivier

“…Preoperative radiotherapy (RT) is a mainstay in the management of rectal cancer, a tumor characterized by desmoplastic stroma containing cancer-associated…”
Get full text

Nuclear Magnetic Resonance Metabolomic Profiling of Mouse Kidney, Urine and Serum Following Renal Ischemia/Reperfusion Injury by Jouret, François, Leenders, Justine, Poma, Laurence, Defraigne, Jean-Olivier, Krzesinski, Jean-Marie, de Tullio, Pascal

“…Ischemia/reperfusion (I/R) is the most common cause of acute kidney injury (AKI). Its pathophysiology remains unclear. Metabolomics is dedicated to identify…”
Get full text

Correction: Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis by Nokin, Marie-Julie, Durieux, Florence, Peixoto, Paul, Chiavarina, Barbara, Peulen, Olivier, Blomme, Arnaud, Turtoi, Andrei, Costanza, Brunella, Smargiasso, Nicolas, Baiwir, Dominique, Scheijen, Jean L, Schalkwijk, Casper G, Leenders, Justine, De Tullio, Pascal, Bianchi, Elettra, Thiry, Marc, Uchida, Koji, Spiegel, David A, Cochrane, James R, Hutton, Craig A, De Pauw, Edwin, Delvenne, Philippe, Belpomme, Dominique, Castronovo, Vincent, Bellahcène, Akeila

Get full text

Correction: Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis by Nokin, Marie-Julie, Durieux, Florence, Peixoto, Paul, Chiavarina, Barbara, Peulen, Olivier, Blomme, Arnaud, Turtoi, Andrei, Costanza, Brunella, Smargiasso, Nicolas, Baiwir, Dominique, Scheijen, Jean L, Schalkwijk, Casper G, Leenders, Justine, De Tullio, Pascal, Bianchi, Elettra, Thiry, Marc, Uchida, Koji, Spiegel, David A, Cochrane, James R, Hutton, Craig A, De Pauw, Edwin, Delvenne, Philippe, Belpomme, Dominique, Castronovo, Vincent, Bellahcène, Akeila

Get full text

Gut Microbiota and Fecal Levels of Short-Chain Fatty Acids Differ Upon 24-Hour Blood Pressure Levels in Men by Huart, Justine, Leenders, Justine, Taminiau, Bernard, Descy, Julie, Saint-Remy, Annie, Daube, Georges, Krzesinski, Jean-Marie, Melin, Pierrette, de Tullio, Pascal, Jouret, François

“…Gut microbiota may influence blood pressure (BP), namely via end products of carbohydrate fermentation. After informed consent, male volunteers were…”
Get full text

Transforming growth factor beta‐induced, an extracellular matrix interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration by Costanza, Brunella, Rademaker, Gilles, Tiamiou, Assia, De Tullio, Pascal, Leenders, Justine, Blomme, Arnaud, Bellier, Justine, Bianchi, Elettra, Turtoi, Andrei, Delvenne, Philippe, Bellahcène, Akeila, Peulen, Olivier, Castronovo, Vincent

“…Pancreatic ductal adenocarcinoma (PDAC) remains a deadly malignancy with no efficient therapy available up‐to‐date. Glycolysis is the main provider of…”
Get full text

Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells by Rademaker, Gilles, Boumahd, Yasmine, Peiffer, Raphaël, Anania, Sandy, Wissocq, Tom, Liégeois, Maude, Luis, Géraldine, Sounni, Nor Eddine, Agirman, Ferman, Maloujahmoum, Naïma, De Tullio, Pascal, Thiry, Marc, Bellahcène, Akeila, Castronovo, Vincent, Peulen, Olivier

“…Myoferlin, an emerging oncoprotein, has been associated with a low survival in several cancer types including pancreas ductal adenocarcinoma where it controls…”
Get full text

Nuclear Magnetic Resonance Spectroscopy in Clinical Metabolomics and Personalized Medicine: Current Challenges and Perspectives by Letertre, Marine P. M., Giraudeau, Patrick, de Tullio, Pascal

“…Personalized medicine is probably the most promising area being developed in modern medicine. This approach attempts to optimize the therapies and the patient…”
Get full text

7‑Phenoxy-Substituted 3,4-Dihydro‑2H‑1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α‑Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency by Goffin, Eric, Drapier, Thomas, Larsen, Anja Probst, Geubelle, Pierre, Ptak, Christopher P, Laulumaa, Saara, Rovinskaja, Karoline, Gilissen, Julie, Tullio, Pascal de, Olsen, Lars, Frydenvang, Karla, Pirotte, Bernard, Hanson, Julien, Oswald, Robert E, Kastrup, Jette Sandholm, Francotte, Pierre

“…We report here the synthesis of 7-phenoxy-substituted 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides and their evaluation as AMPA receptor positive…”
Get full text

CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury by Yakulov, Toma A., Todkar, Abhijeet P., Slanchev, Krasimir, Wiegel, Johannes, Bona, Alexandra, Groß, Martin, Scholz, Alexander, Hess, Isabell, Wurditsch, Anne, Grahammer, Florian, Huber, Tobias B., Lecaudey, Virginie, Bork, Tillmann, Hochrein, Jochen, Boerries, Melanie, Leenders, Justine, de Tullio, Pascal, Jouret, François, Kramer-Zucker, Albrecht, Walz, Gerd

“…Kidney injury is a common complication of severe disease. Here, we report that injuries of the zebrafish embryonal kidney are rapidly repaired by a migratory…”
Get full text

Trypanosoma brucei: Metabolomics for analysis of cellular metabolism and drug discovery by Fall, Fanta, Mamede, Lucia, Schioppa, Laura, Ledoux, Allison, De Tullio, Pascal, Michels, Paul, Frédérich, Michel, Quetin-Leclercq, Joëlle

“…Background Trypanosoma brucei is the causative agent of Human African Trypanosomiasis (also known as sleeping sickness), a disease causing serious neurological…”
Get full text

Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis by Nokin, Marie-Julie, Durieux, Florence, Peixoto, Paul, Chiavarina, Barbara, Peulen, Olivier, Blomme, Arnaud, Turtoi, Andrei, Costanza, Brunella, Smargiasso, Nicolas, Baiwir, Dominique, Scheijen, Jean L, Schalkwijk, Casper G, Leenders, Justine, De Tullio, Pascal, Bianchi, Elettra, Thiry, Marc, Uchida, Koji, Spiegel, David A, Cochrane, James R, Hutton, Craig A, De Pauw, Edwin, Delvenne, Philippe, Belpomme, Dominique, Castronovo, Vincent, Bellahcène, Akeila

“…Metabolic reprogramming toward aerobic glycolysis unavoidably induces methylglyoxal (MG) formation in cancer cells. MG mediates the glycation of proteins to…”
Get full text

Effect of Head-to-Head Addition in Vinyl Acetate Controlled Radical Polymerization: Why Is Co(acac)2‑Mediated Polymerization so Much Better? by Morin, Aurélie N, Detrembleur, Christophe, Jérôme, Christine, De Tullio, Pascal, Poli, Rinaldo, Debuigne, Antoine

“…The controlled polymerization of vinyl acetate has been recently achieved by several techniques, but PVAc with targeted M n and low dispersity up to very high…”
Get full text

Novel XBP1s-independent function of IRE1 RNase in HIF-1α-mediated glycolysis upregulation in human macrophages upon stimulation with LPS or saturated fatty acid by Iovino, Margaud, Colonval, Megan, Wilkin, Chloé, L’homme, Laurent, Lassence, Cédric, Campas, Manon, Peulen, Olivier, de Tullio, Pascal, Piette, Jacques, Legrand-Poels, Sylvie

“…In obesity, adipose tissue infiltrating macrophages acquire a unique pro-inflammatory polarization, thereby playing a key role in the development of chronic…”
Get full text

Pyruvate dehydrogenase kinase/lactate axis: a therapeutic target for neovascular age-related macular degeneration identified by metabolomics by Lambert, Vincent, Hansen, Sylvain, Schoumacher, Matthieu, Lecomte, Julie, Leenders, Justine, Hubert, Pascale, Herfs, Michael, Blacher, Silvia, Carnet, Oriane, Yip, Cassandre, Blaise, Pierre, Duchateau, Edouard, Locht, Bénédicte, Thys, Michèle, Cavalier, Etienne, Gothot, André, Govaerts, Bernadette, Rakic, Jean-Marie, Noel, Agnès, de Tullio, Pascal

“…Neovascular age-related macular degeneration (nAMD) is the leading cause of blindness in aging populations. Here, we applied metabolomics to human sera of…”
Get full text

Recent metabolomic developments for antimalarial drug discovery by Mamede, Lúcia, Fall, Fanta, Schoumacher, Matthieu, Ledoux, Allison, De Tullio, Pascal, Quetin-Leclercq, Joëlle, Frédérich, Michel

“…Malaria is a parasitic disease that remains a global health issue, responsible for a significant death and morbidity toll. Various factors have impacted the…”
Get full text

The Budesonide-Hydroxypropyl-β-Cyclodextrin Complex Attenuates ROS Generation, IL-8 Release and Cell Death Induced by Oxidant and Inflammatory Stress. Study on A549 and A-THP-1 Cells by Bayiha, Jules César, Evrard, Brigitte, Cataldo, Didier, De Tullio, Pascal, Mingeot-Leclercq, Marie-Paule

“…Synthetic glucocorticoids such as budesonide (BUD) are potent anti-inflammatory drugs commonly used to treat patients suffering from chronic inflammatory…”
Get full text

Combining rapid 2D NMR experiments with novel pre-processing workflows and MIC quality measures for metabolomics by Féraud, Baptiste, Martineau, Estelle, Leenders, Justine, Govaerts, Bernadette, de Tullio, Pascal, Giraudeau, Patrick

“…Introduction The use of 2D NMR data sources (COSY in this paper) allows to reach general metabolomics results which are at least as good as the results…”
Get full text