Search Results - "Tuhácková, Z"

Molecular therapeutics--lessons from the role of Src in cellular signalling by Tuhácková, Z

“…Src is the oldest and best studied protooncogene participating in normal cells in proliferation, maintenance of normal intercellular contacts and cell…”
Get full text

Expression and interaction of different catenins in colorectal carcinoma cells by Kucerová, D, Sloncová, E, Tuhácková, Z, Vojtechová, M, Sovová, V

“…Aberrant signalling activities of beta-catenin, originally identified as a component of cell-adhesion complexes, are now considered to be an important factor…”
Get more information

Rapamycin‐resistant phosphorylation of the initiation factor‐4E‐binding protein (4E‐BP1) in v‐SRC‐transformed hamster fibroblasts by Tuháčková, Zdena, Sovová, Vlasta, Šloncová, Eva, Proud, Christopher G.

“…Increased phosphorylation of the translational repressor protein 4E‐BP1 was found in the cell line derived from the tumor induced in Syrian hamster by Rous…”
Get full text

Changes of E-cadherin and beta-catenin levels during induced differentiation of colorectal carcinoma cells by Kucerová, D, Sloncová, E, Tuhácková, Z, Uhlírová, M, Kos, M, Sovová, V

“…Following the finding of a great increase in cell-cell adhesion in several colorectal carcinoma cell lines after induced differentiation, the expression of…”
Get more information

GTP, a Nonsubstrate of ATP Citrate Lyase, Is a Phosphodonor for the Enzyme Histidine Autophosphorylation by Tuháčková, Zdena, Křivánek, Jiřı́

“…ATP citrate lyase (EC 4.3.1.8.) was shown to be a major phosphorylated protein of a fraction derived from Zajdela rat hepatoma by chromatography on…”
Get full text

Inhibition of mTORC1 by SU6656, the selective Src kinase inhibitor, is not accompanied by activation of Akt/PKB signalling in melanoma cells by Ondrušová, L, Réda, J, Záková, P, Tuháčková, Z

“…The mammalian target of rapamycin (mTOR) is a Ser/Thr protein kinase conserved in all eukaryotes that plays a key role in cell growth and is a central effector…”
Get full text

Changes of E-cadherin and beta-catenin in human and mouse intestinal tumours by Sloncová, E, Fric, P, Kucerová, D, Lojda, Z, Tuhácková, Z, Sovová, V

“…An immunohistochemical analysis of E-cadherin and beta-catenin was performed in human colorectal cancer as well as in surrounding normal intestinal tissue. We…”
Get more information

Inhibition of mTORCl by SU6656, the Selective Src Kinase Inhibitor, Is Not Accompanied by Activation of Akt/PKB Signalling in Melanoma Cells by Ondrusová, L, Réda, J, Záková, P, Tuhácková, Z

“…The mammalian target of rapamycin (mTOR) is a Ser/Thr protein kinase conserved in all eukaryotes that plays a key role in cell growth and is a central effector…”
Get full text

Guanosine triphosphate - dependent autocatalytic phosphorylation of peptide initiation factor 2 from rat liver by Tuhácková, Z, Hradec, J

Get more information

The transmembrane signalling by Tuhácková, Z

Get more information

Activity of glycogen synthase kinase-3beta is down-regulated during transient differentiation of human colon cancer HT-29 cells by Tuhackova, Z, Sloncova, E, Hlavacek, J, Sovova, V, Velek, J

“…The increased phosphorylation and activity of protein kinase B (PKB/Akt) was found early upon butyrate treatment of HT-29 cells with a potent differentiating…”
Get more information

Cholesteryl esters are bound by a peptide-initiation and a peptide-elongation factor by Tuhácková, Z, Hradec, J

“…Significantly higher quantities of cholesteryl 14-methylhexadecanoate than of cholesteryl laurate and cholesteryl palmitate are bound by a homogeneous…”
Get full text

Staurosporine and gossypol are inhibitors of the function of peptide elongation factor 1 alpha from rabbit reticulocytes by Tuhácková, Z

“…As it has been found, the incubation of [gamma-32P]ATP with elongation factor--1 alpha purified from rabbit reticulocytes resulted in the phosphorylation of…”
Get more information

CTP can replace GTP in reactions catalyzed by eukaryotic peptide elongation factor 1 by Tuháčková, Z., Havránek, M., Hradec, J.

“…In several reactions catalyzed by highly purified peptide elongation factor 1 from rabbit reticulocytes, GTP may be fully replaced by CTP but not by ATP or…”
Get full text

Decreased activity of peptide-elongation factors after treatment with cholesterol esterase by Hradec, J, Tuhácková, Z, Dusek, Z

“…1. Peptide-elongation factors were purified from rat liver and treated with cholesterol esterase and phospholipase A2 immobilized on Sepharose 4B. 2. Binding…”
Get full text

Enhanced utilization of 14-methylhexadecanoic acid for the synthesis of lipids during the growth of Walker 256 carcinoma in rats by Tuhácková, Z, Gryga, P, Helmich, O, Dusek, Z, Hradec, J

“…Labeled 14-methylhexadecanoic acid was administered to normal rats, animals bearing the Walker 256 tumor at various stages of its growth and to tumor-resistant…”
Get full text

Purification and some properties of a protein factor binding and deacylating initiator transfer ribonucleic acid by Pohlreich, P, Kríz, O, Tuhácková, Z, Dusek, Z, Hradec, J

“…1. A protein factor promoting the binding of initiator tRNA to the 40S ribosomal subunit was purified to homogeneity (more than 2500-fold) from rat liver…”
Get full text

Regulation of the activity of eukaryotic peptide elongation factor 1 by autocatalytic phosphorylation by TUHÁČKOVÁ, Zdena, ULLRICHOVÁ, Jitka, HRADEC, Jan

“…Highly purified peptide elongation factor 1 from rabbit reticulocytes liberates the terminal phosphate from [γ‐32P]GTP and incorporates it into its own…”
Get full text

IL2-dependent phosphorylation of 40S ribosomal protein S6 is controlled by PI-3K/mTOR signalling in CTLL2 cells by Tuhácková, Zdena, Sloncová, Eva, Vojtechová, Martina, Sovová, Vlasta

“…Growth factors and hormones activate global and selective protein translation by phosphorylation and therefore activation of p70 S6 kinase through a…”
Get more information

Characterization of four clones derived from human adenocarcinoma cell line, HT29, and analysis of their response to sodium butyrate by STOKROVA, Jitka, SLONCOVA, Eva, SOVOVA, Vlasta, KUCEROVA, Dana, ZILA, Vojtech, TURECKOVA, Jolana, VOJTECHOVA, Martina, KORB, Jan, TUHACKOVA, Zdena

“…The differentiation of colorectal cancer cells is associated with the arrest of tumor growth and tumor regression. However, the mechanism of such tumor cell…”
Get full text