Search Results - "Tufveson, Gunnar"
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IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation
Published in The New England journal of medicine (03-08-2017)“…In this study, an IgG-degrading enzyme derived from Streptococcus pyogenes (IdeS) that cleaves human IgG into F(ab′) 2 and Fc fragments reduced or eliminated…”
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Donor-derived urologic cancers after renal transplantation: A retrospective non-randomized scientific analysis
Published in PloS one (21-09-2022)“…Background Malignancies in the urinary tract and the kidney graft are quite common after kidney transplantation. In some selected cases tumours develop from…”
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Safety, immunogenicity, pharmacokinetics, and efficacy of degradation of anti‐HLA antibodies by IdeS (imlifidase) in chronic kidney disease patients
Published in American journal of transplantation (01-11-2018)“…Safety, immunogenicity, pharmacokinetics, and efficacy of the IgG‐degrading enzyme of Streptococcus pyogenes (IdeS [imlifidase]) were assessed in a…”
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Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation
Published in Transplantation (01-03-2019)“…BACKGROUND.When transplanted human pancreatic islets are exposed to blood during intraportal infusion, an innate immune response is triggered. This instant…”
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Intratumoral immunostimulatory AdCD40L gene therapy in patients with advanced solid tumors
Published in Cancer gene therapy (01-11-2021)“…AdCD40L is a replication-deficient virus carrying the gene for CD40 ligand which has previously been evaluated in patients with urothelial cancer and malignant…”
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A Randomized, Doubleblind, Placebo-Controlled, Study of Single-Dose Rituximab as Induction in Renal Transplantation
Published in Transplantation (15-05-2009)“…We performed a prospective, double blind, randomized, placebo-controlled multicenter study on the efficacy and safety of rituximab as induction therapy,…”
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Islet Surface Heparinization Prevents the Instant Blood-Mediated Inflammatory Reaction in Islet Transplantation
Published in Diabetes (New York, N.Y.) (01-08-2007)“…Islet Surface Heparinization Prevents the Instant Blood-Mediated Inflammatory Reaction in Islet Transplantation Sanja Cabric 1 , Javier Sanchez 1 , Torbjörn…”
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Tissue Factor Produced by the Endocrine Cells of the Islets of Langerhans Is Associated With a Negative Outcome of Clinical Islet Transplantation
Published in Diabetes (New York, N.Y.) (01-06-2005)“…Tissue Factor Produced by the Endocrine Cells of the Islets of Langerhans Is Associated With a Negative Outcome of Clinical Islet Transplantation Helena…”
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Modifying the vessel walls in porcine kidneys during machine perfusion
Published in The Journal of surgical research (01-10-2014)“…Abstract Background Endothelial glycocalyx regulates the endothelial function and plays an active role in maintaining vascular homeostasis. During ischema and…”
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Refinement of the automated method for human islet isolation and presentation of a closed system for in vitro islet culture
Published in Transplantation (15-11-2004)“…The procedure of human islet isolation needs further optimization and standardization. Here, we describe techniques to enhance enzymatic digestion and minimize…”
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Prompt reversal of a severe complement activation by eculizumab in a patient undergoing intentional ABO-incompatible pancreas and kidney transplantation
Published in Transplant international (01-08-2011)“…We describe the presumably first intentional ABO-incompatible deceased-donor kidney and pancreas transplantation with a severe antibody-mediated rejection…”
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Calcium
Published in Cell transplantation (01-07-2018)“…Background: Effective digestive enzymes are crucial for successful islet isolation. Supplemental proteases are essential because they synergize with…”
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Evaluation of Perfluorohexyloctane/Polydimethylsiloxane for Pancreas Preservation for Clinical Islet Isolation and Transplantation
Published in Cell transplantation (01-01-2016)“…This study aimed to evaluate a 50:50 mix of perfluorohexyloctane/polydimethylsiloxane 5 (F6H8S5) preservation of pancreases in a clinical setting compared with…”
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Using HTK for Prolonged Pancreas Preservation Prior to Human Islet Isolation
Published in The Journal of surgical research (01-06-2012)“…Background Histidine-tryptophan-ketoglutarate (HTK) has been established as an alternative to University-of-Wisconsin solution (UWS) for abdominal organ…”
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The Importance of Tryptic-like Activity in Purified Enzyme Blends for Efficient Islet Isolation
Published in Transplantation (15-02-2009)“…The isolation of islets from the human pancreas critically depends on an efficient enzyme blend. Previous studies have solely focused on the presence of…”
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Islet engraftment and revascularization in clinical and experimental transplantation
Published in Cell transplantation (01-01-2013)“…Proper revascularization after transplantation is assumed to be crucial for appropriate islet graft function. We developed a novel noninvasive imaging method,…”
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Screening of mortality in transplant patients using an assay for immune function
Published in Transplant immunology (01-05-2011)“…Abstract Background So far, the ImmuKnow Immune Cell Function Assay (Cylex, Inc., Columbia, MD, USA) has been used to assess risks of infection and rejection…”
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Liver regeneration is impaired by FK778 in partially hepatectomized rats, while supplemental uridine restores both liver growth and hepatocyte proliferation
Published in Hepatology research (01-01-2009)“…Aim: The impact of mandatory immunosuppression on liver regeneration after segmental liver transplantation is of clinical importance. FK778, a novel…”
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A New Oxygen Carrier for Improved Long-Term Storage of Human Pancreata Before Islet Isolation
Published in Transplantation (27-01-2010)Get full text
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