Search Results - "Tuerk, Roland D."
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1
β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells
Published in The Journal of biological chemistry (20-07-2018)“…Our previous work has established that the metabolic sensor AMP-activated protein kinase (AMPK) inhibits the epithelial Na+ channel (ENaC) by promoting its…”
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2
New Candidate Targets of AMP-Activated Protein Kinase in Murine Brain Revealed by a Novel Multidimensional Substrate-Screen for Protein Kinases
Published in Journal of proteome research (01-08-2007)“…AMP-activated protein kinase (AMPK) is a heterotrimeric serine/threonine kinase that is involved in the maintenance of energy homeostasis and recovery from…”
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3
PKA phosphorylates and inactivates AMPKα to promote efficient lipolysis
Published in The EMBO journal (20-01-2010)“…The mobilization of metabolic energy from adipocytes depends on a tightly regulated balance between hydrolysis and resynthesis of triacylglycerides (TAGs)…”
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4
Tracking and quantification of 32P-labeled phosphopeptides in liquid chromatography matrix-assisted laser desorption/ionization mass spectrometry
Published in Analytical biochemistry (15-07-2009)“…Phosphoamino acid modifications on substrate proteins are critical components of protein kinase signaling pathways. Thus, diverse methodologies have been…”
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5
Homo-oligomerization and Activation of AMP-activated Protein Kinase Are Mediated by the Kinase Domain αG-Helix
Published in The Journal of biological chemistry (02-10-2009)“…AMP-activated protein kinase (AMPK) is a heterotrimeric complex playing a crucial role in maintaining cellular energy homeostasis. Recently, homodimerization…”
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6
Novel candidate substrates of AMP-activated protein kinase identified in red blood cell lysates
Published in Biochemical and biophysical research communications (23-07-2010)“…► Nickel-affinity chromatography for hemoglobin removal from red blood cell lysates. ► AMP-activated protein kinase substrate identification in red blood cell…”
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7
Homo-oligomerization and activation of AMP-activated protein kinase are mediated by the kinase domain alphaG-helix
Published in The Journal of biological chemistry (02-10-2009)“…AMP-activated protein kinase (AMPK) is a heterotrimeric complex playing a crucial role in maintaining cellular energy homeostasis. Recently, homodimerization…”
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Journal Article -
8
Dissecting the Role of 5′-AMP for Allosteric Stimulation, Activation, and Deactivation of AMP-activated Protein Kinase
Published in The Journal of biological chemistry (27-10-2006)“…AMP-activated protein kinase (AMPK) is a heterotrimeric protein kinase that is crucial for cellular energy homeostasis of eukaryotic cells and organisms. Here…”
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9
Regulation of brain-type creatine kinase by AMP-activated protein kinase: Interaction, phosphorylation and ER localization
Published in Biochimica et biophysica acta (01-08-2014)“…AMP-activated protein kinase (AMPK) and cytosolic brain-type creatine kinase (BCK) cooperate under energy stress to compensate for loss of adenosine…”
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10
β 1 Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells
Published in The Journal of biological chemistry (20-07-2018)“…Our previous work has established that the metabolic sensor AMP-activated protein kinase (AMPK) inhibits the epithelial Na channel (ENaC) by promoting its…”
Get full text
Journal Article -
11
PKA phosphorylates and inactivates AMPK[alpha] to promote efficient lipolysis
Published in The EMBO journal (20-01-2010)“…The mobilization of metabolic energy from adipocytes depends on a tightly regulated balance between hydrolysis and resynthesis of triacylglycerides (TAGs)…”
Get full text
Journal Article -
12
Homo-oligomerization and Activation of AMP-activated Protein Kinase Are Mediated by the Kinase Domain αG-Helix
Published in The Journal of biological chemistry (02-10-2009)“…AMP-activated protein kinase (AMPK) is a heterotrimeric complex playing a crucial role in maintaining cellular energy homeostasis. Recently, homodimerization…”
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Journal Article -
13
An automated home-built low-cost fermenter suitable for large-scale bacterial expression of proteins in Escherichia coli
Published in BioTechniques (01-08-2008)“…We have developed an automated fermentation system for cost-efficient upscaling of protein expression in bacteria. The system, built for use by…”
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14
PKA phosphorylates and inactivates AMPKalpha to promote efficient lipolysis
Published in The EMBO journal (20-01-2010)“…The mobilization of metabolic energy from adipocytes depends on a tightly regulated balance between hydrolysis and resynthesis of triacylglycerides (TAGs)…”
Get full text
Journal Article