Clinical and research markers of oxidative stress in chronic kidney disease

Clinical and research markers of oxidative stress in chronic kidney disease

Abstract Context: Kidney-related pathologies have increasing prevalence rates, produce a considerable financial burden, and are characterized by elevated levels of oxidative stress (OS). Objective: This review examines relationships between chronic kidney disease (CKD) and markers of OS and antioxid...

Full description

Saved in:
Bibliographic Details
Published in:Biomarkers Vol. 18; no. 2; pp. 103 - 115
Main Authors: Tucker, Patrick Steven, Dalbo, Vincent James, Han, Thin, Kingsley, Michael Ian
Format: Journal Article
Language:English
Published: England Informa UK, Ltd 01-03-2013
Taylor & Francis
Subjects:
Adult
Advanced Oxidation Protein Products - blood
Antioxidant status
Arginine - analogs & derivatives
Arginine - blood
Biomarkers - blood
Biomarkers - urine
Clinical Trials as Topic
Deoxyguanosine - analogs & derivatives
Deoxyguanosine - urine
F2-Isoprostanes - blood
Glutathione - blood
Humans
Kidney - metabolism
Kidney - pathology
Lipid Peroxidation
Lipid Peroxides - blood
Malondialdehyde - blood
Oxidative Stress
Protein Carbonylation
reactive nitrogen species
reactive oxygen species
renal disease
renal failure
Renal Insufficiency, Chronic - blood
Renal Insufficiency, Chronic - diagnosis
Renal Insufficiency, Chronic - pathology
Renal Insufficiency, Chronic - urine
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Context: Kidney-related pathologies have increasing prevalence rates, produce a considerable financial burden, and are characterized by elevated levels of oxidative stress (OS). Objective: This review examines relationships between chronic kidney disease (CKD) and markers of OS and antioxidant status (AS). Methods: A systematic review of MEDLINE-indexed clinical trials, randomized controlled trials and comparative studies that examined OS and AS was performed. Results and conclusion: Several markers emerged as well-suited indicators of OS and AS in CKD: malondialdehyde, F2-isoprostanes, lipid hydroperoxides, asymmetric dimethylarginine, 8-oxo-7,8-dihydro-2′-deoxyguanosine, protein carbonyls, advanced oxidation protein products and glutathione-related activity.
Bibliography:SourceType-Scholarly Journals-1
ObjectType-Feature-4
ObjectType-Undefined-1
content type line 23
ObjectType-Review-2
ObjectType-Article-3
ISSN:1354-750X
1366-5804
DOI:10.3109/1354750X.2012.749302