Search Results - "Tucker, James H. R"

Kinetin Riboside and Its ProTides Activate the Parkinson’s Disease Associated PTEN-Induced Putative Kinase 1 (PINK1) Independent of Mitochondrial Depolarization by Osgerby, Laura, Lai, Yu-Chiang, Thornton, Peter J, Amalfitano, Joseph, Le Duff, Cécile S, Jabeen, Iqra, Kadri, Hachemi, Miccoli, Ageo, Tucker, James H. R, Muqit, Miratul M. K, Mehellou, Youcef

“…Since loss of function mutations of PINK1 lead to early onset Parkinson’s disease, there has been growing interest in the discovery of small molecules that…”
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Acrylamide-dT: a polymerisable nucleoside for DNA incorporation by Allabush, Francia, Mendes, Paula M, Tucker, James H. R

“…The synthesis of a novel modified nucleoside phosphoramidite, Acrylamide-dT-CE phosphoramidite, obtained in three steps from commercially available starting…”
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Electrochemical Method for the Determination of Enantiomeric Excess of Binol Using Redox-Active Boronic Acids as Chiral Sensors by Mirri, Giorgio, Bull, Steven D, Horton, Peter N, James, Tony D, Male, Louise, Tucker, James H. R

“…A chiral ferrocene-based boronic acid interacts with (R)- and (S)-Binol to form two complexes that exhibit significantly different ferrocene-based electrode…”
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The challenges of glycan recognition with natural and artificial receptors by Tommasone, Stefano, Allabush, Francia, Tagger, Yazmin K, Norman, Joshua, Köpf, Monika, Tucker, James H R, Mendes, Paula M

“…Glycans - simple or complex carbohydrates - play key roles as recognition determinants and modulators of numerous physiological and pathological processes…”
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Exploiting anthracene photodimerization within peptides: light induced sequence-selective DNA binding by Bullen, Gemma A, Tucker, James H R, Peacock, Anna F A

“…The unprecedented use of anthracene photodimerization within a protein or peptide system is explored through its incorporation into a DNA-binding peptide,…”
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Linear Dichroism Activity of Chiral Poly(p‑Aryltriazole) Foldamers by Carter, Jake G, Pfukwa, Rueben, Riley, Liam, Tucker, James H. R, Rodger, Alison, Dafforn, Timothy R, Klumperman, Bert

“…Controllable higher-order assembly is a central aim of macromolecular chemistry. An essential challenge to developing these molecules is improving our…”
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An Exploration of Ferrocenyl Ureas as Enantioselective Electrochemical Sensors for Chiral Carboxylate Anions by Willener, Yasmine, Joly, Kévin M, Moody, Christopher J, Tucker, James H. R

“…The syntheses of a series of chiral ureas containing the redox-active ferrocene group are described. Each of these bind chiral carboxylates in organic solvents…”
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Reversible Control over Molecular Recognition in Surface-Bound Photoswitchable Hydrogen-Bonding Receptors: Towards Read-Write-Erase Molecular Printboards by Liang, Chih-Kai, Dubacheva, Galina V., Buffeteau, Thierry, Cavagnat, Dominique, Hapiot, Philippe, Fabre, Bruno, Tucker, James H. R., Bassani, Dario M.

“…The synthesis of an anthracene‐bearing photoactive barbituric acid receptor and its subsequent grafting onto azide‐terminated alkanethiol/Au self‐assembled…”
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Role of Order in the Mechanism of Charge Transport across Single-Stranded and Double-Stranded DNA Monolayers in Tunnel Junctions by Gupta, Nipun Kumar, Wilkinson, Edward A, Karuppannan, Senthil Kumar, Bailey, Lily, Vilan, Ayelet, Zhang, Ziyu, Qi, Dong-Chen, Tadich, Anton, Tuite, Eimer M, Pike, Andrew R, Tucker, James H. R, Nijhuis, Christian A

“…Deoxyribonucleic acid (DNA) has been hypothesized to act as a molecular wire due to the presence of an extended π-stack between base pairs, but the factors…”
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Structural Effects on the Ground and Excited-state Properties of Photoswitchable Hydrogen-Bonding Receptors by Molard, Yann, Bassani, Dario M, Desvergne, Jean-Pierre, Moran, Nina, Tucker, James H. R

“…The ground- and excited-state properties of a series of photochromic barbiturate receptors…”
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Interrogating Aptamer Chemical Space Through Modified Nucleotide Substitution Facilitated by Enzymatic DNA Synthesis by Niogret, Germain, Bouvier‐Müller, Alix, Figazzolo, Chiara, Joyce, Jack M., Bonhomme, Frédéric, England, Patrick, Mayboroda, Olena, Pellarin, Riccardo, Gasser, Gilles, Tucker, James H. R., Tanner, Julian A., Savage, G. Paul, Hollenstein, Marcel

“…Chemical modification of aptamers is an important step to improve their performance and stability in biological media. This can be performed either during…”
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Remote Photoregulated Ring Gliding in a [2]Rotaxane via a Molecular Effector by Tron, Arnaud, Pianet, Isabelle, Martinez-Cuezva, Alberto, Tucker, James H. R, Pisciottani, Luca, Alajarin, Mateo, Berna, Jose, McClenaghan, Nathan D

“…A molecular barbiturate messenger, which is reversibly released/captured by a photoswitchable artificial molecular receptor, is shown to act as an effector to…”
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Verteporfin selectively kills hypoxic glioma cells through iron-binding and increased production of reactive oxygen species by Eales, Katherine L., Wilkinson, Edward A., Cruickshank, Garth, Tucker, James H. R., Tennant, Daniel A.

“…Gliomas are highly malignant brain tumours characterised by extensive areas of poor perfusion which subsequently leads to hypoxia and reduced survival…”
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Organometallic nucleoside analogues: effect of the metallocene metal atom on cancer cell line toxicity by Ismail, Media K, Armstrong, Katie A, Hodder, Samantha L, Horswell, Sarah L, Male, Louise, Nguyen, Huy V, Wilkinson, Edward A, Hodges, Nikolas J, Tucker, James H R

“…A new chiral organometallic nucleoside analogue containing ruthenocene is reported, in which alkylthymine and alkylhydroxyl groups are attached in adjacent…”
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Control of Pyramidal Inversion Rates by Redox Switching by Davies, Mark W., Shipman, Michael, Tucker, James H. R., Walsh, Tiffany R.

“…The dynamics of pyramidal nitrogen inversion can be controlled by reversible redox switching in trans-2,3-diphenylaziridines bearing a suitable…”
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Organometallic Nucleoside Analogues with Ferrocenyl Linker Groups: Synthesis and Cancer Cell Line Studies by Nguyen, Huy V, Sallustrau, Antoine, Balzarini, Jan, Bedford, Matthew R, Eden, John C, Georgousi, Niki, Hodges, Nikolas J, Kedge, Jonathan, Mehellou, Youcef, Tselepis, Chris, Tucker, James H. R

“…Examples of organometallic compounds as nucleoside analogues are rare within the field of medicinal bioorganometallic chemistry. We report on the synthesis and…”
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Macrocyclic Metal Complex–DNA Conjugates for Electrochemical Sensing of Single Nucleobase Changes in DNA by Duprey, Jean-Louis H. A, Carr-Smith, James, Horswell, Sarah L, Kowalski, Jarosław, Tucker, James H. R

“…The direct incorporation of macrocyclic cyclidene complexes into DNA via automated synthesis results in a new family of metal-functionalized DNA derivatives…”
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Detection of single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer using a fluorophore-tagged DNA probe by Zhao, Zheng-yun, San, Marie, Duprey, Jean-Louis H.A., Arrand, John R., Vyle, Joseph S., Tucker, James H.R.

“…Single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer were identified using oligodeoxynucleotide probe sequences bearing…”
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Reversible Photocapture of a [2]Rotaxane Harnessing a Barbiturate Template by Tron, Arnaud, Thornton, Peter J, Lincheneau, Christophe, Desvergne, Jean-Pierre, Spencer, Neil, Tucker, James H. R, McClenaghan, Nathan D

“…Photoirradiation of a hydrogen-bonded molecular complex comprising acyclic components, namely, a stoppered thread (1) with a central barbiturate motif and an…”
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Solid-phase synthesis and structural characterisation of phosphoroselenolate-modified DNA: a backbone analogue which does not impose conformational bias and facilitates SAD X-ray crystallography by Conlon, Patrick F, Eguaogie, Olga, Wilson, Jordan J, Sweet, Jamie S. T, Steinhoegl, Julian, Englert, Klaudia, Hancox, Oliver G. A, Law, Christopher J, Allman, Sarah A, Tucker, James H. R, Hall, James P, Vyle, Joseph S

“…Oligodeoxynucleotides incorporating internucleotide phosphoroselenolate linkages have been prepared under solid-phase synthesis conditions using dimer…”
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