Search Results - "Tucker, Haley"

Induction of chronic lymphocytic leukemia-like disease in STYK1/NOK transgenic mice by Yang, Yin, Liu, Li, Tucker, Haley O.

“…STYK1/NOK functions in a ligand independent and constitutive fashion to provoke tumor formation and to be up-regulated in many types of cancer cells. However,…”
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Foxp1 controls brown/beige adipocyte differentiation and thermogenesis through regulating β3-AR desensitization by Liu, Pei, Huang, Sixia, Ling, Shifeng, Xu, Shuqin, Wang, Fuhua, Zhang, Wei, Zhou, Rujiang, He, Lin, Xia, Xuechun, Yao, Zhengju, Fan, Ying, Wang, Niansong, Hu, Congxia, Zhao, Xiaodong, Tucker, Haley O., Wang, Jiqiu, Guo, Xizhi

“…β-Adrenergic receptor (β-AR) signaling is a pathway controlling adaptive thermogenesis in brown or beige adipocytes. Here we investigate the biological roles…”
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Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart by Warren, Junco S., Tracy, Christopher M., Miller, Mickey R., Makaju, Aman, Szulik, Marta W., Oka, Shin-ichi, Yuzyuk, Tatiana N., Cox, James E., Kumar, Anil, Lozier, Bucky K., Wang, Li, Llana, June García, Sabry, Amira D., Cawley, Keiko M., Barton, Dane W., Han, Yong Hwan, Boudina, Sihem, Fiehn, Oliver, Tucker, Haley O., Zaitsev, Alexey V., Franklin, Sarah

“…Smyd1, a muscle-specific histone methyltransferase, has established roles in skeletal and cardiac muscle development, but its role in the adult heart remains…”
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Foxp1 Regulates the Proliferation of Hair Follicle Stem Cells in Response to Oxidative Stress during Hair Cycling by Zhao, Jianzhi, Li, Hanjun, Zhou, Rujiang, Ma, Gang, Dekker, Joseph D, Tucker, Haley O, Yao, Zhengju, Guo, Xizhi

“…Hair follicle stem cells (HFSCs) in the bugle circularly generate outer root sheath (ORS) through linear proliferation within limited cycles during anagen…”
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Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates by Pearson, Caroline Alayne, Moore, Destaye M., Tucker, Haley O., Dekker, Joseph D., Hu, Hui, Miquelajáuregui, Amaya, Novitch, Bennett G.

“…The laminar architecture of the mammalian neocortex depends on the orderly generation of distinct neuronal subtypes by apical radial glia (aRG) during…”
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An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development by Benitez, Cecil M, Qu, Kun, Sugiyama, Takuya, Pauerstein, Philip T, Liu, Yinghua, Tsai, Jennifer, Gu, Xueying, Ghodasara, Amar, Arda, H Efsun, Zhang, Jiajing, Dekker, Joseph D, Tucker, Haley O, Chang, Howard Y, Kim, Seung K

“…The regulatory logic underlying global transcriptional programs controlling development of visceral organs like the pancreas remains undiscovered. Here, we…”
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The malignant transformation potential of the oncogene STYK1/NOK at early lymphocyte development in transgenic mice by Yang, Yin, Liu, Li, Tucker, Haley O.

“…B-cell Chronic Lymphocytic Leukemia (B-CLL) is a malignancy caused by the clonal expansion of mature B lymphocytes bearing a CD5+CD19+ (B1) phenotype. However,…”
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Spinal Locomotor Circuits Develop Using Hierarchical Rules Based on Motorneuron Position and Identity by Hinckley, Christopher A., Alaynick, William A., Gallarda, Benjamin W., Hayashi, Marito, Hilde, Kathryn L., Driscoll, Shawn P., Dekker, Joseph D., Tucker, Haley O., Sharpee, Tatyana O., Pfaff, Samuel L.

“…The coordination of multi-muscle movements originates in the circuitry that regulates the firing patterns of spinal motorneurons. Sensory neurons rely on…”
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Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses by Rasmussen, Tara L, Ma, Yanlin, Park, Chong Yon, Harriss, June, Pierce, Stephanie A, Dekker, Joseph D, Valenzuela, Nicolas, Srivastava, Deepak, Schwartz, Robert J, Stewart, M David, Tucker, Haley O

“…Smyd1/Bop is an evolutionary conserved histone methyltransferase previously shown by conventional knockout to be critical for embryonic heart development. To…”
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FoxP1 orchestration of ASD-relevant signaling pathways in the striatum by Araujo, Daniel J, Anderson, Ashley G, Berto, Stefano, Runnels, Wesley, Harper, Matthew, Ammanuel, Simon, Rieger, Michael A, Huang, Hung-Chung, Rajkovich, Kacey, Loerwald, Kristofer W, Dekker, Joseph D, Tucker, Haley O, Dougherty, Joseph D, Gibson, Jay R, Konopka, Genevieve

“…Mutations in the transcription factor Forkhead box p1 (FOXP1) are causative for neurodevelopmental disorders such as autism. However, the function of FOXP1…”
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ARID3A is required for mammalian placenta development by Rhee, Catherine, Edwards, Melissa, Dang, Christine, Harris, June, Brown, Mark, Kim, Jonghwan, Tucker, Haley O.

“…Previous studies in the mouse indicated that ARID3A plays a critical role in the first cell fate decision required for generation of trophectoderm (TE). Here,…”
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Mechanisms of transcription factor-mediated direct reprogramming of mouse embryonic stem cells to trophoblast stem-like cells by Rhee, Catherine, Lee, Bum-Kyu, Beck, Samuel, LeBlanc, Lucy, Tucker, Haley O, Kim, Jonghwan

“…Direct reprogramming can be achieved by forced expression of master transcription factors. Yet how such factors mediate repression of initial…”
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Dendritic cell fate is determined by BCL11A by Ippolito, Gregory C., Dekker, Joseph D., Wang, Yui-Hsi, Lee, Bum-Kyu, Shaffer, Arthur L., Lin, IllJian, Wall, Jason K., Lee, Baeck-Seung, Staudt, Louis M., Liu, Yong-Jun, Iyer, Vishwanath R., Tucker, Haley O.

“…The plasmacytoid dendritic cell (pDC) is vital to the coordinated action of innate and adaptive immunity. pDC development has not been unequivocally traced,…”
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Foxp1 in Forebrain Pyramidal Neurons Controls Gene Expression Required for Spatial Learning and Synaptic Plasticity by Araujo, Daniel J, Toriumi, Kazuya, Escamilla, Christine O, Kulkarni, Ashwinikumar, Anderson, Ashley G, Harper, Matthew, Usui, Noriyoshi, Ellegood, Jacob, Lerch, Jason P, Birnbaum, Shari G, Tucker, Haley O, Powell, Craig M, Konopka, Genevieve

“…Genetic perturbations of the transcription factor ( ) are causative for severe forms of autism spectrum disorder that are often comorbid with intellectual…”
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Ctip1 Regulates the Balance between Specification of Distinct Projection Neuron Subtypes in Deep Cortical Layers by Woodworth, Mollie B., Greig, Luciano C., Liu, Kevin X., Ippolito, Gregory C., Tucker, Haley O., Macklis, Jeffrey D.

“…The molecular linkage between neocortical projection neuron subtype and area development, which enables the establishment of functional areas by projection…”
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Established and Evolving Roles of the Multifunctional Non-POU Domain-Containing Octamer-Binding Protein (NonO) and Splicing Factor Proline- and Glutamine-Rich (SFPQ) by Yu, Danyang, Huang, Ching-Jung, Tucker, Haley O

“…It has been more than three decades since the discovery of multifunctional factors, the Non-POU-Domain-Containing Octamer-Binding Protein, NonO, and the…”
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Polyethylene glycol‐fusion repair of sciatic allografts in female rats achieves immunotolerance via attenuated innate and adaptive responses by Smith, Tyler A., Ghergherehchi, Cameron L., Mikesh, Michelle, Shores, Jaimie T., Tucker, Haley O., Bittner, George D.

“…Ablation/segmental loss peripheral nerve injuries (PNIs) exhibit poor functional recovery due to slow and inaccurate outgrowth of regenerating axons. Viable…”
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Cooperation between SMYD3 and PC4 drives a distinct transcriptional program in cancer cells by Kim, Jin-Man, Kim, Kyunghwan, Schmidt, Thomas, Punj, Vasu, Tucker, Haley, Rice, Judd C, Ulmer, Tobias S, An, Woojin

“…SET and MYND domain containing protein 3 (SMYD3) is a histone methyltransferase, which has been implicated in cell growth and cancer pathogenesis. Increasing…”
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Discovering human diabetes-risk gene function with genetics and physiological assays by Peiris, Heshan, Park, Sangbin, Louis, Shreya, Gu, Xueying, Lam, Jonathan Y., Asplund, Olof, Ippolito, Gregory C., Bottino, Rita, Groop, Leif, Tucker, Haley, Kim, Seung K.

“…Developing systems to identify the cell type-specific functions regulated by genes linked to type 2 diabetes (T2D) risk could transform our understanding of…”
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Coding transcriptome analyses reveal altered functions underlying immunotolerance of PEG-fused rat sciatic nerve allografts by Smith, Tyler A, Ghergherehchi, Cameron L, Tucker, Haley O, Bittner, George D

“…Current methods to repair ablation-type peripheral nerve injuries (PNIs) using peripheral nerve allografts (PNAs) often result in poor functional recovery due…”
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