Search Results - "Tucey, Tim"
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C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins
Published in Mechanisms of ageing and development (01-03-2016)“…•FUdR extends lifespan of C. elegans adapted to hypertonic stress conditions.•FUdR increases resistance to acute hypertonic stress, thermal stress, and…”
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C. elegans Notch Signaling Regulates Adult Chemosensory Response and Larval Molting Quiescence
Published in Current biology (24-05-2011)“…The conserved DOS-motif proteins OSM-7 and OSM-11 function as coligands with canonical DSL (Delta, Serrate, and LAG-2) ligands to activate C. elegans Notch…”
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OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development
Published in PLoS biology (01-08-2008)“…Notch signaling is critical for cell fate decisions during development. Caenorhabditis elegans and vertebrate Notch ligands are more diverse than classical…”
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lin-12 Notch functions in the adult nervous system of C. elegans
Published in BMC neuroscience (12-07-2005)“…Notch signaling pathways are conserved across species and traditionally have been implicated in cell fate determination during embryonic development. Notch…”
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