Search Results - "Tuberty, Lynda"
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The RAS-Binding Domain of Human BRAF Protein Serine/Threonine Kinase Exhibits Allosteric Conformational Changes upon Binding HRAS
Published in Structure (London) (04-08-2015)“…RAS binding is a critical step in the activation of BRAF protein serine/threonine kinase and stimulation of the mitogen-activated protein kinase signaling…”
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Journal Article -
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Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation
Published in Science advances (08-07-2022)“…Key proteins of retroviruses and other RNA viruses are translated and subsequently processed from polyprotein precursors by the viral protease (PR). Processing…”
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Journal Article -
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Structure-function analysis of the non-helicase domain of SGS1, the Bloom Syndrome ortholog from Saccharomyces cerevisiae
Published 01-01-2011“…Bloom’s Syndrome (BS) is a rare human disease characterized by genome instability and cancer predispostion. The gene mutated in BS, BLM, encodes a member of…”
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Dissertation