Search Results - "Tuano, Natasha"
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1
HDAC inhibition attenuates cardiac hypertrophy by acetylation and deacetylation of target genes
Published in Epigenetics (04-05-2015)“…Pharmacological histone deacetylase (HDAC) inhibitors attenuate pathological cardiac remodeling and hypertrophic gene expression; yet, the direct histone…”
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2
Set7 mediated interactions regulate transcriptional networks in embryonic stem cells
Published in Nucleic acids research (02-11-2016)“…Histone methylation by lysine methyltransferase enzymes regulate the expression of genes implicated in lineage specificity and cellular differentiation. While…”
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3
CRISPR screens identify gene targets at breast cancer risk loci
Published in Genome Biology (29-03-2023)“…Genome-wide association studies (GWAS) have identified > 200 loci associated with breast cancer risk. The majority of candidate causal variants are in…”
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CRISPRi enables isoform-specific loss-of-function screens and identification of gastric cancer-specific isoform dependencies
Published in Genome Biology (26-01-2021)“…Genes contain multiple promoters that can drive the expression of various transcript isoforms. Although transcript isoforms from the same gene could have…”
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5
Chromatin interactome mapping at 139 independent breast cancer risk signals
Published in Genome Biology (07-01-2020)“…Genome-wide association studies have identified 196 high confidence independent signals associated with breast cancer susceptibility. Variants within these…”
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Author Correction: CRISPRi enables isoform-specific loss-of-function screens and identification of gastric cancer-specific isoform dependencies
Published in Genome Biology (25-03-2021)“…An amendment to this paper has been published and can be accessed via the original article…”
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Current perspectives in Set7 mediated stem cell differentiation
Published in Non-coding RNA (04-12-2016)“…Set7 is a key regulatory enzyme involved in the methylation of lysine residues of histone and non-histone proteins. This lysine methyltransferase is induced…”
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Set7 regulates smooth muscle cell differentiation
Published in Atherosclerosis (01-08-2017)Get full text
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