Search Results - "Tuğba ERYİĞİT"
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The Role of Rho/Rho-Kinase Pathway in the Pathophysiology of Absence Epilepsy
Published in Archives of Epilepsy (01-04-2019)“…Objectives:Rho/Rho-kinase (ROCK) signaling has been shown to contribute to neuroinflammation, epileptogenesis, and seizures in convulsivetype epilepsy models…”
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Suppressive effect of Rho-kinase inhibitors Y-27632 and fasudil on spike-and-wave discharges in genetic absence epilepsy rats from Strasbourg (GAERS)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-11-2018)“…Rho/Rho-kinase (ROCK) signaling contributes to neuroinflammation, epileptogenesis, and seizures in convulsive-type epilepsies. However, this pathway has not…”
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IL-1β is induced in reactive astrocytes in the somatosensory cortex of rats with genetic absence epilepsy at the onset of spike-and-wave discharges, and contributes to their occurrence
Published in Neurobiology of disease (01-12-2011)“…Abstract Interleukin (IL)-1β plays a crucial role in the mechanisms of limbic seizures in rodent models of temporal lobe epilepsy. We addressed whether…”
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The α2C-adrenoceptor antagonist JP-1302 controls behavioral parameters, tyrosine hydroxylase activity and receptor expression in a rat model of ketamine-induced schizophrenia-like deficits
Published in Pharmacology, biochemistry and behavior (01-11-2022)“…Schizophrenia is a chronic disabling disease affecting 1 % of the population. Current antipsychotics have limited efficacy in mitigating the severity of the…”
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The α 2C -adrenoceptor antagonist JP-1302 controls behavioral parameters, tyrosine hydroxylase activity and receptor expression in a rat model of ketamine-induced schizophrenia-like deficits
Published in Pharmacology, biochemistry and behavior (01-11-2022)“…Schizophrenia is a chronic disabling disease affecting 1 % of the population. Current antipsychotics have limited efficacy in mitigating the severity of the…”
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Prolongation of absence seizures and changes in serotonergic and dopaminergic neurotransmission by nigrostriatal pathway degeneration in genetic absence epilepsy rats
Published in Pharmacology, biochemistry and behavior (01-02-2022)“…Basal ganglia structures play an important role in the pathophysiology of absence epilepsy, known as remote control of absence seizures. We examined the role…”
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The role of the substantia nigra pars reticulata in kindling resistance in rats with genetic absence epilepsy
Published in Epilepsia (Copenhagen) (01-11-2015)“…Summary Objective Genetic Absence Epilepsy Rats from Strasbourg (GAERS) show a resistance to secondary generalization of focal limbic seizures evoked by…”
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IL-1[beta] is induced in reactive astrocytes in the somatosensory cortex of rats with genetic absence epilepsy at the onset of spike-and-wave discharges, and contributes to their occurrence
Published in Neurobiology of disease (01-12-2011)“…Interleukin (IL)-1[beta] plays a crucial role in the mechanisms of limbic seizures in rodent models of temporal lobe epilepsy. We addressed whether activation…”
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Journal Article