Search Results - "Tu, Tsang‐Wei"
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Radiological-pathological correlation of diffusion tensor and magnetization transfer imaging in a closed head traumatic brain injury model
Published in Annals of neurology (01-06-2016)“…Objective Metrics of diffusion tensor imaging (DTI) and magnetization transfer imaging (MTI) can detect diffuse axonal injury in traumatic brain injury (TBI)…”
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Quantification of increased cellularity during inflammatory demyelination
Published in Brain (London, England : 1878) (01-12-2011)“…Multiple sclerosis is characterized by inflammatory demyelination and irreversible axonal injury leading to permanent neurological disabilities. Diffusion…”
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MR‐guided pulsed focused ultrasound improves mesenchymal stromal cell homing to the myocardium
Published in Journal of cellular and molecular medicine (01-11-2020)“…Image‐guided pulsed focused ultrasound (pFUS) is a non‐invasive technique that can increase tropism of intravenously (IV)‐infused mesenchymal stromal cells…”
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In vivo imaging of sterile microglial activation in rat brain after disrupting the blood-brain barrier with pulsed focused ultrasound: [18F]DPA-714 PET study
Published in Journal of neuroinflammation (25-07-2019)“…Magnetic resonance imaging (MRI)-guided pulsed focused ultrasound combined with the infusion of microbubbles (pFUS+MB) induces transient blood-brain barrier…”
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Focused ultrasound activates voltage-gated calcium channels through depolarizing TRPC1 sodium currents in kidney and skeletal muscle
Published in Theranostics (01-01-2019)“…Pulsed focused ultrasound (pFUS) technology is being developed for clinical neuro/immune modulation and regenerative medicine. Biological signal transduction…”
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MRI and histological evaluation of pulsed focused ultrasound and microbubbles treatment effects in the brain
Published in Theranostics (01-01-2018)“…Magnetic resonance imaging (MRI)-guided pulsed focused ultrasound (pFUS) combined with microbubbles (MB) contrast agent infusion has been shown to transiently…”
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On the detection of cerebral metabolic depression in experimental traumatic brain injury using Chemical Exchange Saturation Transfer (CEST)-weighted MRI
Published in Scientific reports (12-01-2018)“…Metabolic abnormalities are commonly observed in traumatic brain injury (TBI) patients exhibiting long-term neurological deficits. This study investigated the…”
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Simultaneous and noninvasive imaging of cerebral oxygen metabolic rate, blood flow and oxygen extraction fraction in stroke mice
Published in NeuroImage (Orlando, Fla.) (01-01-2013)“…Many brain diseases have been linked to abnormal oxygen metabolism and blood perfusion; nevertheless, there is still a lack of robust diagnostic tools for…”
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Comparison of in vivo and in situ detection of hippocampal metabolites in mouse brain using 1H‐MRS
Published in NMR in biomedicine (01-02-2021)“…The study of cerebral metabolites relies heavily on detection methods and sample preparation. Animal experiments in vivo require anesthetic agents that can…”
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Molecular and histological effects of MR-guided pulsed focused ultrasound to the rat heart
Published in Journal of translational medicine (13-12-2017)“…Image-guided high intensity focused ultrasound has been used as an extracorporeal cardiac pacing tool and to enhance homing of stem cells to targeted tissues…”
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A Baboon Brain Atlas for Magnetic Resonance Imaging and Positron Emission Tomography Image Analysis
Published in Frontiers in neuroanatomy (14-01-2022)“…The olive baboon ( ) is phylogenetically proximal to humans. Investigation into the baboon brain has shed light on the function and organization of the human…”
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Diffusion Tensor Imaging and Chemical Exchange Saturation Transfer MRI Evaluation on the Long-Term Effects of Pulsed Focused Ultrasound and Microbubbles Blood Brain Barrier Opening in the Rat
Published in Frontiers in neuroscience (25-08-2020)“…Blood-brain barrier opening (BBBO) with pulsed Focused Ultrasound (pFUS) and microbubbles (MB) has received increasing interest as a method for…”
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Diffusion tensor imaging detects treatment effects of FTY720 in experimental autoimmune encephalomyelitis mice
Published in NMR in biomedicine (01-12-2013)“…Fingolimod (FTY720) is an orally available sphingosine‐1‐phosphate (S1P) receptor modulator reducing relapse frequency in patients with relapsing–remitting…”
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The impact of myelination on axon sparing and locomotor function recovery in spinal cord injury assessed using diffusion tensor imaging
Published in NMR in biomedicine (01-11-2013)“…The dysmyelinated axons of shiverer mice exhibit impaired conduction characteristics, similar to early postnatal axons before myelination, whereas the patterns…”
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Dose Effect of Mesenchymal Stromal Cell Delivery Through Cardiopulmonary Bypass
Published in The Annals of thoracic surgery (01-12-2023)“…Neurologic impairments are a significant concern for survivors after pediatric cardiac surgery with cardiopulmonary bypass (CPB). We have previously shown that…”
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Comparison of in vivo and in situ detection of hippocampal metabolites in mouse brain using 1 H-MRS
Published in NMR in biomedicine (01-02-2021)“…The study of cerebral metabolites relies heavily on detection methods and sample preparation. Animal experiments in vivo require anesthetic agents that can…”
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Abnormal Injury Response in Spontaneous Mild Ventriculomegaly Wistar Rat Brains: A Pathological Correlation Study of Diffusion Tensor and Magnetization Transfer Imaging in Mild Traumatic Brain Injury
Published in Journal of neurotrauma (01-01-2017)“…Spontaneous mild ventriculomegaly (MVM) was previously reported in ∼43% of Wistar rats in association with vascular anomalies without phenotypic manifestation…”
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Imaging of Spontaneous Ventriculomegaly and Vascular Malformations in Wistar Rats: Implications for Preclinical Research
Published in Journal of neuropathology and experimental neurology (01-12-2014)“…ABSTRACTWistar rats are widely used in biomedical research and commonly serve as a model organism in neuroscience studies. In most cases when noninvasive…”
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Mesenchymal Stromal Cell Delivery Via Cardiopulmonary Bypass Provides Neuroprotection in a Juvenile Porcine Model
Published in JACC. Basic to translational science (01-12-2023)“…Oxidative/inflammatory stresses due to cardiopulmonary bypass (CPB) cause prolonged microglia activation and cortical dysmaturation, thereby contributing to…”
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