Search Results - "Tu, Shih‐Hsin"

An apple a day to prevent cancer formation: Reducing cancer risk with flavonoids by Tu, Shih-Hsin, Chen, Li-Ching, Ho, Yuan-Soon

“…The purpose of this review is to update and discuss key findings from in vitro and in vivo studies on apple and its biocompounds, with a special focus on its…”
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Membrane protein-regulated networks across human cancers by Lin, Chun-Yu, Lee, Chia-Hwa, Chuang, Yi-Hsuan, Lee, Jung-Yu, Chiu, Yi-Yuan, Wu Lee, Yan-Hwa, Jong, Yuh-Jyh, Hwang, Jenn-Kang, Huang, Sing-Han, Chen, Li-Ching, Wu, Chih-Hsiung, Tu, Shih-Hsin, Ho, Yuan-Soon, Yang, Jinn-Moon

“…Alterations in membrane proteins (MPs) and their regulated pathways have been established as cancer hallmarks and extensively targeted in clinical…”
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Apple Polyphenol Phloretin Inhibits Colorectal Cancer Cell Growth via Inhibition of the Type 2 Glucose Transporter and Activation of p53-Mediated Signaling by Lin, Sheng-Tsai, Tu, Shih-Hsin, Yang, Po-Sheng, Hsu, Sung-Po, Lee, Wei- Hwa, Ho, Chi-Tang, Wu, Chih-Hsiung, Lai, Yu-Hsin, Chen, Ming-Yao, Chen, Li-Ching

“…Glucose transporters (GLUTs) are required for glucose uptake in malignant cells, and they can be used as molecular targets for cancer therapy. An RT-PCR…”
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DNA primase polypeptide 1 (PRIM1) involves in estrogen‐induced breast cancer formation through activation of the G2/M cell cycle checkpoint by Lee, Wei‐Hwa, Chen, Li‐Ching, Lee, Chia‐Jung, Huang, Chi‐Cheng, Ho, Yuan‐Soon, Yang, Po‐Sheng, Ho, Chi‐Tang, Chang, Hang‐Lung, Lin, I‐Hsuan, Chang, Hui‐Wen, Liu, Yun‐Ru, Wu, Chih‐Hsiung, Tu, Shih‐Hsin

“…The DNA primase polypeptide 1 (PRIM1) is responsible for synthesizing small RNA primers for Okazaki fragments generated during discontinuous DNA replication…”
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Multi-gene signature of microcalcification and risk prediction among Taiwanese breast cancer by Tsai, Hsin-Tien, Huang, Ching-Shui, Tu, Chao-Chiang, Liu, Chih-Yi, Huang, Chi-Jung, Ho, Yuan-Soon, Tu, Shih-Hsin, Tseng, Ling-Ming, Huang, Chi-Cheng

“…Microcalcification is one of the most common radiological and pathological features of breast ductal carcinoma in situ (DCIS), and to a lesser extent, invasive…”
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Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1 by Jin, Guoxiang, Lee, Szu-Wei, Zhang, Xian, Cai, Zhen, Gao, Yuan, Chou, Ping-Chieh, Rezaeian, Abdol Hossein, Han, Fei, Wang, Chi-Yun, Yao, Juo-Chin, Gong, Zhaohui, Chan, Chia-Hsin, Huang, Chih-Yang, Tsai, Fuu-Jen, Tsai, Chang-Hai, Tu, Shih-Hsin, Wu, Chih-Hsiung, Sarbassov, Dos D., Ho, Yuan-Soon, Lin, Hui-Kuan

“…The regulation of RagAGTP is important for amino-acid-induced mTORC1 activation. Although GATOR1 complex has been identified as a negative regulator for mTORC1…”
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Overexpression and Activation of the α9-Nicotinic Receptor During Tumorigenesis in Human Breast Epithelial Cells by Lee, Chia-Hwa, Huang, Ching-Shui, Chen, Ching-Shyang, Tu, Shih-Hsin, Wang, Ying-Jan, Chang, Yu-Jia, Tam, Ka-Wai, Wei, Po-Li, Cheng, Tzu-Chun, Chu, Jan-Show, Chen, Li-Ching, Wu, Chih-Hsiung, Ho, Yuan-Soon

“…Background Large epidemiological cohort studies in the United States have indicated that active and passive smoking are associated with increased breast cancer…”
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Concurrent gene signatures for han chinese breast cancers by Huang, Chi-Cheng, Tu, Shih-Hsin, Lien, Heng-Hui, Jeng, Jaan-Yeh, Huang, Ching-Shui, Huang, Chi-Jung, Lai, Liang-Chuan, Chuang, Eric Y

“…The interplay between copy number variation (CNV) and differential gene expression may be able to shed light on molecular process underlying breast cancer and…”
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The α9 Nicotinic Acetylcholine Receptor Mediates Nicotine-Induced PD-L1 Expression and Regulates Melanoma Cell Proliferation and Migration by Nguyen, Hai Duong, Liao, You-Cheng, Ho, Yuan-Soon, Chen, Li-Ching, Chang, Hui-Wen, Cheng, Tzu-Chun, Liu, Donald, Lee, Woan-Ruoh, Shen, Shing-Chuan, Wu, Chih-Hsiung, Tu, Shih-Hsin

“…Cigarette smoking is associated with an increased risk of melanoma metastasis. Smokers show higher PD-L1 expression and better responses to PD-1/PD-L1…”
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Tumor targeting and therapeutic assessments of RNA nanoparticles carrying α9-nAChR aptamer and anti-miR-21 in triple-negative breast cancers by Liao, You-Cheng, Cheng, Tzu-Chun, Tu, Shih-Hsin, Chang, Jungshan, Guo, Peixuan, Chen, Li-Ching, Ho, Yuan-Soon

“…Triple-negative breast cancer (TNBC) is highly aggressive with a poor prognosis because of a lack of cell markers as drug targets. α9-Nicotinic acetylcholine…”
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The impact of the effectiveness of GATA3 as a prognostic factor in breast cancer by Fararjeh, Abdul-Fattah Salah, Tu, Shih-Hsin, Chen, Li-Ching, Liu, Yun-Ru, Lin, Yen-Kuang, Chang, Hang-Lung, Chang, Hui-Wen, Wu, Chih-Hsiung, Hwang-Verslues, Wendy W., Ho, Yuan-Soon

“…The transcription factor GATA3 plays a significant role in mammary gland development and differentiation. We analyzed expression of GATA3 in breast cancer (BC)…”
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Long‐term exposure to extremely low‐dose of nicotine and 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK) induce non‐malignant breast epithelial cell transformation through activation of the a9‐nicotinic acetylcholine receptor‐mediated signaling pathway by Fararjeh, Abdul‐Fattah Salah, Tu, Shih‐Hsin, Chen, Li‐Ching, Cheng, Tzu‐Chun, Liu, Yun‐Ru, Chang, Hang‐Lung, Chang, Hui‐Wen, Huang, Chi‐Cheng, Wang, Hwa‐Chain Robert, Hwang‐Verslues, Wendy W., Wu, Chih‐Hsiung, Ho, Yuan‐Soon

“…Breast cancer (BC) is the most common cancer affecting women worldwide and has been associated with active tobacco smoking. Low levels of nicotine (Nic) and…”
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Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients by Tu, Shih-Hsin, Huang, Wan-Ting, Chew, Chee Ho, Chen, Amanda Lin, Chen, Shou-Tung, Chen, Jin-Hua, Hsieh, Yi-Chen, Chen, Chien-Chung

“…Breast cancer is a severe public health problem, and early treatment with powerful anticancer drugs is critical for success. The researchers investigated the…”
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Proteasome 26S Subunit, non-ATPase 3 (PSMD3) Regulates Breast Cancer by Stabilizing HER2 from Degradation by Fararjeh, Abdulfattah Salah, Chen, Li-Ching, Ho, Yuan-Soon, Cheng, Tzu-Chun, Liu, Yun-Ru, Chang, Hang-Lung, Chang, Hui-Wen, Wu, Chih-Hsiung, Tu, Shih-Hsin

“…It is well-known that human epidermal growth factor receptor 2 (HER2) is critical for breast cancer (BC) development and progression. Several studies have…”
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Oestrogen receptor-regulated glutathione S-transferase mu 3 expression attenuates hydrogen peroxide-induced cytotoxicity, which confers tamoxifen resistance on breast cancer cells by Lin, Juo-Han, Tu, Shih-Hsin, Chen, Li-Ching, Huang, Chi-Cheng, Chang, Hang-Lung, Cheng, Tzu-Chun, Chang, Hui-Wen, Wu, Chih-Hsiung, Wu, Han-Chung, Ho, Yuan-Soon

“…Purpose Glutathione S-transferase mu 3 (GSTM3) is an enzyme involving in the detoxification of electrophilic compounds by conjugation with glutathione. Higher…”
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Type-3 Hyaluronan Synthase Attenuates Tumor Cells Invasion in Human Mammary Parenchymal Tissues by Lee, Wen-Jui, Tu, Shih-Hsin, Cheng, Tzu-Chun, Lin, Juo-Han, Sheu, Ming-Thau, Kuo, Ching-Chuan, Changou, Chun A, Wu, Chih-Hsiung, Chang, Hui-Wen, Chang, Hang-Lung, Chen, Li-Ching, Ho, Yuan-Soon

“…The microenvironment for tumor growth and developing metastasis should be essential. This study demonstrated that the hyaluronic acid synthase 3 (HAS3) protein…”
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Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins by Chen, Ching-Shyang, Lee, Chia-Hwa, Hsieh, Chang-Da, Ho, Chi-Tang, Pan, Min-Hsiung, Huang, Ching-Shui, Tu, Shih-Hsin, Wang, Ying-Jan, Chen, Li-Ching, Chang, Yu-Jia, Wei, Po-Li, Yang, Yi-Yuan, Wu, Chih-Hsiung, Ho, Yuan-Soon

“…Previous studies have demonstrated that the persistent exposure of human bronchial epithelial cells to nicotine (Nic) through nicotinic acetylcholine receptors…”
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The learning curve of endoscopic total mastectomy in Taiwan: A multi-center study by Hung, Chin-Sheng, Chang, Sheng-Wei, Liao, Li-Min, Huang, Cheng-Chiao, Tu, Shih-Hsin, Chen, Shou-Tung, Chen, Dar-Ren, Kuo, Shou-Jen, Lai, Hung-Wen, Chou, Ting-Mao, Kuo, Yao-Lung

“…Laparoscopic techniques are commonly used in abdominal and gynecologic surgery, while breast cancer surgery has remained largely unchanged. In Asia, especially…”
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Melatonin promotes neuroblastoma cell differentiation by activating hyaluronan synthase 3‐induced mitophagy by Lee, Wen‐Jui, Chen, Li‐Ching, Lin, Juo‐Han, Cheng, Tzu‐Chun, Kuo, Ching‐Chuan, Wu, Chih‐Hsiung, Chang, Hui‐Wen, Tu, Shih‐Hsin, Ho, Yuan‐Soon

“…Neuroblastoma is the second most common pediatric malignancy and has a high rate of spontaneous remission. Uncovering the mechanisms underlying neuroblastoma…”
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The extended concurrent genes signature for disease-free survival in breast cancer by Huang, Ching-Shui, Tsai, Ming-Lin, Lu, Tzu-Pin, Tu, Chao-Chiang, Liu, Chih-Yi, Huang, Chi-Jung, Ho, Yuan-Soon, Tu, Shih-Hsin, Chuang, Eric Y., Tseng, Ling-Ming, Huang, Chi-Cheng

“…Previously we had identified concurrent genes, which highlighted the interplay between copy number variation (CNV) and differential gene expression (GE) for…”
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